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Interleukin-4 and interleukin-13 inhibit the expression of leukemia inhibitory factor and interleukin-11 in fibroblasts

Molecular Immunology, 2012
Cytokines produced by inflammatory or resident mesenchymal cells play important modulatory roles in the pathogenesis of inflammation induced bone loss. In the present study, the effects of IL-4 and IL-13 on the expression of three osteotropic cytokines in the IL-6 family expressed in human gingival fibroblasts were studied.
Souza, Pedro P. C.   +7 more
openaire   +3 more sources

Effect of interleukin 11 on normal and pathological thrombopoiesis

Cancer Chemotherapy and Pharmacology, 1996
Interleukin 11 (IL-11) is a stromal cell-derived cytokine that has multiple effects on hematopoietic and nonhematopoietic systems. In vitro, it enhances the growth of early progenitors and promotes megakaryocytopoiesis and erythropoiesis. In healthy animals, IL-11 administration stimulates megakaryocyte maturation and increases peripheral platelet ...
M, Teramura   +4 more
openaire   +2 more sources

INTERLEUKIN-11 AND CARDIOVASCULAR PATHOLOGY

Molekulyarnaya Meditsina (Molecular medicine)
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. An important task in cardiology is the search and study of new biomarkers. Scientific interest is actively focused on the study of interleukin-11 (IL-11). The purpose of the literature review was to analyze experimental and clinical studies devoted to the study of IL-11 as a ...
A.M. Alieva   +4 more
openaire   +1 more source

[The role of interleukin-11 in osteosarcoma].

Der Pathologe, 2020
Osteosarcoma is an often highly malignant mesenchymal tumor. By definition, osteosarcoma cells are able to form osteoid, which can mature into tumor bone. Osteosarcoma metastasizes preferentially to the lung. In Europe, the incidence is between 2 and 5 new diagnoses per 1,000,000 people per year. The underlying mechanisms for osteosarcoma formation are
Juliane, Lokau   +2 more
openaire   +1 more source

Interleukin-11 and its receptor.

BioFactors (Oxford, England), 1993
Interleukin (IL)-11 is a bone marrow fibroblast derived cytokine with a wide spectrum of activities in different biological systems. It has been shown that IL-11 supports the growth of certain types of plasmacytoma and hybridoma cells, enhances antigen-specific antibody responses, synergizes with IL-3 in supporting megakaryocyte colony formation, acts ...
Y C, Yang, T, Yin
openaire   +1 more source

Interleukin‐11 in Respiratory Inflammation

Annals of the New York Academy of Sciences, 1995
O, Einarsson   +8 more
openaire   +2 more sources

Interleukin-11

1998
Paul F. Schendel, Katherine J. Turner
openaire   +1 more source

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod A Dudakov, Alan M Hanash
exaly  

Historical overview of the interleukin-6 family cytokine

Journal of Experimental Medicine, 2020
Sujin Kang   +2 more
exaly  

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