Results 81 to 90 of about 1,122,542 (370)
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Cells, 2021 Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 and IL-33) and Th17 (IL-17, IL-17F, IL-21, IL-22, IL-23 and TGF-
Anna Waśkiel-Burnat +6 more
doaj +1 more source
Biology and therapeutic potential of interleukin-10
Journal of Experimental Medicine, 2019 The authors review the molecular mechanisms regulating IL-10 production and response and describe classic and novel functions of IL-10 in immune and non-immune cells.
M. Saraiva, P. Vieira, A. O’Garra
semanticscholar +1 more source
Role of Interleukin-6 in Depressive Disorder
International Journal of Molecular Sciences, 2020 Major depressive disorder (MDD), which is a leading psychiatric illness across the world, severely affects quality of life and causes an increased incidence of suicide.
Emily Yi-Chih Ting, A. Yang, S. Tsai
semanticscholar +1 more source
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine IL-6 are related to synovitis and pain in end-stage knee osteoarthritis patients [PDF]
Pain. 2017 Jul;158(7):1254-1263, 2019 Little is known about local and systemic biomarkers in relation to synovitis and pain in end-stage osteoarthritis (OA) patients. We investigated the associations between the novel extracellular matrix biomarker, C1M, and local and systemic interleukin 6 (IL-6) with synovitis and pain.
arxiv +1 more source
Investigating Histological Changes and Gene Expression of Interleukin-8, Interleukin-12, and Interferon Beta in Liver Tissue After Consumption of Lactobacillus rhamnosus GG Probiotic in Steatosis Model Rats [PDF]
Armaghane Danesh Bimonthly Journal, 2022 Background & aim: Probiotic consumption can regulate the homeostasis of the digestive system and control metabolic diseases related to the digestive system. Therefore, the purpose of the present study was to determine and investigate histological changes
F Rostamkhani
doaj
The Interleukins Orchestrate Mucosal Immune Responses to Salmonella Infection in the Intestine
Cells, 2021 Salmonella infection remains one of the major public health problems in the world, with increasing resistance to antibiotics. The resolution is to explore the pathogenesis of the infection and search for alternative therapy other than antibiotics. Immune
Fu-Chen Huang
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
eLife, 2017 The cutaneous wound-healing program is a product of a complex interplay among diverse cell types within the skin. One fundamental process that is mediated by these reciprocal interactions is the mobilization of local stem cell pools to promote tissue ...
Pedro Lee +11 more
doaj +1 more source