Results 21 to 30 of about 9,333,661 (382)
Научно-практическая ревматология, 2023 Aim. Switching to another biologic with the same mode of action provides greater opportunity for long-term management of patients with rheumatoid arthritis (RA).
A. A. Baranov +16 more
doaj +1 more source
Paraneoplastic thrombocytosis in ovarian cancer [PDF]
, 2012 <p>Background: The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear.</p> <p>Methods: We analyzed clinical data on 619 patients with epithelial ...
Akl EA +35 more
core +1 more source
The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019
EMBO Molecular Medicine, 2020 Progression to severe disease is a difficult problem in treating coronavirus disease 2019 (COVID‐19). The purpose of this study is to explore changes in markers of severe disease in COVID‐19 patients.
Tao Liu +12 more
semanticscholar +1 more source
Role of Interleukin-6 in Depressive Disorder
International Journal of Molecular Sciences, 2020 Major depressive disorder (MDD), which is a leading psychiatric illness across the world, severely affects quality of life and causes an increased incidence of suicide.
Emily Yi-Chih Ting, A. Yang, S. Tsai
semanticscholar +1 more source
Expression of interleukin-6 and interleukin-6 receptor in Hodgkin's disease [PDF]
Blood, 1991 Interleukin-6 (IL-6) is a multipotent lymphokine that can mediate differentiation of B cells into Ig-secreting cells, stimulate the growth of plasmacytomas, hybridomas, and T cells, and induce acute- phase proteins in liver cells. It has been suggested that IL-6 is involved in the pathogenesis of several diseases by autocrine or paracrine pathways.
H Merz +9 more
openaire +4 more sources
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
, 2012 BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza +4 more
core +1 more source
Repurposing Interleukin-6 Inhibitors to Combat COVID-19. [PDF]
, 2020 Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a pandemic with major implications across the world. One of the most frequent causes of death from SARS-CoV-2 is fatal pneumonia from coronavirus disease 2019 (COVID-19), which is associated
Kato, Shumei, Kurzrock, Razelle
core +1 more source
Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome
Mediators of Inflammation, 2006 The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic +5 more
doaj +2 more sources
Interleukin‐6: a cytokine to forget [PDF]
The FASEB Journal, 2004 ABSTRACTIt is known that proinflammatory cytokines such as interleukin‐6 (IL‐6) are expressed in the central nervous system (CNS) during disease conditions and affect several brain functions including memory and learning. In contrast to these effects observed during pathological conditions, here we describe a physiological function of IL‐6 in the ...
Balschun, Detlef +6 more
openaire +4 more sources
Historical overview of the interleukin-6 family cytokine
Journal of Experimental Medicine, 2020 Kishimoto and colleagues present an overview of the complex biology of interleukin-6 family cytokines, focusing on signaling transduction of the receptor molecule.
Sujin Kang +3 more
semanticscholar +1 more source