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Impacts of Interleukin-10 Promoter Genotypes on Prostate Cancer. [PDF]

open access: yesLife (Basel)
Chin YT   +10 more
europepmc   +1 more source

Upregulation of delta opioid receptor by meningeal interleukin-10 prevents relapsing pain. [PDF]

open access: yesBrain Behav Immun
Inyang KE   +18 more
europepmc   +1 more source
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Interleukin-10

Current Opinion in Immunology, 1992
Despite the short history of interleukin-10, accumulated evidence indicates that this interleukin plays a major role in suppressing immune and inflammatory responses. Yet interleukin-10 also maintains cell viability and acts as a cofactor to promote the growth of lymphoid and myeloid cells in vitro. Here we review the present knowledge on the structure
R, de Waal Malefyt   +4 more
  +7 more sources

Interleukin-10

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2006
Interleukin (IL)-10, initially described as cytokine synthesis inhibitory factor, is a pleotropic cytokine produced by many cell populations. Its main biological functions appear to be quite diverse: on the one hand it is involved in the limitation and termination of inflammatory responses and the regulation of differentiation and proliferation of ...
K. Asadullah   +5 more
  +5 more sources

Interleukin-10

Annual Review of Immunology, 1993
In the three years since its discovery, the pleiotropic cytokine interleukin-10 (IL-10) has been implicated as an important regulator of the functions of lymphoid and myeloid cells. IL-10's ability to block activation of cytokine synthesis and several accessory cell functions of macrophage renders this cytokine a potent suppressor of the effector ...
K W, Moore   +4 more
openaire   +3 more sources

Interleukin-10

BioDrugs, 1997
Interleukin-10 (IL-10) is a potent anti-inflammatory and immunosuppressive cytokine secreted by several cell types. Most anti-inflammatory effects of IL-10 are caused by its ability to deactivate macrophages and monocytes, whereas its immunosuppressive properties are due to functional inhibition of both antigen-presenting cells and T cells.
Goldman, Michel   +2 more
openaire   +3 more sources

Interleukin-10 and the Interleukin-10 Receptor

Annual Review of Immunology, 2001
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types. The principal routine function of IL-10 appears to be to limit and ultimately terminate inflammatory responses.
K W, Moore   +3 more
openaire   +2 more sources

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