Results 111 to 120 of about 1,132,369 (355)

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)

Molecular Therapy: Nucleic Acids, 2013
The cytokine interleukin 1(IL-1) initiates a wide range of proinflammatory cascades and its inhibition has been shown to decrease inflammation in a variety of diseases.
A Seda Yılmaz-Eliş, Annemieke Aartsma-Rus, Peter AC 't Hoen, Huma Safdar, Cor Breukel, Bart JM van Vlijmen, Judith van Deutekom, Sjef de Kimpe, Gert-Jan van Ommen, J Sjef Verbeek   +9 more
doaj   +1 more source

Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. [PDF]

, 2018
BackgroundObesity is associated with gut microbiota dysbiosis, disrupted intestinal barrier and chronic inflammation. Given the high and increasing prevalence of obesity worldwide, anti-obesity treatments that are safe, effective and widely available ...
Chang, C-J, Ko, Y-F, Lai, H-C, Lin, C-S, Lu, C-C, Lu, J-J, Martel, J, Ojcius, DM, Tsai, Y-H, Wu, T-R, Yeh, T-S, Young, JD   +11 more
core  

Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3 [PDF]

, 2017
Jiazhen Zhang, Thomas Macartney, Mark Peggie, Philip Cohen   +3 more
openalex   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Successful treatment of periodic disease and secondary AA amyloidosis in a colchicine-resistant patient

Alʹmanah Kliničeskoj Mediciny, 2018
The paper demonstrates current opportunities of effective management of periodic disease as an autoinflammatory disorder based on a clinical case of colchicine-resistant Mediterranean fever. We present modern approaches to the autoinflammation hypothesis
V. V. Rameev, M. V. Bogdanova, L. V. Kozlovskaya, N. A. Mukhin   +3 more
doaj   +1 more source

Inhaled Interleukin-10 before and after induction of experimental endotoxemia in the rat : effects on the inflammatory response [PDF]

, 2007
To determine the effects of inhaled IL-10 at different doses and different time points on the pulmonary and systemic inflammatory response during endotoxemia, 48 ventilated, anaesthetized rats (mean body weight ± standard deviation, 500 ± 33g) were ...
Nguyen, Ngoc-Thach
core  

Human intraovarian interleukin-1 (IL-1) system: highly compartmentalized and hormonally dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist. [PDF]

, 1992
Arye Hurwitz, Jill A. Loukides, E. Ricciarelli, Luis Botero, E. Katz, J M McAllister, José E. García, Richard M. Rohan, Eli Y. Adashi, Eleuterio R. Hernández   +9 more
openalex   +1 more source

Associations of lifestyle‐related factors and psoriatic arthritis disease activity: the Dutch south west psoriatic arthritis study

Arthritis Care &Research, Accepted Article.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients newly diagnosed with PsA, between 2013 and 2023. A composite lifestyle risk score (range 0 to 5) was calculated using five lifestyle‐
Batoul Hojeij, Ilja Tchetverikov, Marc R. Kok, Marijn Vis, Yvonne Goekoop‐Ruiterman, Jessica Bijsterbosch, Paul Baudoin, Reinhard Bos, Jos H. van der Kaap, Petra Kok, Lindy‐Anne Korswagen, Jolanda J. Luime   +11 more
wiley   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist [PDF]

Proceedings of the Nutrition Society, 1994
N. Joseph Espat, Michael A. Rogy, Edward M. Copeland, Lyle L. Moldawer   +3 more
openaire   +1 more source