Results 41 to 50 of about 4,322,877 (234)

Interleukin 25 promotes the initiation of proallergic type 2 responses [PDF]

The Journal of Experimental Medicine, 2007
The molecular mechanisms underlying the initiation of innate and adaptive proallergic type 2 responses are not understood. Interleukin (IL) 25, a member of the IL-17 cytokine family, was recently reported (Owyang, A.M., C. Zaph, E.H. Wilson, K.J. Guild, T. McClanahan, H.R. Miller, D.J. Cua, M. Goldschmidt, C.A. Hunter, R.A. Kastelein, and D.
Angkasekwinai, Pornpimon, Park, Heon, Wang, Yui-Hsi, Wang, Yi-Hong, Chang, Seon Hee, Corry, David B., Liu, Yong-Jun, Zhu, Zhou, Dong, Chen   +8 more
openaire   +2 more sources

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma

Advanced Biomedical Research, 2014
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani, Roya Sherkat, Mazdak Ganjalikhani Hakemi, Nahid Eskandari, Reza Yazdani   +4 more
doaj   +1 more source

Regnase-1 degradation is crucial for interleukin-33- and interleukin-25-mediated ILC2 activation.

JCI Insight, 2020
Group-2 innate lymphoid cells (ILC2s) are a critical innate source of type-2 cytokines in allergic inflammation. Although ILC2s are recognized as a critical cell population in the allergic inflammation, the regulatory mechanism(s) of ILC2s are less well ...
Kazufumi Matsushita, Hiroki Tanaka, K. Yasuda, Takumi Adachi, A. Fukuoka, Shoko Akasaki, Atsuhide Koida, E. Kuroda, S. Akira, T. Yoshimoto   +9 more
semanticscholar   +1 more source

Evaluation of Sensitivity and Specificity of Interleukins 25 and 33 in Diagnosis of Pediatric Asthma

Journal of Pure and Applied Microbiology, 2021
The roles of interleukin 25 (a member of the interleukin 17 family) and interleukin 33 (a member of the interleukin 1 family) in asthma and airway hyperresponsiveness are yet to be fully understood.
Abeer Thaher Naji AL-Hasnawi
doaj   +1 more source

Interleukin-25 and mucosal T cells in noneosinophilic and eosinophilic chronic rhinosinusitis. [PDF]

Annals of Allergy, Asthma & Immunology, 2015
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease of uncertain pathogenesis. Memory T cells acquire additional functions during the secondary response and play important roles in chronic inflammation.To investigate characteristics of tissue memory CD4(+) T cells obtained from patients with noneosinophilic CRSwNP (NECRS) and ...
Tomohisa Iinuma, Y. Okamoto, Heizaburo Yamamoto, Ayako Inamine-Sasaki, Yuji Ohki, Toshioki Sakurai, Urara Funakoshi, S. Yonekura, D. Sakurai, K. Hirahara, T. Nakayama   +10 more
semanticscholar   +3 more sources

Thymic stromal lymphopoietin, OX40‐ligand, and interleukin‐25 in allergic responses [PDF]

Clinical & Experimental Allergy, 2009
Summary Allergic diseases are often triggered by environmental allergens that induce dominant type 2 immune responses, characterized by the infiltrated T‐helper type 2 (TH2) lymphocytes, eosinophils, and elevated TH2 cytokines. In addition to TH2 type immune responses, epithelial stress and injury linked to tissue remodelling are ...
Y-H, Wang, Y-J, Liu
openaire   +2 more sources

IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria

Biochemistry and Biophysics Reports, 2016
IL-25, IL-33 and TSLP, which are produced predominantly by epithelial cells, can induce production of Th2-type cytokines such as IL-4, IL-5 and/or IL-13 by various types of cells, suggesting their involvement in induction of Th2-type cytokine-associated ...
Akiko Shibui, Ayako Takamori, Mohammed E.M. Tolba, Aya Nambu, Eri Shimura, Sachiko Yamaguchi, Chizu Sanjoba, Hajime Suto, Katsuko Sudo, Ko Okumura, Sumio Sugano, Hideaki Morita, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae   +14 more
doaj   +1 more source

A novel immunodeficiency disorder characterized by genetic amplification of interleukin 25 [PDF]

Genes & Immunity, 2011
Many primary immunodeficiency disorders of differing etiologies have been well characterized, and much understanding of immunological processes has been gained by investigating the mechanisms of disease. Here, we have used a whole-genome approach, employing single-nucleotide polymorphism and gene expression microarrays, to provide insight into the ...
Green, Michael, Camilleri, Emily, Gandhi, Maher, Peake, J, Griffiths, Lyn   +4 more
openaire   +3 more sources

Relationship between interleukin 17 & 6 in patients with varicocele compare with a control group [PDF]

Journal of Medical and Life Science, 2019
The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male.
Hayder AL-Msaid, Waleed H., Hydar Khalfa
doaj   +1 more source

Elevated expression of IL-17RB and ST2 on myeloid dendritic cells is associated with a Th2-skewed eosinophilic inflammation in nasal polyps

Clinical and Translational Allergy, 2018
Background Interleukin(IL)-25, IL-33, and thymic stromal lymphopoietin (TSLP) underlie the crosstalk between epithelial cells and dendritic cells (DCs) during the development of Th2 responses.
Rui Zheng, Dan Wang, Kai Wang, Wen-Xiang Gao, Qin-Tai Yang, Li-Jie Jiang, Min Zhou, Yu-Jie Cao, Jianbo Shi, Yueqi Sun   +9 more
doaj   +1 more source