Results 21 to 30 of about 68,824,737 (161)

Interleukin-18 [PDF]

open access: yes, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B.   +2 more
core   +1 more source

Determination of Interleukin 31 (IL-31) serum levels according to severity of allergic rhinitis

open access: yesBangladesh Journal of Medical Science, 2015
Objective: This study was conducted to compare IL-31 serum levels in allergic rhinitis (AR) patients and normal controls as well as according to severity of AR. Materials and Methods: The subjects, normal controls and AR patients, were defined by history taking. Blood were collected from subjects and patients with AR. Serum was centrifuged and analyzed
Noor Suryani Mohd Ashari   +4 more
openaire   +2 more sources

Interleukin-31 Polymorphisms and Serum IL-31 Level in Patients with Mastocytosis: Correlation with Clinical Presen­tation and Pruritus

open access: yesActa Dermato Venereologica, 2017
Data on interleukin-31 (IL-31) involvement in the patho-genesis of mastocytosis, and its impact on pruritus development in the disease, are limited. The aim of this study was to analyse distinct IL-31 gene polymorphisms in 127 patients (age 0.5-76 years) with mastocytosis and their correlation with clinical presentation, pruritus and serum IL-31 levels.
Magdalena, Lange   +11 more
openaire   +3 more sources

Possible Role of Interleukin-31/33 Axis in Imatinib Mesylate-Associated Skin Toxicity

open access: yesTurkish Journal of Hematology, 2015
Imatinib mesylate is a small-molecule tyrosine kinase inhibitor (TKi) designed to target c-ABL and BCR-ABL, approved for the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors.
Caterina Musolino   +7 more
doaj   +1 more source

Interleukin-31 and Chronic Pruritus of Unknown Origin

open access: yesBiomarker Insights, 2020
Chronic pruritus of unknown origin (CPUO) is a refractory condition. The expression of Interleukin-31 (IL-31), a major pruritogenic cytokine, in CPUO patients has not been investigated.
Kanin Salao   +4 more
doaj   +1 more source

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes:the MRC-ILA Heart Study [PDF]

open access: yes, 2014
AIMS: Acute coronary syndromes (ACSs) are driven by inflammation within coronary plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel-response to injury. ACS patients have raised serum markers of inflammation.
Greenwood, J.P.   +30 more
core   +1 more source

Increased IL-31 expression in serum and tissue protein in prurigo nodularis

open access: yesTherapeutic Advances in Chronic Disease, 2022
Background: Prurigo nodularis (PN) is a chronic pruritic skin disease which can greatly impact patients’ quality of life. Moreover, the pathogenesis remains unclear, making it a difficult-to-treat condition.
Suteeraporn Chaowattanapanit   +8 more
doaj   +1 more source

IL-33 in Mental Disorders

open access: yesMedicina, 2021
Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo   +6 more
doaj   +1 more source

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

open access: yes, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core   +1 more source

Establishment of an Intradermal Canine IL-31-Induced Pruritus Model to Evaluate Therapeutic Candidates in Atopic Dermatitis

open access: yesVeterinary Sciences, 2023
Pruritic models in healthy dogs utilizing intravenous administration of interleukin 31 (IL-31) bypass the “natural” itch sensation in AD, which is initiated by pruriceptive primary afferent neurons in the skin.
Jason Pearson   +5 more
doaj   +1 more source

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