Results 31 to 40 of about 73,008,320 (286)

IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. [PDF]

, 2013
Type 2 immune responses are essential in protection against intestinal helminth infections. In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti ...
Stockinger, Brigitta, Helmby, Helena, Brigitta Stockinger, Helmby Helena, Turner, Jan-Eric, Helena Helmby, Turner Jan-Eric, Stockinger Brigitta, Jan-Eric Turner   +8 more
core   +1 more source

Association of interleukin 22 gene polymorphisms and serum IL-22 level with risk of systemic lupus erythematosus in a Chinese population [PDF]

Clinical and Experimental Immunology, 2018
Summary The aim of this study was to investigate the association between the single-nucleotide polymorphisms (SNPs) of the interleukin 22 (IL-22) gene and systemic lupus erythematosus (SLE) in a Chinese population. Three IL-22 SNPs (rs2227485, rs2227513 and rs2227491) were genotyped using SNaPshot SNP genotyping assays and identified by ...
R Wang, Y-L Zeng, H-M Qin, Y-L Lu, H-T Huang, M Lei, T Tan, Y-Y Huang, H-C Luo, Y Lan, Y-S Wei   +10 more
openaire   +2 more sources

Interleukin-22 and connective tissue diseases: emerging role in pathogenesis and therapy

Cell & Bioscience, 2021
Interleukin-22 (IL-22), a member of the IL-10 family of cytokines, is produced by a number of immune cells involved in the immune microenvironment of the body.
Xiuyun Xuan, Lin Zhang, Chunxia Tian, Ting Wu, Haihua Ye, Juanmei Cao, Fangqi Chen, Yan Liang, Huilan Yang, Changzheng Huang   +9 more
doaj   +1 more source

Serum interleukin-22 (IL-22) is increased in the early stage of Hashimoto’s thyroiditis compared to non-autoimmune thyroid disease and healthy controls [PDF]

Hormones, 2014
Hashimoto's thyroiditis (HT) is considered to be a Th1-related autoimmune disease (AID). Recent studies revealed that Th17 lymphocytes (producing mostly IL-17, IL-21 and IL-22) play a major role in numerous AIDs commonly thought to be Th1 diseases.
RUGGERI, Rosaria Maddalena, MINCIULLO, PAOLA LUCIA, SAITTA, SALVATORE, GIOVINAZZO, SALVATORE, Rosaria Certo, CAMPENNI', Alfredo, TRIMARCHI, Francesco, GANGEMI, Sebastiano, BENVENGA, Salvatore   +8 more
openaire   +3 more sources

The Interleukin-10 Family of Cytokines and Their Role in the CNS

Frontiers in Cellular Neuroscience, 2018
Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R. Burmeister, Ian Marriott
doaj   +1 more source

Examining the role of salivary IL-2 and IL-22 in recurrent aphthous stomatitis: a diagnostic approach

Journal of Ideas in Health
Background: Recurrent aphthous stomatitis (RAS) is a prevalent inflammatory condition, that manifests as mouth ulcers. This study aims to evaluate IL-2 and IL-22 levels in saliva samples of individuals with recurrent aphthous stomatitis (RAS) compared ...
Mustafa Taher
doaj   +3 more sources

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]

, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core   +2 more sources

The Role of Interleukin-22 in The Diagnosis and Evaluation of Disease Activity in Rheumatoid Arthritis

مجلة الكوفة الطبية, 2023
Background: Rheumatoid Arthritis (RA) is a chronic autoimmune disease that primarily affects small joints, resulting in joint inflammation, pain, and limited mobility.
Shihab Almurshedi, Raad Alasady
doaj   +1 more source

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma

Advanced Biomedical Research, 2014
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani, Roya Sherkat, Mazdak Ganjalikhani Hakemi, Nahid Eskandari, Reza Yazdani   +4 more
doaj   +1 more source

Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis

Frontiers in Immunology
IntroductionInfluenza-associated pulmonary aspergillosis (IAPA) is a severe complication of influenza infection that occurs in critically ill patients and results in higher mortality compared to influenza infection alone.
Aijaz Ahmad, Ravineel B. Singh, Kara L. Nickolich, Matthew J. Pilewski, Caden Ngeow, Kwame Frempong-Manso, Keven M. Robinson   +6 more
doaj   +1 more source