Circulation Research, 2016 Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) predict vascular risk with an effect estimate as large as that of total or high-density lipoprotein cholesterol.
P. Ridker
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao +5 more
wiley +1 more source
Predictive Value of Soluble CD14, Interleukin-6 and Procalcitonin For Lower Extremity Amputation in People with Diabetes with Foot Ulcers: A Pilot Study [PDF]
, 1969 Ahmet Karakaş +6 more
openalex +1 more source
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases.
Blood, 2011 More than any other cytokine family, the IL-1 family of ligands and receptors is primarily associated with acute and chronic inflammation. The cytosolic segment of each IL-1 receptor family member contains the Toll-IL-1-receptor domain.
C. Dinarello
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf +6 more
wiley +1 more source
Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production [PDF]
Journal of Neuroimmunology 174(1-2): 39-51 (2006), 2007 In the present study, we show that ascorbic acid dose-dependently inhibited interleukin-1beta (IL-1beta)-mediated PGE2 synthesis in the human neuronal cell line, SK-N-SH. Furthermore, in combination with aspirin, ascorbic acid augmented the inhibitory effect of aspirin on PGE2 synthesis. However, ascorbic acid had no synergistic effect along with other
arxiv
Association of Hepatitis C Virus Infection and Interleukin-28B Gene Polymorphism in Chinese Children [PDF]
, 1969 Rongrong Wu +3 more
openalex +1 more source
Critical Care Medicine, 2016 Objective:To determine the efficacy of anakinra (recombinant interleukin-1 receptor antagonist) in improving 28-day survival in sepsis patients with features of macrophage activation syndrome.
B. Shakoory +7 more
semanticscholar +1 more source
Diverse Treatment Goals in Psoriatic Arthritis: Insights from participants in the PARC cohort
Arthritis Care &Research, Accepted Article.Objective The aim was to examine patient‐reported treatment goals among individuals with psoriatic arthritis (PsA). Methods Participants in the Psoriatic Arthritis Research Consortium (PARC) completed standardized assessments including patient‐reported outcome (PROs) instruments between 2017‐2020.
Astia Allenzara +8 more
wiley +1 more source
Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells. [PDF]
, 1986 Jordan S. Pober +5 more
openalex +1 more source