Interleukin 25 and its biological features and function in intestinal diseases [PDF]
Central European Journal of Immunology, 2023 Interleukin 25 (IL-25), also known as IL-17E, is a member of the IL-17 cytokine family and an important regulator of the type 2 immune response. Accumulating evidence suggests that IL-25 interacts with diverse immune as well as non-immune cells and plays
Wei Jiang +3 more
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The potential roles of interleukin-25 in infectious diseases [PDF]
Frontiers in Immunology, 2022 Interleukin-25 (IL-25), also known as IL-17E, is a recently identified cytokine of the IL-17 family. Numerous studies illustrated that the expression of IL-25 is regulated by multiple pathogens, including parasitic, viral, and bacterial infections. IL-25
Jing Wu +8 more
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New insights into the function of Interleukin-25 in disease pathogenesis [PDF]
Biomarker Research, 2023 Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells.
Qingfang Yuan +7 more
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Interleukin‐25: New perspective and state‐of‐the‐art in cancer prognosis and treatment approaches [PDF]
Cancer Medicine, 2021 Cancer is a leading cause of death which imposes a substantial financial burden. Among the several mechanisms involved in cancer progression, imbalance of immune cell‐derived factors such as cytokines and chemokines plays a central role.
Arezoo Gowhari Shabgah +7 more
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Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions [PDF]
Frontiers in Immunology, 2022 Diabetic foot ulcer (DFU) frequently leads to non-traumatic amputation and finally even death. However, the mechanism of DFU is not fully understood.
Fang Zhang +10 more
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The expression of interleukin-25 increases in human coronary artery disease and is associated with the severity of coronary stenosis [PDF]
Anatolian Journal of Cardiology, 2020 Objective: Interleukin (IL) 25, also known as IL-17E, is an inflammatory cytokine and has been demonstrated to be closely related to cardiovascular diseases by regulating immunity and inflammation, including atherosclerosis.
Yao Xu +8 more
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Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma [PDF]
Clinical and Translational Allergy, 2018 Background Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways.
Wei Tang +10 more
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Interleukin-25 Produced by Synoviocytes Has Anti-inflammatory Effects by Acting As a Receptor Antagonist for Interleukin-17A Function [PDF]
Frontiers in Immunology, 2017 The production and function of cytokines are highly regulated. One mechanism is the balance between pro- and anti-inflammatory cytokines. As interleukin (IL)-17A and IL-25 share the IL-17RA receptor chain, we hypothesize that IL-25 acts as an IL-17A ...
Fabien Lavocat +2 more
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Potential Role of Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin-Fibrocyte Axis in the Pathogenesis of Allergic Airway Diseases [PDF]
Chinese Medical Journal, 2018 Objective: Allergic airway diseases (AADs) are a group of heterogeneous disease mediated by T-helper type 2 (Th2) immune response and characterized with airway inflammation and remodeling, including allergic asthma, allergic rhinitis, and chronic ...
Xiu-Juan Yao +2 more
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Interleukin-25 enhances humoral immune responses caused by the rabies virus [PDF]
Virulence, 2022 Rabies is an important zoonotic disease caused by the rabies virus (RABV). Currently, no effective treatment is available for this condition. The prevention and control of rabies mainly depend on effective vaccination. Therefore, it is crucial to enhance
Yue Zhang +7 more
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