Interleukin-1 and Interleukin-6 in Psoriasis
We report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, using a sensitive enzyme-linked immunoabsorbent assay (ELISA) and bio-assay.
Jozef Van Damme +6 more
openaire +3 more sources
IMMUNOMODULATORY EFFECT OF CURCUMA LONGA IN MICE [PDF]
This study was designed to find out the effect of oral inoculation of aqueous extract of Curcuma Longa at two doses (1 and 5) mg/ kg body weight daily for 4 weeks on the immune response of Balb/c mice by estimating of serum concentration of interleukin-2
Abeer L. Mohammed
doaj +1 more source
Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling [PDF]
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Alessio +15 more
core +2 more sources
Interleukin-18: Perspectives on the Newest Interleukin
Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been ...
Gillespie, M T, Horwood, N J
openaire +4 more sources
Background and Objectives: The elicitation of a host’s immune–inflammatory responses to overcome oral bacterial biofilm challenges is mediated by numerous cytokines. We explored the role of three such cytokines, viz.
Vineet Nair +8 more
doaj +1 more source
Interleukin-1 and interleukin-1 antagonism [PDF]
The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
openaire +4 more sources
Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Craen, A.J.M. de +11 more
core +1 more source
The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA ...
Heidi Braumüller +5 more
doaj +1 more source
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. [PDF]
BACKGROUND: To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 (IL-1) inhibition, we studied genetic variants that produce inhibition of IL-1, a master regulator of inflammation.
Interleukin 1 Genetics Consortium
core
Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
A Kitamura +99 more
core +3 more sources

