Results 241 to 250 of about 705,101 (300)

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

Advanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen, Yi‐Fan Zhou, Xuan Qi, Ya‐Xin Zhao, Tong Fu, Xi Jin, Minhong Shen, Yi‐Zhou Jiang, Zhi‐Ming Shao   +8 more
wiley   +1 more source

Variation in Interleukin-4, -6, and -10 in Mastitis Milk: Associations with Infections, Pathogens, Somatic Cell Counts, and Oxidative Stress. [PDF]

Vet Sci
Chaisri W, Intanon M, Saipinta D, Srithanasuwan A, Pangprasit N, Jaraja W, Chuasakhonwilai A, Suriyasathaporn W.   +7 more
europepmc   +1 more source

Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers. [PDF]

Immunity
Shehata L, Thouvenel CD, Hondowicz BD, Pew LA, Pritchard GH, Rawlings DJ, Choi J, Pepper M.   +7 more
europepmc   +1 more source

Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder. [PDF]

Sci Rep
Sarmin N, Roknuzzaman ASM, Mouree TZ, Islam MR, Al Mahmud Z.   +4 more
europepmc   +1 more source

Long-term interleukin-4 release from 3D printable affinity hydrogels promotes M2-like macrophage polarisation <i>in vitro</i>.

Biomater Sci
Loxley GA, Coser C, Ghaemmaghami AM, Yang J.   +3 more
europepmc   +1 more source

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Interleukin 4

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1990
Since its discovery in 1982, numerous biological activities of interleukin-4 (IL-4) have been described. Like other cytokines, IL-4 is highly pleiotropic, both with respect to the number of different target cells that are responsive to it and with respect to the number of different biological responses it elicits.
J H, Jansen, W E, Fibbe, R, Willemze, J C, Kluin-Nelemans   +3 more
  +6 more sources

Interleukin‐4 and listeriosis

Immunological Reviews, 1997
Summary: Experimental infection of mice with Listeria monocytogenes (L. monocytogenes) has served as an appropriate model for analyzing Thl nil driven immune responses. Generally, Th2 responses are absent and IL‐4 is not detectable. Here, we describe experimental settings under which IL‐4 is detectable in listeriosis.
Kaufmann, S., Emoto, M., Szalay, G., Barsig, J., Flesch, I.   +4 more
openaire   +3 more sources

Rat interleukin-4 assays

Journal of Immunological Methods, 1998
The present article describes procedures to measure rat IL-4 protein. The RT-PCR technique has been successfully and widely used to measure IL-4 mRNA, but it does not determine IL-4 protein synthesis. Assays to measure rat IL-4 protein based on its biological activity were developed using the mAb OX-81, which inhibits rat IL-4 activity.
Ramírez, F., Stumbles, P.A., Puklavec, M., Mason, D.   +3 more
openaire   +2 more sources

Interleukin-4 and interleukin-4 receptor polymorphisms and colorectal cancer risk

European Journal of Cancer, 2007
Interleukin-4 (IL-4) and interleukin-4 receptor (IL-4R) modulate inflammation and are associated with the colorectal adenoma-carcinoma progression and the metastatic capacity. IL-4 also causes a dose-dependent reduction of proliferation in colorectal cancer cells.
LANDI, STEFANO, BOTTARI F, GEMIGNANI, FEDERICA, GIOIA PATRICOLA L, GUINO E, OSORIO A, DE OCA J, CAPELLA G, CANZIAN F, MORENO V.   +9 more
openaire   +2 more sources