Results 41 to 50 of about 1,122,542 (370)

Evaluation of inflammatory response in patients undergoing surgical treatment for early and delayed femoral fractures

open access: yesArchives of Medical Science, 2018
Introduction It has been shown that long bone fractures are correlated with the inflammatory response. In the initial injury, surgical reduction and fixation of fractures induce the immunoinflammatory response.
Mehdi Moghtadaei   +4 more
doaj   +1 more source

Ten interleukins and risk of prostate cancer

open access: yesFrontiers in Oncology, 2023
BackgroundInterleukins (ILs) have been reported to be related to prostate cancer. The aims of this study were to estimate the levels for several key interleukins in prostate cancer and the causal effects between them.MethodsWe conducted a bi-directional ...
Bing-Hui Li   +8 more
doaj   +1 more source

A Fast Second-Order Explicit Predictor-Corrector Numerical Technique To Investigating And Predicting The Dynamic Of Cytokine Levels And Human Immune Cells Activation In Response To Gram-Positive Bacteria: Staphylococcus Aureus [PDF]

open access: yesarXiv, 2023
This paper develops a second-order explicit predictor-corrector numerical approach for solving a mathematical model on the dynamic of cytokine expressions and human immune cell activation in response to the bacterium staphylococcus aureus (S. aureus). The proposed algorithm is at least zero-stable and second-order accurate.
arxiv  

Marine n-3 Polyunsaturated Fatty Acids and Cellular Senescence Markers in Incident Kidney Transplant Recipients: The Omega-3 Fatty Acids in Renal Transplantation (ORENTRA) Randomized Clinical TrialPlain-Language Summary

open access: yesKidney Medicine, 2021
Rationale & Objective: Deterioration of kidney graft function is associated with accelerated cellular senescence. Marine n-3 polyunsaturated fatty acids (PUFAs) have favorable properties that may counteract cellular senescence development and damage ...
Joe Chan   +5 more
doaj  

Immune checkpoint inhibitor therapy increases systemic SDF-1, cardiac DAMPs Fibronectin-EDA, S100/Calgranulin, galectine-3, and NLRP3-MyD88-chemokine pathways

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundImmune checkpoint inhibitors (ICIs) have significantly changed the oncology clinic in recent years, improving survival expectations in cancer patients.
Vincenzo Quagliariello   +16 more
doaj   +1 more source

Interleukin-17A and interleukin-23 in morphea

open access: yesArchives of Medical Science, 2012
Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea.The studies were performed on 41 ...
Anna Olewicz-Gawlik   +9 more
openaire   +3 more sources

Interleukin-1 and Interleukin-6 in Psoriasis

open access: yesJournal of Investigative Dermatology, 1990
We report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, using a sensitive enzyme-linked immunoabsorbent assay (ELISA) and bio-assay.
Jozef Van Damme   +6 more
openaire   +3 more sources

Age-dependent immune responses in COVID-19-mediated liver injury: focus on cytokines

open access: yesFrontiers in Endocrinology, 2023
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is potentially pathogenic and causes severe symptoms; in addition to respiratory syndromes, patients might experience other severe conditions such as digestive complications and liver ...
Nazanin Aghamohamadi   +7 more
doaj   +1 more source

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

open access: yesCell Research, 2015
Inflammasome is an intracellular signaling complex of the innate immune system. Activation of inflammasomes promotes the secretion of interleukin 1β (IL-1β) and IL-18 and triggers pyroptosis.
Wan-ting He   +8 more
semanticscholar   +1 more source

How native state topology affects the folding of Dihydrofolate Reductase and Interleukin-1beta [PDF]

open access: yes, 2000
The overall structure of the transition state and intermediate ensembles experimentally observed for Dihydrofolate Reductase and Interleukin-1beta can be obtained utilizing simplified models which have almost no energetic frustration. The predictive power of these models suggest that, even for these very large proteins with completely different folding
arxiv   +1 more source

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