Results 151 to 160 of about 79,526,962 (296)

Interleukine-5 [PDF]

médecine/sciences, 1990
openaire   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Cumulative corticosteroid-sparing effect of anti-interleukin-5/5Ra in eosinophilic asthma. [PDF]

Eur Respir J, 2022
Kroes JA, Zielhuis SWJ, De Jong K, Hashimoto S, Sont JK, Zielhuis SW, Van Roon EN, Bel EH, Ten Brinke A, RAPSODI Team.   +9 more
europepmc   +1 more source

Interleukin-5 from molecule to drug target for asthma

, 1999
This volume describes the latest advances in all areas of interleukin-5 (IL-5) research, pooling the insights of over 65 biological researchers, pharmaceutical scientists, and cliniciansFeaturing over 1250 references, tables, drawings, photographs, and ...
Sanderson, Colin J.
core  

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Development of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horses. [PDF]

Sci Rep, 2023
Langreder N, Schäckermann D, Meier D, Becker M, Schubert M, Dübel S, Reinard T, Figge-Wegener S, Roßbach K, Bäumer W, Ladel S, Hust M.   +11 more
europepmc   +1 more source

Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancer

, 2005
Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate ...
ED Williams (9893567), EW Thompson (14472741), A Hammacher (21767195)   +2 more
core  

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Effects of <i>Toxoplasma gondii</i> on Levels of Interleukin-5 in Parkinson's Patients. [PDF]

Arch Razi Inst, 2022
Hasan Kadhum Al-Huchaimi S, Hameed Neamah Al-Kefaei G, Ahmed Alameedy B.   +2 more
europepmc   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source