Results 11 to 20 of about 1,122,542 (370)

Effects of mesoporous SiO2-CaO nanospheres on the murine peritoneal macrophages -- Candida albicans interface [PDF]

Int Immunopharmacol International Immunopharmacology. 2021 Mar 20;94:107457, 2021
The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a central role in host defense and are responsible for in vivo nanoparticle trafficking.
arxiv   +1 more source

The Association of Gastritis and Peptic Ulcer With Polymorphisms in the Inflammatory-related Genes IL-4 and IL-10 in Iranian Population [PDF]

Iranian Journal of Pathology, 2018
Background and Objective: The current study aimed at assessing the relationship between gastritis and peptic ulcer susceptibility and inflammation-related gene polymorphisms in Iranian patients. Gastritis and peptic ulcer are common medical complications
Meysam Rezaeishahmirzadi, Neda Motamedi Rad, Mehdi Kalantar, Hossein Ayatollahi, Sepideh shakeri, Maryam Sheikhi, Mohammad Shekari   +6 more
doaj   +1 more source

Dietary 25-Hydroxyvitamin D3 Supplementation Modulates Intestinal Cytokines in Young Broiler Chickens

Frontiers in Veterinary Science, 2022
Vitamin D signaling is important for intestinal homeostasis. An increase in vitamin D receptors in immune cells can modulate cell phenotype and cytokine secretion.
Gerardo A. Abascal-Ponciano, Samuel F. Leiva, Joshua J. Flees, Luis P. Avila, Jessica D. Starkey, Charles W. Starkey   +5 more
doaj   +1 more source

Adropin and spexin hormones regulate the systemic inflammation in adenine-induced chronic kidney failure in rat

Chinese Journal of Physiology, 2021
Chronic kidney disease is one of the major global health problems. Chronic renal failure is stimulated by many cytokines and chemokines. Adropin and spexin (SPX) are peptides hormones.
Gulsun Memi, Burak Yazgan
doaj   +1 more source

Interleukin-7 and Interleukin-15 for Cancer [PDF]

Journal of Cancer, 2014
Interleukin 7 and 15 are considered powerful pro-inflammatory cytokines, they have the ability to destabilize chromosomes and induce tumorigenesis. Additionally, they can control malignancy proliferation by influencing the tumor microenvironment and immune system. Immunotherapy has been proposed as a treatment modality for malignancy for over a decade;
Zarogoulidis, P., Lampaki, S., Yarmus, L., Kioumis, I., Pitsiou, G., Katsikogiannis, N., Hohenforst-Schmidt, W., Li, Q., Huang, H., Sakkas, A., Organtzis, J., Sakkas, L., Mpoukovinas, I., Tsakiridis, K., Lazaridis, G., Syrigos, K., Zarogoulidis, K.   +16 more
openaire   +2 more sources

miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

Journal of Extracellular Vesicles, 2020
Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming, Brianna L. Hill, Mohammed W. Haque, Jessica Raad, Claudine S. Bonder, Larry A. Harshyne, Ulrich Rodeck, Adam Luginbuhl, James K. Wahl, Kenneth Y. Tsai, Peter J. Wermuth, Andrew M. Overmiller, Mỹ G. Mahoney   +12 more
doaj   +1 more source

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

Annals of the Rheumatic Diseases, 2012
Background Since approval of tocilizumab (TCZ) for treatment of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), interleukin 6 (IL-6) pathway inhibition was evaluated in trials of TCZ and other agents targeting the IL-6 receptor and ...
J. Smolen, M. Schoels, Norihiro Nishimoto, F. C. Breedveld, G. Burmester, M. Dougados, P. Emery, G. Ferraccioli, C. Gabay, A. Gibofsky, J. Gómez-Reino, Graeme Jones, T. Kvien, M. Murakami, N. Betteridge, Clifton O Bingham, V. Bykerk, Ernest Choy, B. Combe, Maurizio Cutolo, W. Graninger, Angel Lanas, Emilio Martín-Mola, C. Montecucco, Mikkel Ostergaard, K. Pavelka, A. Rubbert-Roth, Naveed Sattar, M. Scholte-Voshaar, Yoshiya Tanaka, Michael Trauner, Gabriele Valentini, Kevin L Winthrop, M. de Wit, D. M. van der Heijde   +34 more
semanticscholar   +1 more source

Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti-inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages [PDF]

Journal of HerbMed Pharmacology, 2022
Introduction: Antidesma thwaitesianum Müll. Arg is a tropical fruit, which has been commonly used for healthy food and traditional herbal medicine. This study aimed to investigate the anti-inflammatory effects of A. thwaitesianum fruit extract (AFE) rich
Orapin Insuan, Benchaluk Thongchuai, Supaporn Khamchun, Wimonrut Insuan, Daoyot Daorueang, Plubplung Sansai   +5 more
doaj   +1 more source

Molecular characterization and gene expression analysis of the pro-inflammatory cytokines IL-1β and IL-8 in the South American fish Piaractus mesopotamicus challenged with Aeromonas dhakensis [PDF]

Genetics and Molecular Biology, 2020
In the present study, the complete characterization of cDNA and genomic sequences of IL-1β and IL-8, as well as the expression profile of these genes in the South American fish pacu (Piaractus mesopotamicus) is provided.
Mateus Maldonado Carriero, Flavio Henrique-Silva, Caroline Munhoz Meira, Igor Mateus Queiroz Gato, Alexandre Rodrigues Caetano, Francisco Pereira Lobo, Anderson Luis Alves, Eduardo Sousa Varela, Antonio Augusto Mendes Maia   +8 more
doaj   +1 more source

Partial purification and functional characterization of Ts19 Frag-I, a novel toxin from Tityus serrulatus scorpion venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background The yellow scorpion Tityus serrulatus (Ts) is responsible for the highest number of accidents and the most severe scorpion envenoming in Brazil. Although its venom has been studied since the 1950s, it presents a number of orphan peptides that
Priscila C. Lima, Karla C. F. Bordon, Manuela B. Pucca, Felipe A. Cerni, Karina F. Zoccal, Lucia H. Faccioli, Eliane C. Arantes   +6 more
doaj   +1 more source