Results 171 to 180 of about 79,526,962 (296)

Interleukin-5, Eosinophil, and Immunoglobulin A Levels in Schizophrenia Patients. [PDF]

Alpha Psychiatry
Li X, Wang X, Zhou Q, Zhang Q, Pan S.
europepmc   +1 more source

Th2 Cytokines (Interleukin-5 and -9) Polymorphism Affects the Response to Anti-TNF Treatment in Polish Patients with Ankylosing Spondylitis. [PDF]

Int J Mol Sci, 2022
Biały S, Iwaszko M, Świerkot J, Bugaj B, Kolossa K, Jeka S, Bogunia-Kubik K.   +6 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Straight to Phase III: Model-Informed Approach Speeds Depemokimab Clinical Development in Interleukin-5-Driven Diseases. [PDF]

Clin Pharmacol Ther
Zecchin C, Schalkwijk S, Pouliquen IJ, Berges A, Bird N, Follows R, Austin D.   +6 more
europepmc   +1 more source

Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells. [PDF]

Cardiovasc Res, 2023
Liu T, Meng Z, Liu J, Li J, Zhang Y, Deng Z, Luo S, Wang M, Huang Q, Zhang S, Fendt P, Devouassoux J, Li D, McKenzie ANJ, Nahrendorf M, Libby P, Guo J, Shi GP.   +17 more
europepmc   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Hypereosinophilia With Pseudomonas aeruginosa Infection in Patients With Asthma on Anti-Inteleurkin-5 Biologics. [PDF]

Chest
Rivard R, Mailhot-Larouche S, Borg C, Pujan P, Klein M, Lachapelle P, Couillard S.   +6 more
europepmc   +1 more source

Non-episodic angioedema with eosinophilia, with increased serum level of interleukin-5 in a young Japanese woman. [PDF]

Oxf Med Case Reports, 2022
Usami J.
europepmc   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

Advanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang, Tsz Kwan Yau, Joyce Tse, Tsz Ho Li, Dongjie Hu, Yong Juan Zhao, Ting‐Fung Chan   +6 more
wiley   +1 more source

Persistent airway obstruction in severe eosinophilic asthma: targeting interleukin-5 and eosinophils. [PDF]

Eur Respir Rev
Hanania NA, Herth FJF.
europepmc   +1 more source