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Mitogenic effects of interleukin-5 on microglia
Neuroscience Letters, 1995Interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte macrophage-colony stimulating factor (GM-CSF) are cytokines that bind to receptor complexes comprised of unique alpha-receptor subunits specific for each ligand and a commonly shared beta-receptor subunit.
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Measurement of Mouse and Human Interleukin 5
Current Protocols in Immunology, 1991AbstractTwo fundamentally different types of assays are available for quantitating interleukin 5 in biological samples. One type, a bioassay, is based on the ability of IL‐5 to enhance B cell proliferation and immunoglobulin secretion or eosinophil proliferation and differentiation.
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Interleukin 5 and B cell differentiation
Cytokine & Growth Factor Reviews, 1998Interleukin-5 (IL-5) stimulates proliferation and differentiation of B cells and eosinophils. IL-5 receptor (IL-5R) comprises alpha and (beta)c chains. IL-5 specifically binds to IL-5Ralpha and induces the recruitment of (beta)c to IL-5Ralpha. JAK2 and JAK1 tyrosine kinases are constitutively associated with hIL-5Ralpha and (beta)c, respectively and ...
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1995
Abstract The nucleotide sequence of the human IL-5Ra cDNA (GenBank accession numbers M75914, M96651, M96652, X61176, X61177, X61178, and X62156) predicts a polypeptide of 420 amino acids (Fig. 1) (Tavernier et al. 1991, 1992; Murata et al. 1992).
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Abstract The nucleotide sequence of the human IL-5Ra cDNA (GenBank accession numbers M75914, M96651, M96652, X61176, X61177, X61178, and X62156) predicts a polypeptide of 420 amino acids (Fig. 1) (Tavernier et al. 1991, 1992; Murata et al. 1992).
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Interleukins in cancer: from biology to therapy
Nature Reviews Cancer, 2021Peter Libby +2 more
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