Results 221 to 230 of about 4,886,092 (271)
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Measurement of Human Interleukin 11
Current Protocols in Immunology, 1996AbstractThis unit describes an ELISA and a cell proliferation assay that can be used, respectively, to measure the protein level or biologic activity of human and murine interleukin 11 (IL‐11). The bioassay is based on the ability of IL‐11 to support growth of the B9‐11 cell line, a subline of B9 that has traditionally been used to measure levels of IL‐
Frann, Bennett +4 more
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STEM CELLS, 1993
Interleukin (IL)-11 is a bone marrow fibroblast derived cytokine with a wide spectrum of in vitro biological activities in the hematopoietic, lymphopoietic, hepatic, adipose, neuronal and osteoclast systems, either alone or in synergy with other hematopoietic growth factors.
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Interleukin (IL)-11 is a bone marrow fibroblast derived cytokine with a wide spectrum of in vitro biological activities in the hematopoietic, lymphopoietic, hepatic, adipose, neuronal and osteoclast systems, either alone or in synergy with other hematopoietic growth factors.
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Update on development of interleukin-11
Current Opinion in Hematology, 1995This paper reviews the recent studies of interleukin-11 gene expression and regulation, receptor and signal transduction, pharmacologic effects, and preclinical and clinical studies. Interleukin-11 is expressed in cells of mesenchymal origin and gene expression can be modulated by several inflammatory cytokines and agonists.
X, Du, D A, Williams
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Interleukin-6 and interleukin-11: same same but different
bchm, 2013Abstract The pleiotropic physiological functions of interleukin (IL-)6 type cytokines range from embryonic development and tissue homoeostasis to neuronal development and T cell differentiation. In contrast, imbalance of the well-controlled cytokine signaling network leads to chronic inflammatory diseases and cancer.
Christoph, Garbers, Jürgen, Scheller
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Interleukin-11 inhibits macrophage interleukin-12 production
The Journal of Immunology, 1997Abstract IL-12 is a heterodimeric cytokine produced by phagocytic and other cells with important physiologic and pathologic properties. Regulated IL-12 production is crucial for the generation of protective Th1 responses to infectious agents.
S X, Leng, J A, Elias
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Experimental Cell Research, 2018
Cancer‐associated fibroblasts (CAFs) are major components of the tumor stroma and regulators of tumor progression. However, the molecular mechanism by which CAFs promote gastric cancer progression should be further explored.
Xiaoxun Wang +11 more
semanticscholar +1 more source
Cancer‐associated fibroblasts (CAFs) are major components of the tumor stroma and regulators of tumor progression. However, the molecular mechanism by which CAFs promote gastric cancer progression should be further explored.
Xiaoxun Wang +11 more
semanticscholar +1 more source
Science Signaling, 2018
Autocrine responses to interleukin-6 family cytokines are insensitive to extracellular gp130 signaling receptor blockade. Inside IL-6 inflammation Members of the interleukin-6 (IL-6) family of proinflammatory cytokines, which includes IL-6 and IL-11 ...
Larissa Lamertz +8 more
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Autocrine responses to interleukin-6 family cytokines are insensitive to extracellular gp130 signaling receptor blockade. Inside IL-6 inflammation Members of the interleukin-6 (IL-6) family of proinflammatory cytokines, which includes IL-6 and IL-11 ...
Larissa Lamertz +8 more
semanticscholar +1 more source
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2012
Interleukin-11 (IL-11) is a cytokine which interacts with a variety of haemopoietic and non-haemopoietic cell types. Recombinant human IL-11 (rhIL-11; oprelvekin) is produced in Escherichia coli and differs from the naturally occurring protein only in the absence of the amino-terminal proline residue.
A J, Dorner, S J, Goldman, J C, Keith
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Interleukin-11 (IL-11) is a cytokine which interacts with a variety of haemopoietic and non-haemopoietic cell types. Recombinant human IL-11 (rhIL-11; oprelvekin) is produced in Escherichia coli and differs from the naturally occurring protein only in the absence of the amino-terminal proline residue.
A J, Dorner, S J, Goldman, J C, Keith
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Journal of Clinical Periodontology, 2008
AbstractObjectives: The balance between pro‐inflammatory and anti‐inflammatory cytokines may be crucial for determining the immunopathology of gingivitis (G) and periodontitis. This study aimed to analyse interleukin‐1β (IL‐1β), IL‐11 and IL‐12 levels in gingival crevicular fluid (GCF) of patients with G and chronic periodontitis (CP).Material and ...
Ozlem Ozer, Yücel +3 more
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AbstractObjectives: The balance between pro‐inflammatory and anti‐inflammatory cytokines may be crucial for determining the immunopathology of gingivitis (G) and periodontitis. This study aimed to analyse interleukin‐1β (IL‐1β), IL‐11 and IL‐12 levels in gingival crevicular fluid (GCF) of patients with G and chronic periodontitis (CP).Material and ...
Ozlem Ozer, Yücel +3 more
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1995
Abstract The nucleotide sequences of IL-11 cDNAs cloned from mouse and man (mouse sequence submitted to GenBank, human sequence GenBank accession number M37006) encode proteins with 199 amino acids (Fig. 1) (Paul eta/. 1990). At the amino acid level, the mouse and human proteins are highly conserved (88 per cent identity).
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Abstract The nucleotide sequences of IL-11 cDNAs cloned from mouse and man (mouse sequence submitted to GenBank, human sequence GenBank accession number M37006) encode proteins with 199 amino acids (Fig. 1) (Paul eta/. 1990). At the amino acid level, the mouse and human proteins are highly conserved (88 per cent identity).
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