Results 51 to 60 of about 1,122,542 (370)

Interleukin-18: Perspectives on the Newest Interleukin

open access: yesCytokine & Growth Factor Reviews, 1998
Just over two years ago the newest member of the interleukin family of cytokines, IL-18, was molecularly cloned. IL-18 was originally identified as a result of its ability to induce interferon gamma production, however with the advent of its cloning and the production of recombinant protein a number of other biological actions have since been ...
Gillespie, M T, Horwood, N J
openaire   +4 more sources

Interleukin-1 and interleukin-1 antagonism [PDF]

open access: yesBlood, 1991
The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a variety of genes and the synthesis of several proteins that, in turn, induce acute and chronic inflammatory changes.
openaire   +4 more sources

Regulation of Mouse Learning and Mood by the Anti-Inflammatory Cytokine Interleukin-10 [PDF]

open access: yes2020. Doctoral dissertation, University of Miami Miller School of Medicine. University of Miami Research Repository. https://scholarship.miami.edu/esploro/outputs/991031524489402976 ISBN: 9798698577058, 2023
Major depressive disorder is a widespread mood disorder. One of the most debilitating symptoms patients often experience is cognitive impairment. Recent findings suggest that inflammation is associated with depression and impaired cognition. Pro-inflammatory cytokines are elevated in the blood of depressed patients and impair learning and memory ...
arxiv  

Interleukin-18 in Health and Disease

open access: yesInternational Journal of Molecular Sciences, 2019
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12.
K. Yasuda, K. Nakanishi, H. Tsutsui
semanticscholar   +1 more source

Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

open access: yesPharmaceuticals, 2022
Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation of ...
Ajjampura C. Vinayaka   +8 more
doaj   +1 more source

The role of interleukin-1 in general pathology

open access: yesInflammation and Regeneration, 2019
Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological functions and pathological significances and play an important role in health and disease.
Naoe Kaneko   +4 more
semanticscholar   +1 more source

Induction in myeloid leukemic cells of genes that are expressed in different normal tissues [PDF]

open access: yesPNAS 101, 16022 (2004), 2005
Using DNA microarray and cluster analysis of expressed genes in a cloned line (M1-t-p53) of myeloid leukemic cells, we have analyzed the expression of genes that are preferentially expressed in different normal tissues. Clustering of 547 highly expressed genes in these leukemic cells showed 38 genes preferentially expressed in normal hematopoietic ...
arxiv   +1 more source

Comparative Evaluation of Gingival Crevicular Fluid Interleukin-17, 18 and 21 in Different Stages of Periodontal Health and Disease

open access: yesMedicina, 2022
Background and Objectives: The elicitation of a host’s immune–inflammatory responses to overcome oral bacterial biofilm challenges is mediated by numerous cytokines. We explored the role of three such cytokines, viz.
Vineet Nair   +8 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Evaluating the Use of Generalized Dynamic Weighted Ordinary Least Squares for Individualized HIV Treatment Strategies [PDF]

open access: yesarXiv, 2021
Dynamic treatment regimes (DTR) are a statistical paradigm in precision medicine which aim to optimize patient outcomes by individualizing treatments. At its simplest, a DTR may require only a single decision to be made; this special case is called an individualized treatment rule (ITR) and is often used to maximize short-term rewards.
arxiv  

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