Results 71 to 80 of about 68,824,737 (161)

Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases

Frontiers in Immunology, 2019
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus.
Bernhard F. Gibbs, Nikolaos Patsinakidis, Ulrike Raap   +2 more
doaj   +1 more source

Interleukin-31 Receptor α Is Required for Basal-Like Breast Cancer Progression

Frontiers in Oncology, 2020
Purpose: Interleukin-31 receptor α (IL31RA) usually mediates IL-31 induced inflammation and allergic diseases. However, the functional roles of IL-31/IL31RA signaling in basal-like breast cancer (BLBC) progression remain totally unclear.Methods ...
Yanling He, Xinyuan Zhang, Weijun Pan, Fang Tai, Li Liang, Jian Shi, Jian Shi   +6 more
doaj   +1 more source

IL‐31 transgenic mice show reduced allergen‐induced lung inflammation

, 2020
Interleukin‐31 (IL‐31) is a Th2 cell–derived cytokine that has been closely linked to pruritic skin inflammation. More recently, enhanced IL‐31 serum levels have also been observed in patients with allergic rhinitis and allergic asthma.
Horejs-Hoeck, Jutta, Richard Weiss, Angelika Stoecklinger, Sarajlic, Muamera, Harald Schwarz, Patrick Suchanek, Weiss, Richard, Stacey R. Dillon, Neuper, Theresa, Hammerl, Peter, Stoecklinger, Angelika, Evgeniia Korotchenko, Renate Bauer, Muamera Sarajlic, Korotchenko, Evgeniia, Jutta Horejs‐Hoeck, Strandt, Helen, Suchanek, Patrick, Peter Hammerl, Schwarz, Harald, Dillon, Stacey R., Theresa Neuper, Bauer, Renate, Daniel Neureiter, Neureiter, Daniel, Helen Strandt   +25 more
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IL-31, itch and hematological malignancies

, 2021
Pruritus is one of the most common symptoms experienced by neoplastic patients. The pathogenesis of neoplastic itch is complex and multifactorial and could be due to an unbalanced production of humoral mediators by altered immune effector cells. IL-31 is
Casciaro M., Marco Casciaro, Allegra A., Gangemi S., Sebastiano Gangemi, Alessandro Allegra, Eleonora Di Salvo, Di Salvo E.   +7 more
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Correlation of interleukin 31 serum levels in patients with atopic dermatitis, allergic rhinitis and atopic asthma [PDF]

, 2013
Interleukin 31 (IL-31), merupakan salah satu daripada sitokin yang menjadi pengawal atur yang penting terhadap tindak balas TH2. Kajian terdahulu telah dilakukan oleh Zhang et al.
Mohd @ Muhammad Amin, Siti Noor Syuhada
core   +1 more source

IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells [PDF]

, 2008
Background Production of interferon (IFN)-gamma is key to efficient anti-tumor immunity. The present study was set out to investigate effects of IFNgamma on the release of the potent pro-angiogenic mediator IL-8 by human A549 lung carcinoma cells ...
Bernhard Zwissler, Zwißler, Bernhard, Sadik, Christian David, Pfeilschifter, Josef (Prof. Dr.), Heiko Mühl, Malte Bachmann, Muehl, Heiko, Sadik, Christian D., Josef Pfeilschifter, Christian D Sadik, Pfeilschifter, Josef, Bachmann, Malte, Boost, Kim Alexander, Mühl, Heiko, Kim A Boost, Boost, Kim A.   +15 more
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Interleukin-31 Receptor A Expression in the Dorsal Root Ganglion of Mice with Atopic Dermatitis

, 2023
Atopic dermatitis (AD) is a common skin disease caused by genetic and environmental factors. However, the mechanisms underlying AD development remain unclear.
Arai, Iwao, Iwao Arai, Saito, Saburo, Saburo Saito   +3 more
core   +1 more source

The role of interleukin-31 in human allergic disease [PDF]

, 2013
The newly described cytokine Interleukin (IL) 31 has been shown to be expressed by murine activated T lymphocytes of a Th2 phenotype. Like IL-17 and IL-22, IL-31 is a tissue signalling cytokine whose receptor is mainly found on non-immune cells.
Stott, Bryony Alexandra
core   +1 more source

Interleukin-31 in Respiratory Type 2 Inflammatory Diseases: Mechanistic Insights and Therapeutic Potential [PDF]

Shuang Yao,1,2,* Yan Zhao,1,2,* Zhimeng Li,3,4 Hongfei Lou,5,* Luo Zhang1,2,4,6,* 1Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of ...
Li Z, Yao S, Lou H, Zhang L, Zhao Y
core  

Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]

, 2011
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Jukema, J.W., Trompet, S., Sattar, N., David J. Stott, Jukema, J. Wouter, Heather M. Murray, Ian Ford, Ford, I., Welsh, Paul, Anton J.M. de Craen, McInnes, Iain B., Trompet, Stella, Paul Welsh, J. Wouter Jukema, Westendorp, Rudi G.J., McInnes, I.B., Welsh, P., Westendorp, R.G.J., Packard, C.J., Murray, H.M., Craen, A.J.M. de, de Craen, Anton J.M., Rudi G.J. Westendorp, Sattar, Naveed, Stella Trompet, Stott, David J., Naveed Sattar, Ford, Ian, Chris J. Packard, Murray, Heather M., PROSPER Study Grp, Packard, Chris J., Iain B. McInnes, Stott, D.J.   +33 more
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