Journal of Leukocyte Biology, 2003 Abstract Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases.
Gracie, J.A. +2 more
openaire +6 more sources
Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti-inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages [PDF]
Journal of HerbMed Pharmacology, 2022 Introduction: Antidesma thwaitesianum Müll. Arg is a tropical fruit, which has been commonly used for healthy food and traditional herbal medicine. This study aimed to investigate the anti-inflammatory effects of A. thwaitesianum fruit extract (AFE) rich
Orapin Insuan +5 more
doaj +1 more source
Regulation of Type 2 Immunity in Myocardial Infarction
Frontiers in Immunology, 2019 Type 2 immunity participates in the pathogeneses of helminth infection and allergic diseases. Emerging evidence indicates that the components of type 2 immunity are also involved in maintaining metabolic hemostasis and facilitating the healing process ...
Jun-Yan Xu +3 more
doaj +1 more source
Interleukin-6 and tumor necrosis factor-α levels in tear film of Keratoconus patients
Journal of Research in Medical Sciences, 2021 Background: It is hypothesized that increased inflammatory markers in keratoconus (KC) may be one of the causes of corneal damage. The aim of our study was to the measurement of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL)-6 in tear of ...
Alireza Peyman +5 more
doaj +1 more source
Differences in Inflammatory Markers between Nulliparous Women Admitted to Hospitals in Preactive vs Active Labor [PDF]
, 2015 Objective To determine whether labor-associated inflammatory markers differ between low-risk, nulliparous women in preactive vs active labor at hospital admission and over time.
Arntzen +50 more
core +2 more sources
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]
, 2017 BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat +4 more
core +3 more sources
Interleukin-2 therapy in patients with HIV infection [PDF]
, 2009 BACKGROUND Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone. The clinical implication of these increases is not known.
Aagaard, B. +49 more
core +5 more sources
Paraneoplastic thrombocytosis in ovarian cancer [PDF]
, 2012 <p>Background: The mechanisms of paraneoplastic thrombocytosis in ovarian cancer and the role that platelets play in abetting cancer growth are unclear.</p> <p>Methods: We analyzed clinical data on 619 patients with epithelial ...
Akl EA +35 more
core +1 more source
Anti-inflammatory effects of shikonin in human periodontal ligament cells
Pharmaceutical Biology, 2018 Context: Shikonin (SHI), an active component extracted from Radix Arnebiae, has been reported to possess anti-inflammatory properties in various cells.
Chen Fan, Xufang Zhang, Zee Upton
doaj +1 more source
Interleukin-1 polymorphisms associated with increased risk of gastric cancer [PDF]
, 2000 Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and ...
A Cox +42 more
core +2 more sources