Results 41 to 50 of about 4,841,277 (301)

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma

Advanced Biomedical Research, 2014
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani, Roya Sherkat, Mazdak Ganjalikhani Hakemi, Nahid Eskandari, Reza Yazdani   +4 more
doaj   +1 more source

Cellular networks controlling Th2 polarization in allergy and immunity [PDF]

, 2012
In contrast to the development of Th1 (type 1 T helper cells), Th17 and Treg (regulatory T cells), little is known of the mechanisms governing Th2 development, which is important for immunity to helminths and for us to understand the pathogenesis of ...
Kool, Mirjam, Hammad, Hamida, Lambrecht, Bart   +2 more
core   +1 more source

Regnase-1 degradation is crucial for interleukin-33- and interleukin-25-mediated ILC2 activation.

JCI Insight, 2020
Group-2 innate lymphoid cells (ILC2s) are a critical innate source of type-2 cytokines in allergic inflammation. Although ILC2s are recognized as a critical cell population in the allergic inflammation, the regulatory mechanism(s) of ILC2s are less well ...
Kazufumi Matsushita, Hiroki Tanaka, K. Yasuda, Takumi Adachi, A. Fukuoka, Shoko Akasaki, Atsuhide Koida, E. Kuroda, S. Akira, T. Yoshimoto   +9 more
semanticscholar   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A, Lund, Sean, Walford, Hannah H   +2 more
core   +2 more sources

Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection. [PDF]

, 2018
Innate immune cells quickly infiltrate the site of pathogen entry and not only stave off infection but also initiate antigen presentation and promote adaptive immunity.
A Gladiator, A Ray, AC Patera, AD Joshi, AK Furuya, AM Owyang, AV Ivanov, AY Wen, BC Xu, C Zhao, CE Andoniou, CO Simon, CR Crowe, CW Lio, D Burdette, EH Kobayashi, GJ Bancroft, GM DeNicola, H Kato, H Kawasaki, HS Zhang, HY Cho, J Bystrom, J Lee, JL Bowen, JM Lee, K Tabeta, KA Daniels, KJ Livak, KL Hokeness, KL Hokeness, KM Hsu, LR Johnson, M Boeckh, M Wagner, MA Stacey, MC Cheeran, MJ Crane, MJ Kesic, MJ Reddehase, MK Arababadi, N Nagai, NM Reddy, P Balanescu, P Ye, Q Ma, R Guabiraba, R Saddawi-Konefka, R Seelige, R Seelige, RK Thimmulappa, RL Wheat, S Jonjic, S Jordan, S Kohyama, S Mamo, S Schaedler, S Sell, SL Deshmane, SL Gaffen, SP Francis, T O’Sullivan, T Starnes, TP Salazar-Mather, V Ramirez-Carrozzi, VA Rathinam, W Hou, W Hou, X Song, X Wang, Y Iwakura, Y Shinkai, Y Yageta, Y Zhang, YL Cheng, Z Huang   +75 more
core   +3 more sources

Evaluation of Sensitivity and Specificity of Interleukins 25 and 33 in Diagnosis of Pediatric Asthma

Journal of Pure and Applied Microbiology, 2021
The roles of interleukin 25 (a member of the interleukin 17 family) and interleukin 33 (a member of the interleukin 1 family) in asthma and airway hyperresponsiveness are yet to be fully understood.
Abeer Thaher Naji AL-Hasnawi
doaj   +1 more source

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. [PDF]

, 2014
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays a critical role in the development of the obesity-associated inflammatory diseases, including insulin resistance and atherosclerosis.
DeFranco, Anthony L, Dicorleto, Paul E, Febbraio, Maria, Fox, Paul L, Harding, Clifford V, Hazen, Stanley L, Hise, Amy G, Hu, Bingqing, Li, Xiaoxia, Morton, Richard E, Nagy, Laura E, Ransohoff, Richard M, Roychowdhury, Sanjoy, Schmitt, David, Smith, Jonathan D, Wang, Jian-an, Xiao, Nengming, Yu, Minjia, Zhao, Junjie, Zhou, Hao   +19 more
core   +2 more sources

Beneficial autoimmunity at body surfaces – immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer [PDF]

, 2014
Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental ...
Agrawal, Aguado, Al-Shami, Allakhverdi, Angkasekwinai, Arwert, Balkwill, Bas, Björkström, Blais, Boyden, Briot, Bryson, Burnet, Burnet, Cella, Cerwenka, Champsaur, Chan, Chao, Chavanas, Chen, Chen, Cheroutre, Conticello, Coussens, Culig, Dalton, Dearman, Deleuran, Demehri, DePinho, Devey, Di Piazza, Dighe, Dunham, Dunn, Dvorak, Ehrlich, Eisenbarth, Ellyard, Engkilde, Eyerich, Farhadi, Felices, Fort, Fritz, Fujisawa, Fukuyama, Furmanski, Fux, Gause, Gebhardt, Giangreco, Girardi, Girardi, Girardi, Golumbek, Gregory, Groh, Gutierrez, Hallett, Hammad, Hams, Harris, Hayday, Heneghan, Hock, Hueber, Humphreys, Imai, Indra, Jackson, Jameson, Jameson, Jensen-Jarolim, Jerde, Jiang, Jiang, Josephs, Jotwani, Jovanovic, Jovanovic, Jung, Kaplan, Karagiannis, Kim, Komai-Koma, Kool, Kool, Kouzaki, Kuroda, Lebel-Binay, Lee, Lindelof, Lodoen, Ma, Magalhaes, Magalhaes, Marichal, Marichal, Matsuda, Matzinger, McCoy, McWhorter, Meehan, Metz, Mishra, Moghaddam, Monticelli, Nestle, Nigro, Obiri, Oh, Okumura, Olver, Ortiz-Urda, Owyang, Palm, Palm, Park, Pastorelli, Pearce, Pedroza-Gonzalez, Pericle, Profet, Qi, Ramsbottom, Raulet, Reali, Renard, Rittmeyer, Rodolfo, Rosenberg, Rölle, Saenz, Sagiv, Salgame, Salimi, Schmidt, Schmitz, Schneider, Schonthaler, Senovilla, Shankaran, Sharp, Sherman, Shi, Shibuya, Simson, Skinnider, Smyth, Soriani, South, Strid, Strid, Strid, Suárez-Alvarez, Swamy, Takahashi, Takai, Tan, Tang, Thomas, Traidl-Hoffmann, Turchinovich, Ullrich, Van Belle, Van Hemelrijck, Vantourout, Verdino, Vernersson, Vesely, Villarreal, Walley, Walter, Wang, Wen, Wen, Wilson, Witherden, Witherden, Wood, Yanaba, Yin, Yoo, Zaiss, Zaph, Zaph, Ziegler, Zitvogel   +190 more
core   +2 more sources

The intestinal expulsion of the roundworm Ascaris suum is associated with eosinophils, intra-epithelial T cells and decreased intestinal transit time [PDF]

, 2013
Ascaris lumbricoides remains the most common endoparasite in humans, yet there is still very little information available about the immunological principles of protection, especially those directed against larval stages.
A Fujiwara, A Roepstorff, A Zhao, A Zhao, Aaron R. Jex, BA Vallance, C Dold, C Moolenbeek, C Zhou, CD Criscione, CV Holland, D Leles, D Masure, Dries Masure, DW Crompton, F van Wijk, G Jungersen, GH Liu, HD Dawson, J Vandesompele, JF Urban Jr, Jimmy Saunders, Johnny Vlaminck, Jozef Vercruysse, KD Mccoy, Koen Chiers, L Eriksen, M Ashraf, M Morimoto, N Arizono, N Foster, N Miquel, NL Harris, P Kermanizadeh, P Nejsum, P O'Lorcain, PA Knight, Peter Geldhof, PI Uston, R Shamri, RM Anthony, RW Li, S Rozen, S Schmidt, Sarah Claerhoudt, Tao Wang, TB Stewart, TJ Anderson, Wim Van den Broeck   +48 more
core   +4 more sources

A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]

, 2019
Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole, Ahmed, Norus, Hartmann, Susanne, Heitlinger, Emanuel, Jarquin, Victor Hugo, Jost, Jenny, Kühl, Anja A., Steinfelder, Svenja, Xenophontos, Natasa   +8 more
core   +4 more sources