Results 21 to 30 of about 1,122,542 (370)
Insight into the Possible Association between Gene Polymorphism of IFN-γ and IL-22 with Psoriasis in Punjab, India [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: IFN-γ and IL-22 are Th1/Th17 cytokine which have been shown to play important role in the development of autoimmune disorder like psoriasis. Aim: To identify the possible association of IFN-γ and IL-22 Single Nucleotide Polymorphisms (SNPs)
Arun Kumar Rawat +7 more
doaj +1 more source
Journal of Nature and Science of Medicine, 2023 Objective: The aim of this study is to reveal the relationship between the cytokine plasma levels and symptoms of coronavirus disease-2019 (COVID-19)-positive patients, which is characterized by serious respiratory syndromes.
H Seda Vatansever +5 more
doaj +1 more source
The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond
Frontiers in Immunology, 2018 Psoriasis is a frequent chronic inflammatory skin disease, nowadays considered a major global health problem. Several new drugs, targeting the IL-23/IL-17A pathway, have been recently licensed or are in clinical development.
Nicolo Costantino Brembilla +3 more
doaj +1 more source
Emerging Roles of Dysregulated MicroRNAs in Myasthenia Gravis
Frontiers in Neuroscience, 2020 Myasthenia gravis (MG) is a rare acquired autoimmune neuromuscular disease. Autoantibodies, cellular immunity, complement, and cytokines are involved in the pathogenesis of MG. It is characterized by the dysfunction of neuromuscular junction transmission
Lin Wang, Lijuan Zhang
doaj +1 more source
The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets
Frontiers in Medicine, 2023 Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also referred to as BP180, is the main pathogenic event of BP, leading to production
Roberto Maglie +6 more
doaj +1 more source
Analysis of Lymphocyte Subsets Including Th17 Cells in Alcoholic Liver Disease [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Alcoholic Liver Disease (ALD), which consists of three major diseases: (1) fatty liver, (2) alcoholic hepatitis and (3) cirrhosis, is described to be associated with lymphopenia and an altered ratio of lymphocyte subsets but the reported
BIDYUT BIKASH GOGOI +5 more
doaj +1 more source
Biologic basis for interleukin-1 in disease.
Blood, 1996 To understand the role of the proinflammatory cytokine interleukin-1 (IL-1) in disease, investigators have studied how production of the different members of the IL-1 family is controlled, the various biologic activities of IL-1, the distinct and various
C. Dinarello
semanticscholar +1 more source
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
Circulation Research, 2020 Supplemental Digital Content is available in the text. The intracellular sensing protein termed NLRP3 (for NACHT, LRR, and PYD domains-containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome.
A. Abbate +5 more
semanticscholar +1 more source
Relationship between TIM3 Expression on Peripheral T Lymphocytes and Post-Stroke Depression [PDF]
Iranian Journal of Immunology, 2023 Background: T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) is a regulatory molecule expressed on a variety of cell types, including CD3+ T cells.
Qifen Mao +8 more
doaj +1 more source
Principles of interleukin (IL)-6-type cytokine signalling and its regulation.
Biochemical Journal, 2003 The IL (interleukin)-6-type cytokines IL-6, IL-11, LIF (leukaemia inhibitory factor), OSM (oncostatin M), ciliary neurotrophic factor, cardiotrophin-1 and cardiotrophin-like cytokine are an important family of mediators involved in the regulation of the ...
P. Heinrich +5 more
semanticscholar +1 more source