Tzu Chi Medical Journal, 2020 Objective: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular ...
Chun-Chun Chang +5 more
doaj +4 more sources
Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. [PDF]
, 1996 The mechanism by which the mammalian mother accepts the implanting fetus as an allograft remains unexplained, but is likely to be the result of a combination of factors.
Irene Roth +5 more
openalex +4 more sources
Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population
Mutiara Medika, 2021 Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
doaj +1 more source
The perspectives of interleukin-10 in the pathogenesis and therapeutics of multiple myeloma
Tzu Chi Medical Journal, 2021 Multiple myeloma (MM) is typically featured by the increased levels of inflammatory cytokines in the neoplastic plasma cells (PCs) producing monoclonal immunoglobulin.
Cheng-Der Liu +2 more
doaj +1 more source
Journal of Inflammation, 2021 Background The differences between adults and children in inflammatory bowel disease (IBD) phenotype, severity, complications, co-morbidities, and response to the therapy resulted in the extraction of paediatric IBD.
Paulina Krawiec +2 more
doaj +1 more source
Serum levels of interleukin-10 and its receptor in the multiple myeloma type I patients [PDF]
Journal of Research in Applied and Basic Medical Sciences, 2023 Background & Aims: Multiple myeloma is a malignancy of plasma cells that is associated with high morbidity rate. Inflammation is a common feature in malignancy and plays a pivotal role in the cancer pathogenesis.
Mehdi Rajabzadeh +4 more
doaj
Role of interleukin 1β and interleukin 10 variants on ocular toxoplasmosis in Brazilian individuals
Frontiers in Ophthalmology, 2023 IntroductionOcular toxoplasmosis (OT) is an intraocular inflammation caused by Toxoplasma gondii infection that affects the retina and choroid, giving rise to posterior uveitis.
Warlen Miiller Rocha Araujo +12 more
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IDENTIFICATION OF -2849 IL-10 GENE PROMOTER POLYMORPHISM IN LEPROSY PATIENT
Jurnal Kedokteran dan Kesehatan, 2022 Leprosy is a chronic granulomatous disease. Leprosy is caused by M. leprae. However, not all exposure to M. leprae causes the disease. The condition of the host immune system determines the pathogenesis of leprosy.
Desi Oktariana +2 more
doaj +1 more source
Association of interleukin 10 rs1800896 polymorphism with susceptibility to breast cancer: a meta-analysis. [PDF]
, 2020 Objective: To evaluate the correlation between interleukin 10 (IL-10) -1082A/G polymorphism (rs1800896) and breast cancers by performing a meta-analysis.
Liu, Ji-Bin +3 more
core +2 more sources
Differences in Inflammatory Markers between Nulliparous Women Admitted to Hospitals in Preactive vs Active Labor [PDF]
, 2015 Objective To determine whether labor-associated inflammatory markers differ between low-risk, nulliparous women in preactive vs active labor at hospital admission and over time.
Arntzen +50 more
core +2 more sources