Results 171 to 180 of about 5,344,313 (294)

Interleukin 13 (IL-13) Signalling as a Potential Target for Cell Therapies in Liver Fibrosis. [PDF]

Int J Mol Sci
Mazurski A, Bednarz A, Czekaj P.
europepmc   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Unveiling the role of interleukin-13 in liver fibrosis of chronic hepatitis B patients: Development of a predictive model. [PDF]

PLoS One
Bestari MB, Wijaya MP, Girawan D, Agustanti N, Nugraha ES.   +4 more
europepmc   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profiling

JAAD Case Reports, 2022
Suzanne Xu, BS, Katelyn Singh, BA, Jennifer McNiff, MD, William Damsky, MD, PhD, Jeffrey R. Gehlhausen, MD, PhD   +4 more
doaj   +1 more source

Significant Contributions of Interleukin-13 Genotypes to Asthma Severity. [PDF]

In Vivo
Shen TC, Chen GL, Chen LH, Wang YC, Shih HY, Yang YC, Tsai CW, Chang WS, Hsia TC, Bau DT.   +9 more
europepmc   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Exploring the Association of Interleukin 13 Polymorphism (rs20541) and Serum Lipocalin 2 with Risk and Disability in Multiple Sclerosis. [PDF]

J Inflamm Res
Kamel FZ, El Shahawy AA, Abdelaziz EA, Mohamed EA, El Shahawy AA, Hassaneen AM, Khater AZ, Mokhtar GA, Boghdady WAH.   +8 more
europepmc   +1 more source

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis. [PDF]

Acta Derm Venereol, 2023
Ju T, Labib A, Nattkemper L, Engle S, Auxier A, Hahn N, Sissons S, Sims JT, Sun Z, Okragly AJ, Yosipovitch G.   +10 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source