Results 31 to 40 of about 382,334 (303)

Platelet Microvesicles, Inflammation, and Coagulation Markers: A Pilot Study

Hematology Reports, 2023
Background: Platelet “Microvesicles” (MVs) are studied for their role in blood coagulation and inflammation. The study aimed to establish if MVs are related to age, plasma levels of inflammation, coagulation, and fibrinolysis markers in healthy ...
Antonio Gidaro, Alessandro Palmerio Delitala, Roberto Manetti, Sonia Caccia, Mark J. Soloski, Giorgio Lambertenghi Deliliers, Dante Castro, Mattia Donadoni, Arianna Bartoli, Giuseppe Sanna, Luigi Bergamaschini, Roberto Castelli   +11 more
doaj   +1 more source

The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]

, 2002
In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Dolmans, Wil M.V., van der Meer, Jos W. M., Wil Dolmans, Setiati, T.E., Dolmans, W.M.V., C. Hack, Jos van der Meer, Hugo ten Cate, Hack, C. Erik, Hack, C.E., Djokomoeljanto, R.J., Cate, H. ten, Djokomoeljanto, Robert J., Cate, Hugo ten, Suharti, C., Catharina Suharti, Djokomoeljanto, Robert J., Gorp, E. van, Meer, J.W.M. van der, Dolmans, Wil M. V., Setiati, Tatty E., Meer, Jos W.M. van der, Eric van Gorp, Napel, C.H.H. ten, Gorp , Eric C.M. van, ten, Cate Hugo, Suharti, Catharina, Setiati , Tatty E., Robert Djokomoeljanto, Gorp, E.C.M. van, van Gorp, Eric C. M., Tatty Setiati   +31 more
core   +1 more source

Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice

Neurobiology of Disease, 2007
Epidemiological and experimental data implicate maternal–fetal infection and an associated increase in circulating cytokines in the etiology of cerebral palsy.
Géraldine Favrais, Leslie Schwendimann, Pierre Gressens, Vincent Lelièvre   +3 more
doaj   +1 more source

Effects of biomarkers secreted by visceral adipocites on the cardiovascular system

Атеросклероз, 2020
The literature review highlights the results of recent studies of the world over the invectigations of biochemical factors secreted by visceral adipocytes and affecting the activity of the cardiovascular system.
V. I. Oblaukhova, Yu. I. Ragino
doaj   +1 more source

Tocilizumab for COVID-19: A systematic review and meta-analysis of randomized controlled trials

Monaldi Archives for Chest Disease, 2022
The effective treatment modalities for severe coronavirus disease 2019 (COVID-19) are needed. As the primary cause of mortality is a hyperinflammatory state, the interleukin-6 antagonist tocilizumab has been used in multiple clinical studies.
Tarun Krishna Boppana, Saurabh Mittal, Karan Madan, Anant Mohan, Vijay Hadda, Randeep Guleria   +5 more
doaj   +1 more source

Interleukin 6 Receptor Inhibitor Levilimab in the Treatment of Rheumatoid Arthritis

Effective Pharmacotherapy, 2022
The inhibitors of the biological effects of interleukin 6 (IL-6) are the most actively developing group of biologics for the treatment of rheumatoid arthritis (RA) due to pleiotropic effects of this most important pro-inflammatory cytokine, which stimulates a number of processes that play an important role in the pathogenesis of RA.
D.E. Karateev, E.L. Luchikhina
openaire   +1 more source

The Role of Interleukin-6 Inhibitors in the Treatment of COVID-19 Infections: A Case Series [PDF]

Cureus, 2020
An outbreak of severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) infection started in December 2019 in China that resulted in a global health emergency. The World Health Organization later named the disease as coronavirus disease 2019 (COVID-19).
Tadepalli, Satish, Vanjarapu, Jagan Mohan Rao, De Dona, Anna, Cheriyath, Pramil, Nookala, Vinod   +4 more
openaire   +2 more sources

A Recovered Case of COVID-19 Myocarditis and ARDS Treated With Corticosteroids, Tocilizumab, and Experimental AT-001

JACC: Case Reports, 2020
We describes a case of a critically ill patient with myocarditis and severe acute respiratory distress syndrome related to coronavirus disease-2019.
Justin Coyle, DO, Efehi Igbinomwanhia, MD, MPH, Alejandro Sanchez-Nadales, MD, Sorin Danciu, MD, MS, Chae Chu, MD, Nishit Shah, MD   +5 more
doaj   +1 more source

Successful Use of Higher-Dose Etanercept for Multirefractory Systemic Flare of Adult-Onset Still’s Disease with Liver Failure with No Response to Tocilizumab Therapy

Case Reports in Rheumatology, 2013
A 21-year-old woman with refractory systemic flare of adult-onset Still’s disease with liver failure despite high-dose corticosteroids, cyclosporine, tacrolimus, and tocilizumab, was successfully treated with additional use of etanercept. Etanercept at a
Taio Naniwa, Shinya Tamechika, Shiho Iwagaitsu, Shinji Maeda, Hiroyuki Togawa   +4 more
doaj   +1 more source

Peripheral Blood Biomarkers for Early Diagnosis, Severity, and Prognosis of Checkpoint Inhibitor-Related Pneumonitis in Patients With Lung Cancer

Frontiers in Oncology, 2021
BackgroundCheckpoint inhibitor-related pneumonitis (CIP) is a potentially fatal immune-related adverse event that occurs during treatment with immune checkpoint inhibitors (ICIs).
Xinqing Lin, Haiyi Deng, Yilin Yang, Jianhui Wu, Guihuan Qiu, Suyang Li, Xiaohong Xie, Ming Liu, Zhanhong Xie, Yinyin Qin, Yong Song, Chengzhi Zhou   +11 more
doaj   +1 more source