Results 51 to 60 of about 382,334 (303)
Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]
, 2002 Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.Humphries, S.E., Rumley, A., Lowe, G.D., Montgomery, H.E., Sanders, J., Brull, D.J. +5 morecore Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceOncolytic Effects of a Novel Influenza A Virus Expressing Interleukin-15 from the NS Reading Frame
, 2012 Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway.Martin Michaelis, Muster Thomas, Joachim Seipelt, Markus Wolschek (167359), Martin Michaelis (23843), Marijke van Rikxoort (167355), Doerr, Hans Wilhelm, Wolschek Markus, Seipelt Joachim, Hans Wilhelm Doerr (17928), Andrej Egorov (167364), Thomas Muster, Hans Wilhelm Doerr, Jindrich Cinatl, Thomas Muster (167361), Muster, Thomas, Doerr Hans Wilhelm, Seipelt, Joachim, Joachim Seipelt (30928), Egorov Andrej, Cinatl Jindrich, Michaelis, Martin, Cinatl, Jindrich, Egorov, Andrej, Markus Wolschek, van Rikxoort, Marijke, Rikxoort, Marijke van, Andrej Egorov, van Rikxoort Marijke, Jindrich Cinatl Jr (167368), Wolschek, Markus, Marijke van Rikxoort, Michaelis Martin +32 morecore +1 more sourceCardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist : a Mendelian randomisation analysis [PDF]
, 2015 Funded by: UK Medical Research Council, British Heart Foundation, UK National Institute for Health Research, National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council, and European Commission Framework ...D. F. Easton (7608179), Howson, Joanna M M, Singleton, A, E. Harshfield (7646096), Sanna, Serena, Hall, A.S. (Alistair), Bown, Matthew J, Stefánsson, K., Staley, James R, Dunlop, M., Rasmussen-Torvik, L.J. (Laura), B. G. Nordestgaard (7605362), Langefeld, C.D. (Carl), Grande, P, Sanna, S., Smith, AV, G. F. Mitchell (7646183), Kooner, J.S. (Jaspal S.), Felix, J.F., Gudnasson, Vilmundur, Carrell, D. S., McCarty, Catherine A., D. Crossman (7646276), Hakonarson, Hakon, Franco, O.H., Stefansson, K, Nelson, C.P. (Christopher P.), Walston, J. (Jeremy), Eisen, T. (Timothy), Hofman, A., Crosslin, D.R., Assimes, T, D. T. Bishop (7646264), Stefánsson, Kári, de Bakker, Paul I. W., Gorski, M. (Mathias), Malinowski, J. (Jennifer), G. Tromp (7646132), Li, Yong, Goldschmidt, Hartmut, Y. Wang (473169), M. Sudman (7646219), Ferreira, MA, Crawford, DC, Weidinger, S., T. Kessler (7646111), Nielsen, SF, E. Di Angelantonio (7611773), McCarty, C.A. (Catherine A.), O. Gottesman (7646165), März, Winfried, Gorski, Mathias, Hall, AS, J. R. Staley (7646090), Iles, M.M., Hayward, NK, Hopewell, J. C., Peissig, P.L., Brown, Matthew J., Bevan, S, P. Willeit (7605167), Nordestgaard, B.G., L. A. Lange (7646105), Kessler, Thorsten, Delgado, G.E., Law, M. H., Delgado, G., Franceschini, N. (Nora), Nalls, M.A., Zhang, W., Hopewell, Jemma C., Harshfield, E, Delgado, G. E., Franco, O. H., N. J. Timpson (7608851), Tracy, Russell, Franceschini, N, Delgado, GE, H. Baurecht (7646204), M. de Andrade (7646150), Butterworth, Adam S, Bown, M.J., Polychronakos, C. (Constantin), Kooner, J.S., Schunkert, H, A. F. Baas (7646126), Li, Yunlei, Nalls, M.A. (Michael), N. J. Samani (7591811), Peissig, Peggy L., Bown, MJ, de Andrade, Mariza, Wareham, N.J., Nelson, CP, Scott, Robert A., Li, Y., Nejentsev, S., Allan, JM, M. Gorski (7626956), Evans, D.M. (David M.), Van 'T Hof, F.N.G. (Femke), A. A. S. Majumder (7646297), Erdmann, Jeanette, Samani, N. J., Rader, D.J. (Daniel), Harshfield, E., Houlston, R.S., Delgado, Graciela E., S. S. Verma (7646141), Franke, Andre, E. Zeggini (7632767), Zhang, WH, A. Singleton (7646228), Polychronakos, C, Franke, A, U. Thorsteinsdottir (7606031), S. G. Thompson (7646303), M. F. Keller (7646189), J. P. Bradfield (7646234), de Bakker, Paul I W, Allan, J. M., van 't Hof, Femke N. G., D. Chubb (7646255), Nikpay, Majid, M. A. Brown (1916698), Dehghan, Abbas, J. S. Kooner (7605356), Eisen, T, Chubb, Daniel, Harshfield, Eric, Whiffin, N, Freitag, Daniel, H. S. Markus (7626758), Tomlinson, I.P., Goldschmidt, H, Erdmann, J, Baas, A.F., Lange, Leslie A., Nielsen, S. F., Weidinger, S. (Stephan), Farrall, M. (Martin), Kuivaniemi, Helena, Ganesh, Santhi K., Reilly, Muredach, März, W. (Winfried), Huang, J., C. P. Nelson (7591670), Qu, Liming, Thorsteinsdottir, U, Wood, Angela M., De Andrade, M, Ritchie, M.D., Gottesman, O., Kastrati, A, Young, R. (Robin), J. M. Allan (7646246), Young, R., Müller-Nurasyid, M., van ‘t Hof, Femke N.G., Thorsteinsdottir, U. (Unnur), Psaty, B. M., J. Malinowski (7646147), Mueller-Nurasyid, M, Psaty, B.M. (Bruce), Easton, Douglas F., Hakonarson, H, Burgess, S, Ramond, A. (Anna), Marz, W, Luo, Y. (Yang), Pacheco, Jennifer A., Ritchie, Marylyn D., Carrell, D.S. (David), Howson, Joanna M.M., Ho, W.K., Kathiresan, S. (Sekar), S. A. Lubitz (7646210), Spackman, S, Smith, Nicholas L., Hemminki, Kari, Burgess, Stephen, D. C. Crawford (7646144), S. Nejentsev (7646273), D. Thompson (1262301), S. F. Nielsen (7646099), Bevan, S., Kooner, J. S., van 't Hof, F.N.G., Langefeld, Carl D., Lange, Leslie A, Lubitz, S.A. (Steven), Harris, T.B. (Tamara B.), Thompson, D., Sweeting, M, Iles, MM, Bown, M.J. (Matthew), M. Reilly (7609133), Ho, WK, Houlston, Richard S., Houlston, R. S., Ala-Korpela, M. (Mika), Li, Y. (Yong), Verma, S. S., Gottesman, Omri, A. Parsa (7626662), S. D. Thompson (7646222), Tomlinson, I.P. (Ian), J. Kettunen (7646180), Markus, H. S., Franco, O.H. (Oscar), Baas, A. F., Psaty, Bruce M., Ferreira, Manuel A., Jones, G. T., Grande, Peer, Smith, N.L., Al Shafi Majumder, A. (Abdullah), Law, MH, Wang, YF, S. Spackman (7646087), A. V. Smith (7605131), Hemminki, Kari,, Hall, A. S., Dunlop, Malcolm, Panoutsopoulou, K. (Kalliope), Howson, J. M. M., M. M. Iles (7646261), Allan, J.M., Tybjaerg-Hansen, A. (Anne), J. C. Bis (7625957), Ferreira, M.A., Freitag, DF, Matthew James Bown (7632455), Allan, James M., Jones, G.T., Wang, Y., Y. Li (696089), Franke, A., Parsa, Afshin, Bis, J.C. (Joshua), Hall, Alistair S., Farrall, M, Barbalic, M., Gottesman, R.F. (Rebecca), Hayward, N. K., Crosslin, D. R., van Rij, A., Staley, James R., Collins, F.S. (Francis), Porcu, E., Pacheco, J. A., Wang, Y, Lange, L. A., Henrion, Marc, Keller, MF, Zeggini, E, Crosslin, DR, S. Bevan (7626584), Parsa, A., Franco, Oscar H., Bown, Matthew J., Lange, LA, Bradfield, J.P. (Jonathan), Bottinger, EP, Smith, A.V., Lubitz, S.A., Qu, LM, Erdmann, J. (Jeanette), Angelantonio, E.D. (Emanuele Di), Crossman, D, W. K. Ho (7646081), Franceschini, N., Nalls, M. A., Thompson, S.D. (Susan D.), Wood, Angela M, Nelson, C. P., Keller, M. F., Scott, R.A. (Robert), Mitchell, GF, Langefeld, C.D., Qu, L., Smith, N.L. (Nicholas), Bis, J.C., Samani, N.J., Luo, Yang, Rader, Daniel J., Kathiresan, S, Walston, Jeremy D., Soranzo, N., Butterworth, A.S. (Adam), Crossman, D. (David), Collins, R, Sweeting, M., Porcu, E. (Eleonora), Burgess, S. (Stephen), Watkins, H. (Hugh), Hayward, N.K., Baurecht, H. (Hansjörg), Burgess, S., Markus, HS, Freitag, Daniel F., Iles, M. M., W. Zhang (820655), Rasmussen-Torvik, L.J., Thompson, D. (Deborah), Wood, A.M., Kleber, M.E. (Marcus), Tracy, R.P. (Russell), Bis, Joshua C., Huang, Jie, L. Qu (822458), Collins, R., Farrall, M., Li, Y, Hayward, Nicholas K., Parsa, A, Young, Robin, Easton, D. F., Chubb, D., Kullo, Iftikhar J., B. M. Psaty (7605224), A. S. Hall (7605176), Clarke, R. (Robert), D. Saleheen (7605173), Porcu, Eleonora, Grande, P. (Peer), Zeggini, E. (Eleftheria), Zeng, L, N. Soranzo (7608857), Chambers, J.C., M. Nikpay (7646114), L. J. Rasmussen-Torvik (7646174), J. C. Chambers (7605185), Iles, Mark M., K. Panoutsopoulou (7632989), M. Barbalic (7605845), Mitchell, Gary F., Nordestgaard, BG, Porcu, E, Kaptoge, Stephen, Lange, L.A. (Leslie), Crosslin, David R., Parsa, A. (Afshin), Soranzo, Nicole, Hofman, A. (Albert), Chambers, J.C. (John C.), J. A. Pacheco (7646177), O Reilly, M, Maerz, W, S. Weidinger (7646207), Morgan, G., Whiffin, Nicola, Scott, Robert A, Howson, Joanna M. M., Ganesh, S.K. (Santhi), Ala-Korpela, Mika, Scott, RA, Young, R, Müller-Nurasyid, Martina, Bishop, D.T., Jones, G.T. (Gregory), Crossman, David, H. Kuivaniemi (7646135), Kooner, Jaspal S., Willeit, Peter, de Bakker, Paul I.W., Kooner, JS, Tybjaerg-Hansen, Anne, Wang, Yufei, Nelson, C.P., Nordestgaard, Borge G., S. Baltic (7646198), Thorleifsson, Gudmar, Watkins, Hugh, Harris, T. B., D. S. Carrell (7646171), Thompson, D, F. N. G. van 't Hof (7646123), Malinowski, Jennifer, Walston, J.D., C. Polychronakos (7646231), J. D. Walston (7646291), A. S. Butterworth (7605158), Howson, J.M.M. (Joanna M.M.), Schunkert, Heribert, Saleheen, Danish, van 't Hof, Femke N G, Lange, L.A., Wilkinson, Ian B., Spackman, Sarah, N. J. Wareham (7608962), Baurecht, Hansjörg, Bradfield, Jonathan P., T. Assimes (7646279), Kathiresan, Sekar, Panoutsopoulou, K., Markus, Hugh S., Carrell, DS, Ferreira, M. A., Verma, Shefali S., Ferreira, M.A. (Manuel), Goel, A. (Anuj), M. Sweeting (7646084), van 't Hof, F. N. G., J. Erdmann (7603664), G. Morgan (1390121), Sanna, S. (Serena), Eisen, Timothy, Peissig, P. L., Easton, D.F., Wilkinson, IB, Markus, H.S. (Hugh), Freitag, D., Ramond, A., H. Goldschmidt (5077982), Jones, GT, Morgan, G, G. E. Delgado (7646117), Tromp, G. (Gerard), Luo, Y, Hopewell, J.C., Ligthart, S. (Symen), Panoutsopoulou, Kalliope, McPherson, R., Alam, Dewan S., Thompson, SD, Timpson, N.J., A. Ramond (7646093), Thompson, SG, R. Do (7605920), D. F. Freitag (7605161), Thompson, Simon G., Ritchie, M. D., Rasmussen-Torvik, Laura J., Samani, NJ, Danesh, J, E. Porcu (3354512), I. J. Kullo (7646153), Chowdhury, R., Zeng, L. (Lingyao), Wilkinson, I. B., Goldschmidt, H. (Hartmut), Kathiresan, S., Bottinger, E.P. (Erwin), I. B. Wilkinson (7646186), Kettunen, Johannes, A. van Rij (7646129), T. Eisen (7646243), Thompson, S. G., Nikpay, M., Tybjærg-Hansen, Anne, Sanna, S, D. M. Evans (7624460), de Bakker, P.I.W., S. Ligthart (7646120), Bishop, D. Timothy, Nalls, Mike A., Chubb, D, Baltic, Svetlana, Bishop, DT, Goel, A, Assimes, T.L. (Themistocles), Franco Duran, OH, Qu, L, Mitchell, G.F. (Gary), Chubb, D. (Daniel), Alam, D.S. (Dewan S.), M. H. Law (7646267), M. D. Ritchie (7646138), Müller-Nurasyid, M. (Martina), Thorleifsson, G. (Gudmar), S. Sanna (7609256), Walston, J. D., Eisen, T., Polychronakos, Constantin, Muller-Nurasyid, M, Butterworth, Adam S., Crawford, D. C., Zhang, W, Bishop, D.T. (David Timothy), Evans, DM, Butterworth, AS, Bis, JC, Pacheco, J.A., Nordestgaard, Børge G., Zeng, Lingyao, Goel, Anuj, M. Farrall (6522599), Watkins, H., Hayward, N. (Nick), Felix, JF, M. Dunlop (7596542), A. M. Wood (7642988), Howson, J.M.M., K. Hemminki (7646240), Danesh, J., Grande, P., Langefeld, CD, Thompson, S.G., Hemminki, K., Rasmussen-Torvik, LJ, Keller, Margaux F., Singleton, Andrew, ?, ?, Kleber, M, Saleheen, D, Boettinger, EP, Wood, AM, Kettunen, J. (Johannes), Nikpay, M. (Majid), Crawford, D.C. (Dana), G. Thorleifsson (7606022), Zwart, J-A. (John-Anker), Nikpay, M, Felix, Janine, Keller, M.F., Böttinger, E.P., Thompson, S. D., Hakonarson, H., T. B. Harris (7605353), Ritchie, M.D. (Marylyn D.), Soranzo, N. (Nicole), N. Franceschini (7625954), Weidinger, Stephan, Baurecht, Hansjoerg, Peissig, PL, Staley, J. R., R. A. Scott (2840021), Pacheco, J.A. (Jennifer A.), Felix, J. F., Tracy, R., Brown, MA, Di Angelantonio, E, R. S. Houlston (7646258), Wareham, N.J. (Nick), Bakker, P.I.W. (Paul) de, Crawford, D.C., Lubitz, Steven A., Huang, J, Alam, D. S., Franco, OH, Gudnason, V. (Vilmundur), Kullo, I.J., M. Mueller-Nurasyid (7646213), Do, Ron, Kleber, Marcus, Schunkert, H., Reilly, M.P. (Muredach), Tomlinson, Ian P., Reilly, M, Kessler, T. (Thorsten), Franceschini, Nora, Goel, A., McPherson, R. (Ruth), Ritchie, MD, McCarty, C.A., Qu, L. (Liming), J. M. M. Howson (7646075), D. S. Alam (7646294), N. L. Smith (7646216), Al Shafi Majumder, A., Spackman, S., Erdmann, J., Ligthart, Symen, Reilly, M., Chambers, J. C., E. P. Boettinger (7646162), Law, M.H., Nielsen, Sune F, Felix, Janine F., M. Kleber (7609331), Lund University., Butterworth, A.S., Carrell, David S., Willeit, J. (Johann), Scott, R. A., McPherson, R, Nelson, Christopher P., Sudman, M., Henrion, M, Bevan, Steve, Gudnason, V, Staley, J.R., Malinowski, J., Wang, Y. (Yufei), S. Kathiresan (7606013), Dehghan, A., S. Burgess (4176619), Whiffin, N., Wareham, N. J., Bown, M. J., Wareham, NJ, Kessler, T., Sweeting, M. (Michael), Sudman, Marc, Smith, Albert V., Chambers, John C., Bradfield, J. P., Tybjaerg-Hansen, A, J. C. Hopewell (7605365), Felix, J.F. (Janine), L. Zeng (7646108), Lubitz, SA, M. A. Nalls (7646225), Scott, R.A., Markus, H.S., van Rij, Andre, Samani, N.J. (Nilesh), Harris, TB, Freitag, C.M. (Christine), A. Goel (7602413), Kullo, IJ, Franke, A. (Andre), Wareham, Nicholas J., Saleheen, D., Ramond, A, Kathiresan, Sekhar, Jones, Gregory T, Sweeting, Michael, Ligthart, S., Barbalic, Maja, Collins, Rory, Rader, DJ, Timpson, Nicholas J., Smith, A.V. (Davey), Hofman, Albert, Henrion, M., D. R. Crosslin (7646168), G. T. Jones (7627466), Thompson, Deborah, Ganesh, S.K., Wilkinson, I.B., Evans, David M., Tromp, G, Bruijn, L., Nejentsev, S. (Sergey), Kuivaniemi, H., Majumder, Abdullah Al Shafi, Do, R. (Ron), Nordestgaard, B. G., K. Stefansson (7606001), Gorski, M, Al Shafi Majumder, Abdullah, Kettunen, J, Majumder, AAS, M. Ala-Korpela (3442535), Gottesman, O, Assimes, T., McCarty, C. A., Barbalic, M, R. Clarke (7602407), Rasmussen-Torvik, L. J., Walston, JD, Whiffin, N. (Nicola), Tomlinson, IP, Willeit, P, Evans, D.M., Bruijn, Lucie, Nielsen, S.F., Morgan, G. (Gareth), de Bakker, P. I. W., Gudnason, V., Bis, J. C., Tracy, R, Baurecht, H, Polychronakos, C., Nielsen, S.F. (Sune), Bruijn, L. (Lucie), Böttinger, E. P., Bevan, S. (Steve), Kullo, I. J., De Bakker, PIW, McCarty, CA, Mitchell, G. F., Bishop, D. T., Carrell, D.S., Weidinger, S, Mueller-Nurasyid, Martina, Ala-Korpela, M., Samani, Nilesh J., M. A. Ferreira (7646201), J. Danesh (7605383), Hofman, Bert, Law, M.H. (Matthew H.), Watkins, H, Singleton, A., Huang, J. (Jie), Zhang, W. (Weihua), Mitchell, G.F., Van 't Hof, FNG, Nielsen, Sune F., Thompson, Susan D., Barbalic, M. (maja), Malinowski, J, Majumder, AA, Willeit, P., Soranzo, N, I. P. Tomlinson (7646237), Di Angelantonio, Emanuele, Dehghan, A, Li, Yunlei; id_orcid, Baas, A.F. (Annette), Easton, DF, Luo, Y., Staley, JR, A. Tybjaerg-Hansen (7605182), Kaptoge, S., Smith, N. L., Baurecht, H., Kleber, M., Hemminki, K, Zeggini, Eleftheria, Hemminki, K. (Kari), Dunlop, M, Sudman, M. (Marc), Kuivaniemi, H, Angelantonio, Emanuele Di, A. Dehghan (7626011), Brown, M.A. (Matthew), Ho, Weang Kee, Keller, M.F. (Margaux), Kaptoge, S, Baas, Annette F., Henrion, M. (Marc), Kessler, T, Rij, A.M. (Andre) van, Staley, J.R. (James R.), Peissig, P.L. (Peggy L.), Harris, T.B., Chowdhury, Rajiv, M. Henrion (7646249), Clarke, Robert, Chambers, JC, Ramond, Anna, Andrade, M. (Mariza) de, Baltic, S, Boettinger, Erwin P., Alam, D.S., L. Bruijn (7646195), Nejentsev, Sergey, Baltic, S. (Svetlana), Clarke, R., Thorsteinsdottir, Unnur, Kuivaniemi, H. (Helena), Chowdhury, R. (Rajiv), de Andrade, M., Angelantonio, E. D., W. Maerz (7646285), Kullo, I. (Iftikhar), Crossman, D., Hakonarson, H. (Hakon), Wilkinson, I.B. (Ian B.), Tromp, G., Ligthart, S, H. Schunkert (7603670), Tromp, Gerard, S. Kaptoge (7605374), Dunlop, M. (Malcolm), Gorski, M., Böttinger, Erwin P., Pacheco, JA, Harris, Tamara B., P. I. W. de Bakker (7605305), Timpson, N. J., Crosslin, D.R. (David), Bradfield, J.P., Thorleifsson, G, Timpson, NJ, Law, Matthew H., Nordestgaard, B.G. (Børge), Gudnason, Vilmundur, Bradfield, JP, H. Hakonarson (7609127), N. K. Hayward (7646270), Goldschmidt, H., Singleon, Andrew, P. Grande (7646102), Farrall, Martin, Wood, A. M., V. Gudnason (7605347), Crawford, Dana C., Do, R, Verma, S.S., Houlston, RS, Morgan, Gareth, Singleton, A. (Andrew), J. F. Felix (7625948), R. Collins (7159586), Zeng, LY, Clarke, R, Thompson, S.D., A. Franke (7412741), Dehghan, A. (Abbas), Van Rij, A, Smith, A. V., Rader, D.J., Panoutsopoulou, K, Tybjærg-Hansen, A., Bruijn, L, Nalls, MA, Kastrati, Adnan, S. K. Ganesh (7626842), Angelantonio, E.D., Baltic, S., R. Tracy (7646282), Danesh, John, A. Kastrati (7646288), Thorsteinsdottir, U., Easton, D.F. (Douglas), Harshfield, E. (Eric), Kastrati, A. (Adnan), Verma, SS, Zeng, L., März, W., Howson, JMM, Thorleifsson, G., Iles, M.M. (Mark M.), R. McPherson (7605974), Spackman, S. (Sarah), Do, R., Rader, D. J., D. J. Rader (7605215), R. Chowdhury (7646300), Danesh, J. (John), R. Young (7646078), P. L. Peissig (7646156), Brown, Matthew A., Psaty, BM, Verma, S.S. (Shefali S.), Zeggini, E., Schunkert, H. (Heribert), Thompson, S.G. (Simon), McPherson, Ruth, Chowdhury, R, J. Huang (2342368), Jones, Gregory T., Smith, NL, Psaty, B.M., Assimes, Themistocles, Zhang, Weihua, O. H. Franco (7625993), Brown, M.A., Hofman, A, A. Hofman (4269889), Hopewell, Jemma C, H. Watkins (7602419), Kastrati, A., Hall, A.S., Wood, A.M. (Angela), Ala-Korpela, M, C. D. Langefeld (7646192), Ho, W. K., Ganesh, S. K., Lubitz, S. A., Hopewell, JC, Nejentsev, S, Y. Luo (1398985), Maerz, Winfried, Baas, AF, C. A. McCarty (7646159), N. Whiffin (7646252), Hopewell, J., Houlston, R. (Richard), Timpson, N.J. (Nicholas), Allan, J.M. (James), Alam, DS, Kaptoge, S. (Stephen), Delgado, Graciela E, Ho, W.K. (Weang Kee), Sudman, M, Thorsteindottir, Unnur, Kettunen, J., Langefeld, C. D., Tomlinson, I. P., Ganesh, SK +874 morecore +1 more sourceReciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.Marie Déborah Bancilhon, Bruno Mesminwiley +1 more sourceEffects of BET Inhibitor JQ1 and Interleukin-6 on Breast Cancer Cells [PDF]
, 2021 Abstract Bromodomain and extra-terminal (BET) proteins are recognized acetylated lysine of histone 4 and act as scaffolds to recruit many other proteins to promoters and at enhancers of active genes, especially at the super-enhancers of key genes, driving the transcription process and have been identified as potential therapeutic targets in ...Atefeh Sharif Hoseini, Masoud Heshmati, Amin Soltani, Hedayatollah Shirzad, Morteza Sedehi, Barbi A Judd, Mohammad-Saeid Jami, Mahdi Ghatreh Samani +7 moreopenaire +1 more sourceNetwork divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers +9 morewiley +1 more sourceEndothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside‐Containing Nanoliposomes
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content between ...Nina Karamanova, Seth Truran, Geidy E. Serrano, Thomas G. Beach, Jillian Madine, Volkmar Weissig, Hannah A. Davies, Jaimeson Veldhuizen, Mehdi Nikkhah, Michael Hansen, Weiyang Zhang, Karen D'Souza, Daniel A. Franco, Raymond Q. Migrino +13 moredoaj +1 more source
