Results 1 to 10 of about 885,440 (356)

Interleukin-17 in Antifungal Immunity [PDF]

Pathogens, 2019
The field of IL-17 biology has received much attention over the last decade owing to the pathogenic role of this cytokine in psoriasis and other autoinflammatory disorders and the successful implementation of IL-17-targeting therapies in patients ...
Florian Sparber, Salomé LeibundGut-Landmann   +1 more
doaj   +4 more sources

Giant Cell Arteritis Refractory to Interleukin‐6 and Interleukin‐17 Inhibition Treated With Upadacitinib [PDF]

ACR Open Rheumatology
Giant cell arteritis (GCA) is a granulomatous vasculitis that can involve both cranial and extracranial vessels. Although interleukin‐6 (IL‐6) receptor blockade is an established therapy, treatment options for medically refractory disease remain limited.
Luke S. Vest, Anam Ahmad, Sanhitha Valasareddy, Nancy Phillips, Adam Kilian   +4 more
doaj   +2 more sources

Efficacy of interleukin-17 inhibitors in psoriasis patients: a comparative non-randomized study [PDF]

Vestnik Dermatologii i Venerologii
Background. IL-17 blockers have expanded the possibilities of psoriasis therapy. Their high efficacy and safety profile have been demonstrated in phase I–III studies and in real-world clinical practice.
Arfenya E. Karamova, Anastasiia A. Vorontsova, Olga G. Artamonova   +2 more
doaj   +2 more sources

IL17A and IL17RA gene polymorphisms in Fanconi anemia [PDF]

Brazilian Oral Research, 2023
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia.
Rafael Zancan MOBILE, Monalisa Castilho MENDES, Cleber MACHADO-SOUZA, Priscila de Mattos QUEIROZ, Carmem Maria Sales BONFIM, Cassius Carvalho TORRES-PEREIRA, Juliana Lucena SCHUSSEL   +6 more
doaj   +1 more source

Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]

Cell Communication and Signaling
Background We previously identified Il17RB, a member of the IL17 superfamily, as a candidate marker gene for endometrial aging. While IL17RB has been linked to inflammation and malignancies in several organ systems, its function in the endometrium has ...
Keiko Kawamura, Yumiko Matsumura, Teruhiko Kawamura, Hiromitsu Araki, Norio Hamada, Kazutaka Kuramoto, Hiroshi Yagi, Ichiro Onoyama, Kazuo Asanoma, Kiyoko Kato   +9 more
doaj   +2 more sources

Levels of IL-23/IL-17 Axis in Plasma and Gingival Tissue of Periodontitis Patients According to the New Classification

Applied Sciences, 2022
Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño, Alondra del Carmen Ruiz-Gutiérrez, Vianeth María del Carmen Martínez-Rodríguez, Juan Ramón Gómez-Sandoval, Juan Manuel Guzmán-Flores, Julieta Sarai Becerra-Ruiz, Ana Lourdes Zamora-Perez, Celia Guerrero-Velázquez   +7 more
doaj   +1 more source

Interleukin 17 in early invasive breast cancer

Frontiers in Oncology, 2023
IntroductionInterleukin 17 (IL-17) has a key role in inflammatory responses. Increased serum concentrations of IL-17 have been reported in patients with different types of cancer.
Marina Popović, Marina Popović, Natalija Dedić Plavetić, Natalija Dedić Plavetić, Damir Vrbanec, Zlatko Marušić, Zlatko Marušić, Davor Mijatović, Davor Mijatović, Ana Kulić   +9 more
doaj   +1 more source

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

Frontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen, Sarah J. B. Snelling, Andrew J. Carr, Stephanie G. Dakin   +3 more
doaj   +1 more source

Relationship between interleukin 17 & 6 in patients with varicocele compare with a control group [PDF]

Journal of Medical and Life Science, 2019
The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male.
Hayder AL-Msaid, Waleed H., Hydar Khalfa
doaj   +1 more source

SELEX-discovered aptamer that inhibits cellular interleukin-17/interleukin-17 receptor interaction and antagonizes interleukin-17 signaling

Bioscience, Biotechnology, and Biochemistry, 2023
ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi, Tong Wang, Yukio Takamori, Takehiro Ando, Takumi Yokoyama, Daisuke Fuji, Zhehao Xu, Santhana Vedi, Mizuki Yamamoto, Keita Tsukamoto, Takashi Kawakami   +10 more
openaire   +2 more sources