Results 161 to 170 of about 673,896 (307)

Interleukin-5, Eosinophil, and Immunoglobulin A Levels in Schizophrenia Patients. [PDF]

Alpha Psychiatry
Li X, Wang X, Zhou Q, Zhang Q, Pan S.
europepmc   +1 more source

Complete response to anti-interleukin-5 biologics in a real-life setting: results from the nationwide Danish Severe Asthma Register. [PDF]

ERJ Open Res, 2022
Soendergaard MB, Hansen S, Bjerrum AS, Hilberg O, Lock-Johansson S, Håkansson KEJ, Ingebrigtsen TS, Johnsen CR, Rasmussen LM, von Bülow A, Assing KD, Schmid JM, Ulrik CS, Porsbjerg C.   +13 more
europepmc   +1 more source

GSH‐Responsive Nanoparticles Enhance Hepatocellular Carcinoma Immunotherapy Through Synergistic Effects of Cuproptosis and PI3K Inhibitor Combination

Advanced Science, EarlyView.
ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu, Jintong Na, Xiyu Liu, Dongsheng Tang, Zhungang Yang, Zheng Cao, Xinyue He, Haihua Xiao, Liping Zhong, Yuan Liao, Yongxiang Zhao   +10 more
wiley   +1 more source

Straight to Phase III: Model-Informed Approach Speeds Depemokimab Clinical Development in Interleukin-5-Driven Diseases. [PDF]

Clin Pharmacol Ther
Zecchin C, Schalkwijk S, Pouliquen IJ, Berges A, Bird N, Follows R, Austin D.   +6 more
europepmc   +1 more source

Non-episodic angioedema with eosinophilia, with increased serum level of interleukin-5 in a young Japanese woman. [PDF]

Oxf Med Case Reports, 2022
Usami J.
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Persistent airway obstruction in severe eosinophilic asthma: targeting interleukin-5 and eosinophils. [PDF]

Eur Respir Rev
Hanania NA, Herth FJF.
europepmc   +1 more source

Localization and RNA Interference-Driven Inhibition of a Brugia malayi-Encoded Interleukin-5 Receptor Binding Protein. [PDF]

Infect Immun, 2022
Mejia R, Bennuru S, Oksov Y, Lustigman S, Munirathinam G, Kalyanasundaram R, Nutman TB.   +6 more
europepmc   +1 more source

Receptor-mediated gene transfer to airway epithelial cells in primary culture [PDF]

, 1993
Agarwal, Santosh, Curiel, David T., Harris, C. E., Hu, P.-C., Wagner, Ernst   +4 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source