Results 51 to 60 of about 68,824,737 (161)

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan, Kronenberger Bernd, Brunner Friederike, Filmann Natalie, Kapper Lisa, Herrmann Eva, Zeuzem Stefan, Mühl Heiko, Rudloff Ina, Piiper Albrecht, Waidmann Oliver, Bachmann Malte, Pfeilschifter Josef   +35 more
core   +2 more sources

IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model

Biology Open, 2019
Interleukin 31 (IL-31) is a four-helix cytokine made predominantly by Th2 CD4+ T cells. It was initially identified as being associated with the promotion of atopic dermatitis, where increased levels of IL-31 levels have been found and IL-31 induced the ...
Junqiong Huang, Huan Yue, Tao Jiang, Jing Gao, Yu Shi, Bin Shi, Xiaoxue Wu, Xiaoqin Gou   +7 more
doaj   +1 more source

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
Domschke, Katharina, Volker Arolt, Walter Heindel, Katharina Domschke, Schoening, Sonja, Bernhard T Baune, Jochen Bauer, Christina Uhlmann, Arolt, V, Heindel, W., Konrad, Carsten, Domschke Katharina, Rauch, AV, Konrad Carsten, Suslow Thomas, Sonja Schöning, Kugel, H., Kugel, Harald, Heindel, W, Heindel, Walter, Konrad, C, Domschke, K, Uhlmann, C., Birosova, E, Udo Dannlowski, Suslow, T., Konrad, C., Baune, Bernhard T., Ohrmann Patricia, Uhlmann, C, Grotegerd Dominik, Patricia Ohrmann, Thomas Suslow, Ohrmann, P, Baune, B., Harald Kugel, Rauch, Astrid V., Astrid V Rauch, Grotegerd, D., Birosova Eva, Dannlowski Udo, Rauch Astrid V, Dannlowski, U, Kugel Harald, Birosova, E., Bauer, Jochen, Grotegerd, D, Grotegerd, Dominik, Arolt Volker, Rauch, A., Suslow, T, Uhlmann Christina, Dannlowski, U., Schöning Sonja, Bauer, J., Eva Birosova, Ohrmann, Patricia, Suslow, Thomas, Birosova, Eva, Kugel, H, Bauer, J, Ohrmann, P., Carsten Konrad, Schoning, S., Baune Bernhard T, Schöning, Sonja, Arolt, Volker, Arolt, V., Uhlmann, Christina, Dannlowski, Udo, Bauer Jochen, Domschke, K., Dominik Grotegerd, Baune, BT, Heindel Walter, Schöning, S, Baune, Bernhard T, Bauer, Jochen ; https://orcid.org/, Rauch, Astrid V   +78 more
core   +2 more sources

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +1 more source

Nemolizumab: un innovador tratamiento biológico para el control de la interleuquina 31 (IL-31) clave en la dermatitis atópica y el prurigo nodular

Actas Dermo-Sifiliográficas, 2022
Resumen: La citoquina IL-31 es una neurocitoquina que estimula las neuronas sensoriales relacionadas con el picor, contribuye a la inflamación, la disfunción y remodelación de la barrera epidérmica. Al interrelacionar los sistemas inmunológico y nervioso
E. Serra-Baldrich, L.F. Santamaría-Babí, J. Francisco Silvestre   +2 more
doaj   +1 more source

Analyzing the Antinociceptive Effect of Interleukin-31 in Mice

, 2023
The theory that an itch inhibits pain has been refuted; however, previous research did not investigate this theory for an interleukin-31 (IL-31)-induced itch.
Minoru Tsuji, Iwao Arai, Saburo Saito, Kohei Takahashi, Hiroshi Takeda   +4 more
core   +1 more source

Rethinking interleukin-31: A neuroimmune orchestrator of itch beyond Th2 immunity

Allergology International
Interleukin (IL)-31 has emerged as a pivotal mediator of pruritus. Since its initial identification, substantial progress has been made in elucidating the role of IL-31 in itch pathophysiology, particularly its direct effects on peripheral sensory ...
Hiroyuki Irie, Kenji Kabashima
doaj   +1 more source

Prenylated quinolinecarboxylic acid compound-18 prevents sensory nerve fiber outgrowth through inhibition of the interleukin-31 pathway.

PLoS ONE, 2021
Interleukin-31 (IL-31) is involved in excessive development of cutaneous sensory nerves in atopic dermatitis (AD), leading to severe pruritus.
Masato Ogura, Kumiko Endo, Toshiyuki Suzuki, Yoshimi Homma   +3 more
doaj   +1 more source

Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]

, 2009
Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.
Dower, S., Zoe Brookes, Nicholas J Alp, Francis, Sheila, Steven Dower, David C Crossman, Brookes, Zoe, Francis, S., Shaw, Gary, Shaw, G., Crossman, D.C., Gary Shaw, Sheila Francis, Graham, Delyth, Brookes, Z., Alp, N.J., Crossman, David C., Chamberlain, J., Delyth Graham, Dower, Steven, Graham, D., Xu, A., Janet Chamberlain, Alp, Nicholas J., Xu, Aimin, Chamberlain, Janet   +25 more
core   +1 more source

Exploring the Potentiality of a Plant Platform for Monoclonal Antibody Production in Veterinary Medicine

Vaccines
Canine atopic dermatitis (CAD) is an allergic, inflammatory, and pruritic skin disease associated with the production of IgE antibodies against environmental allergens and mainly house dust mite allergens.
Bertrand Morel, Claude Favrot, Lucie Mirande, Clemens Grünwald-Gruber, Virginie Stordeur, Louis Philippe Vezina, Loïc Faye, Véronique Gomord   +7 more
doaj   +1 more source