Results 241 to 250 of about 80,902,661 (299)

Integrated transcriptomic and proteomic profiling of colonic tissue in interleukin-10-deficient mice. [PDF]

Sci Data
Li L, Ma C, Chen K, Jia Y, Wu Y, Lin H, Cheng R, Jiang M, Zeng Z, Chen J, Pang J, Li J, Zhang H.   +12 more
europepmc   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Myeloid-derived interleukin-10 induced by thrombospondin-1 mediates host defense and regulates inflammation during acute bacterial lung infection. [PDF]

Infect Immun
Jara-Collao A, Román F, Torres-Ayala G, Novoa F, Moreno-Quidecoy C, Jara A, González PA, Bueno SM, Kalergis AM, Peñaloza HF.   +9 more
europepmc   +1 more source

Interleukin-10 expressing B lineage cells in visceral adipose tissue protect against aging-related insulin resistance and extend lifespan. [PDF]

Nat Commun
Guo J, Han X, Qin Y, Hong K, Lin Y, Han S, Hou N, Cao L, Gao X, Huang W, Liu X, Zhan J, You Y.   +12 more
europepmc   +1 more source

Diagnostic Performance of CSF Interleukin-10 in Primary Central Nervous System Lymphoma: A Retrospective Study. [PDF]

Cureus
Villanueva-Castro E, Flores-Vázquez JG, Hernández Reséndiz R, Rodríguez-Hernández LA, Rodríguez-Hernández IA, Villalobos-Díaz R, Moncada-Habib T, Muñuzuri-Camacho MA, Mateo-Nouel EJ, Wong-Achi X, Palacios-Rodríguez RA, Cacho-Díaz B, Gutierrez-Aceves GA, Moreno-Jiménez S, González-Aguilar A.   +14 more
europepmc   +1 more source

Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling. [PDF]

Nat Commun
Schmidt-Pogoda A, Ruck T, Strecker JK, Hoppen M, Fazio L, Vinnenberg L, Maus B, Wachsmuth L, Cerina M, Diederich K, Lichtenberg S, Abberger H, Haertel L, Schafflick D, Meyer Zu Hörste G, Herrmann AM, Hundehege P, Narayanan V, Nelke C, Kruithoff K, Bosbach J, Vicari E, Ramcke T, Beuker C, Hadaschik E, Budde T, Faber C, Wiendl H, Hansen W, Meuth SG, Minnerup J.   +30 more
europepmc   +1 more source

RETRACTION: Interleukin-10-Modified Adipose-Derived Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Regulating the Biological Characteristics of Fibroblasts and Inflammation. [PDF]

Mediators Inflamm
Inflammation MO.
europepmc   +1 more source

Interleukin-10 augments human endogenous retroviral E1B variant of cd5 in aged T cells. [PDF]

Blood Res
Singh B, Kumari S, Kureel AK, Shah A, Katiyar S, Chaturvedi CP, Singh K, Rai AK.   +7 more
europepmc   +1 more source

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Interleukin-10

Current Opinion in Immunology, 1992
Despite the short history of interleukin-10, accumulated evidence indicates that this interleukin plays a major role in suppressing immune and inflammatory responses. Yet interleukin-10 also maintains cell viability and acts as a cofactor to promote the growth of lymphoid and myeloid cells in vitro. Here we review the present knowledge on the structure
R, de Waal Malefyt, H, Yssel, M G, Roncarolo, H, Spits, J E, de Vries   +4 more
  +7 more sources

Interleukin-10

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2006
Interleukin (IL)-10, initially described as cytokine synthesis inhibitory factor, is a pleotropic cytokine produced by many cell populations. Its main biological functions appear to be quite diverse: on the one hand it is involved in the limitation and termination of inflammatory responses and the regulation of differentiation and proliferation of ...
K. Asadullah, R. Sabat, M. Friedrich, W. D. Docke, H. D. Volk, W. Sterry   +5 more
  +5 more sources