Results 51 to 60 of about 1,262,607 (212)

Interleukin 10 gene polymorphisms and frailty syndrome in elderly Mexican people: (Sadem study)

Molecular Genetics & Genomic Medicine, 2019
Frailty is a geriatric syndrome, characterized by a loss in functional reserve with an increase in morbidity and mortality. There are no reports that link the genetic polymorphisms between interleukin 10 (IL10) and frailty; for this reason, our objective
Teresa Juárez‐Cedillo, Gilberto Vargas‐Alarcón, Nancy Martínez‐Rodríguez, Enrique Juárez‐Cedillo, José Manuel Fragoso, Jorge Escobedo‐de‐la‐Peña   +5 more
doaj   +1 more source

Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. [PDF]

, 2015
BACKGROUND: To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 (IL-1) inhibition, we studied genetic variants that produce inhibition of IL-1, a master regulator of inflammation.
Interleukin 1 Genetics Consortium
core  

Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]

, 2017
BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat, Jobe, Alan H, Kallapur, Suhas G, Kannan, Paranthaman Senthamarai, Kemp, Matthew W   +4 more
core   +3 more sources

The relationship between coronavirus disease-2019-positive patients and plasma interleukins and transforming growth factor-β levels

Journal of Nature and Science of Medicine, 2023
Objective: The aim of this study is to reveal the relationship between the cytokine plasma levels and symptoms of coronavirus disease-2019 (COVID-19)-positive patients, which is characterized by serious respiratory syndromes.
H Seda Vatansever, Murat Sayan, Melike Ozgul-Onal, Sila Akhan, Selcan Ozel, Tamer Sanlidag   +5 more
doaj   +1 more source

Signaling via interleukin-4, receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice [PDF]

, 2001
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson S., Anderson S., Anderson S., Artis D., Bancroft A. J., Bancroft A. J., Barner M., Belkaid Y., Brewer J. M., Brombacher F., Coulson P. S., D'Andrea A., de Andres B., Dean D. A., Delgado V., Donaldson D. D., Faquim-Mauro E. L., Galbiati F., Grunig G., Guler M. L., Hilton D. J., Hoffmann K. F., Hsieh C. S., James S. L., Jankovic D., Jankovic D., Jankovic D., King C. L., King C. L., Kopf M., Magram J., Mangold B. L., Matthews D. J., Mattner F., McKenzie G. J., Metwali A., Mohrs M., Mohrs M., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Mountford A. P., Muchamuel T., Nelms K., Noben-Trauth N., Noben-Trauth N., Noben-Trauth N., O'Garra A., Pearce E. J., Reiner S. L., Scott P., Seder R. A., Sher A., Shibuya K., Smythies L. E., Smythies L. E., Street M., Szabo S. J., Urban J. F., Wilson R. A., Wynn T. A., Wynn T. A., Zurawski G.   +64 more
core   +2 more sources

Interleukin (IL)-1B and IL-1 receptor antagonist gene polymorphisms in children with primary immune thrombocytopenia [PDF]

Clinical and Experimental Pediatrics
Background The pathophysiology and susceptibility of children to primary immune thrombocytopenia (ITP) are linked to polymorphisms of the interleukin (IL)-1B and IL-1 receptor (IL-1R) antagonist genes.
Seham Mohamed Ragab, Wafaa Moustafa Abo ElFotoh, Mahmoud Ahmed El-Hawy, Eman Abdelfatah Badr, Saara Khairat Ali Mostafa, Mai El-Sayad Abd El-Hamid   +5 more
doaj   +1 more source

Comparative Evaluation of Gingival Crevicular Fluid Interleukin-17, 18 and 21 in Different Stages of Periodontal Health and Disease

Medicina, 2022
Background and Objectives: The elicitation of a host’s immune–inflammatory responses to overcome oral bacterial biofilm challenges is mediated by numerous cytokines. We explored the role of three such cytokines, viz.
Vineet Nair, Vishakha Grover, Suraj Arora, Gotam Das, Irfan Ahmad, Anchal Ohri, Shan Sainudeen, Priyanka Saluja, Arindam Saha   +8 more
doaj   +1 more source

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]

, 2009
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon, Barranco, Wade T, Corry, David B, Dong, Chen, Goswami, Sangeeta, Greenlee, Kendra J, Kheradmand, Farrah, Polikepahad, Sumanth, Redding, David, Seryshev, Alexander, Shan, Ming, Singh, Bhupinder, Song, Li-zhen, Sur, Sanjiv, Woodruff, Prescott   +14 more
core  

The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies

Cells, 2022
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA ...
Heidi Braumüller, Bernhard Mauerer, Johanna Andris, Christopher Berlin, Thomas Wieder, Rebecca Kesselring   +5 more
doaj   +1 more source

Interleukin-6 and tumor necrosis factor-α levels in tear film of Keratoconus patients

Journal of Research in Medical Sciences, 2021
Background: It is hypothesized that increased inflammatory markers in keratoconus (KC) may be one of the causes of corneal damage. The aim of our study was to the measurement of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL)-6 in tear of ...
Alireza Peyman, Mohammad Namgar, Awat Feizi, Mazdak Ganjalikhani Hakemi, Fahimeh Hosseini Nasab, Mohsen Pourazizi   +5 more
doaj   +1 more source