Results 211 to 220 of about 12,582,645 (332)

In vitro and in vivo evaluation of chemically synthesized, receptor-biased interleukin-4 and photocaged variants. [PDF]

Sci Adv
Ninomiya M, Egholm C, Breu D, Boyman O, Bode JW.   +4 more
europepmc   +1 more source

Transition Mutations of Interleukin-4 gene 590C>T in Patients with Type-2 Diabetes Mellitus

, 2019
Intisar Hussein Ahmed
openalex   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Genetic Deficiency of Interleukin-4 and Interleukin-13 Exacerbates Alcohol- and Cigarette Smoke-Associated Chronic Pancreatitis via the Pancreas-Intestine Axis. [PDF]

Gastro Hep Adv
Wang J, Shams Azar PR, Apte MV, Pandol SJ, Husain SZ, Lee B.   +5 more
europepmc   +1 more source

Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4. [PDF]

, 1992
Arnold E. Postlethwaite, M A Holness, Hitoshi Katai, Rajendra Raghow   +3 more
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis. [PDF]

Immunity
Das M, Alasharee M, Woods B, Mukherjee S, Kim S, Elkins M, Ngo J, Magin L, Timilshina M, Leyva-Castillo JM, Murphy KM, Anthony RM, Laureano AFS, Murphy GF, McNamee S, Brombacher F, Hogan SP, Turner JR, Abtahi S, Phipatanakul W, Leung DYM, Goleva E, Oettgen HC, Li M, Chou J, Schlievert PM, Finkelman FD, Geha RS.   +27 more
europepmc   +1 more source

Expression of interleukin-4, interleukin-9 and interleukin-13 in peripheral blood mononuclear cells of cystic fibrosis patients with and without allergy

, 2006
Patrick Daigneault, Qutayba Hamid, Hans‐Peter Hauber, Elias Matouk, Paque, France   +4 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor. [PDF]

PLoS Pathog
Volkening JD, Spatz SJ, Garcia M, Ross TA, Maekawa DA, Rosenthal KS, Zamora AC, Skipper A, Blakey JR, Paudel R.   +9 more
europepmc   +1 more source