Results 31 to 40 of about 68,824,737 (161)

Interleukin-31 Signaling Bridges the Gap Between Immune Cells, the Nervous System and Epithelial Tissues

Frontiers in Medicine, 2021
Pruritus represents one of the most common symptoms in dermatology and general medicine. Chronic pruritus severely impairs the quality of life of affected patients.
Jana Maria Nemmer, Marcus Kuchner, Angeliki Datsi, Angeliki Datsi, Péter Oláh, Péter Oláh, Valérie Julia, Ulrike Raap, Bernhard Homey   +8 more
doaj   +1 more source

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +38 more
core   +1 more source

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

Interrelationship and Sequencing of Interleukins4, 13, 31, and 33 – An Integrated Systematic Review: Dermatological and Multidisciplinary Perspectives

Journal of Inflammation Research, 2022
Alin Laurentiu Tatu,1– 3,* Thomas Nadasdy,3,4 Anca Arbune,5,* Valentin Chioncel,6,* Carmen Bobeica,7 Elena Niculet,3,* Alina Viorica Iancu,7 Caterina Dumitru,8 Valentin Tudor Popa,3,9 Nicolas Kluger,10,11 Victor Gabriel Clatici,11 Claudiu
Tatu AL, Nadasdy T, Arbune A, Chioncel V, Bobeica C, Niculet E, Iancu AV, Dumitru C, Popa VT, Kluger N, Clatici VG, Vasile CI, Onisor C, Nechifor A   +13 more
doaj  

Elevated Interleukin-31 Levels in Serum, but Not CSF of Dogs with Steroid-Responsive Meningitis-Arteritis Suggest an Involvement in Its Pathogenesis

Animals, 2023
Steroid-responsive meningitis-arteritis (SRMA) is a predominantly Th-2 immune-mediated disease, but the exact pathomechanism remains unclear. Interleukin-31 (IL-31) is predominantly produced by T cells with a Th-2 phenotype during proinflammatory ...
Laura Lemke, Regina Carlson, Katrin Warzecha, Andrea V. Volk, Andrea Tipold, Jasmin Nessler   +5 more
doaj   +1 more source

Image_1_Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching.tif

, 2023
BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intermittent itchy rash. Type 2 inflammatory cytokines such as interleukin (IL)-4, IL-13, and IL-31 are strongly implicated in AD pathogenesis.
John McGrath (3801), Tomoko Kawaguchi (9368786), Kazue Uchida (12029727), Tomofumi Numata (12971504), Yuhki Yanase (3960317), Masataka Suehiro (17399263), Chie Ishikawa (84845), Nozomi Yanagida (17399266), Yozo Ishiuji (9378775), Ryo Saito (519632), Akio Tanaka (12544425)   +10 more
core   +1 more source

Image_2_Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching.tif

, 2023
BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intermittent itchy rash. Type 2 inflammatory cytokines such as interleukin (IL)-4, IL-13, and IL-31 are strongly implicated in AD pathogenesis.
John McGrath (3801), Tomoko Kawaguchi (9368786), Kazue Uchida (12029727), Tomofumi Numata (12971504), Yuhki Yanase (3960317), Masataka Suehiro (17399263), Chie Ishikawa (84845), Nozomi Yanagida (17399266), Yozo Ishiuji (9378775), Ryo Saito (519632), Akio Tanaka (12544425)   +10 more
core   +1 more source

Involvement of Leukotriene B4 Released from Keratinocytes in Itch-associated Response to Intradermal Interleukin-31 in Mice

Acta Dermato-Venereologica, 2017
A recent study suggests that interleukin-31 (IL-31) exerts its effect via indirect mechanisms rather than through direct stimulation of cutaneous nerves.
Tsugunobu Andoh, Ayako Harada, Yasushi Kuraishi   +2 more
doaj   +1 more source

The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma [PDF]

, 2015
Interleukin (IL)-31A binds to an heterodimer composed of IL-31 receptor A (IL-31RA) and Oncostatin M Receptor (OSMR). The IL-31/IL-31R complex is involved in the pathogenesis of various skin diseases, including cutaneous T-cell lymphoma.
Marimpietri, D., Corcione, A., E Ferretti, Fraternali Orcioni, G., Corcione A., RIBATTI, Domenico, S Zupo, Corrias, M., Fraternali Orcioni G, Ravetti JL, V Pistoia, Pistoia, V., Marimpietri D, G Fraternali-Orcioni, Pagnan G, TRIPODO, Claudio, Ravetti, J., G Pagnan, Guarnotta C, C Tripodo, D Ribatti, Pistoia V, Tripodo C, Pagnan, G., C Guarnotta, M V Corrias, J L Ravetti, Ferretti, E., Corrias MV, Zupo S, Ribatti, D., D Marimpietri, Zupo, S., GUARNOTTA, Carla, Ferretti E, A Corcione   +35 more
core   +1 more source

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]

, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core   +2 more sources