Results 231 to 240 of about 14,230,992 (393)

Correction: A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor. [PDF]

PLoS Pathog
Volkening JD, Spatz SJ, Garcia M, Ross TA, Maekawa DA, Rosenthal KS, Zamora AC, Skipper A, Blakey JR, Paudel R.   +9 more
europepmc   +1 more source

Interleukin-4 (C590T) Gene Polymorphism in Association with Asthma Severity. [PDF]

J Asthma Allergy, 2023
Al-Ahmad M, Ali A, Haider MZ.
europepmc   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Mycobacterium tuberculosis Culture Filtrate Proteins plus CpG Oligodeoxynucleotides Confer Protection to Mycobacterium bovis BCG-Primed Mice by Inhibiting Interleukin-4 Secretion

, 2009
Denise Morais da Fonseca, Célio Lopes Silva, Pryscilla Fanini Wowk, Marina Oliveira e Paula, Simone G. Ramos, Cynthia Horn, G Marchal, Vânia Luiza Deperon Bonato   +7 more
openalex   +2 more sources

Systemic Interleukin-4 Application Promotes Functional Recovery and Reprograms Neuroinflammatory and Molecular Responses after Spinal Cord Injury in Rats. [PDF]

Theranostics
Alhalabi OT, Heene S, Zheng G, Heller R, Schubert T, Luzarowski M, Zha X, Walter J, Hansen-Palmus L, Biglari B, Wang XJ, Ruebenacker L, Skutella T, Kiening K, Schaaf CP, Krieg SM, Unterberg AW, Zweckberger K, Younsi A.   +18 more
europepmc   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

Leukemic cells from some adult T-cell leukemia patients proliferate in response to interleukin-4 [PDF]

, 1988
T. Uchiyama, M Kamio, T. Kodaka, S Tamori, S Fukuhara, Ryuichi Amakawa, Haruto Uchino, Keisuke Araki   +7 more
openalex   +1 more source

Inflammatory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4.

Immunity, 2013
Mayumi Egawa, K. Mukai, S. Yoshikawa, Misako Iki, N. Mukaida, Y. Kawano, Y. Minegishi, H. Karasuyama   +7 more
semanticscholar   +1 more source

Contribution of Interleukin-4 Promoter Genotypes to Gastric Cancer Risk in Taiwan. [PDF]

In Vivo
Fu CK, Lee HT, Yang YC, Chen JC, Yang MD, Wang YC, Shih HY, Tsai CW, Bau DT, Chang WS.   +9 more
europepmc   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source