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The Treatment with Interleukin 17 Inhibitors and Immune-Mediated Inflammatory Diseases
Current Issues in Molecular Biology, 2022 IL-17 inhibitors (IL-17i) are medicines used to treat dermatological and rheumatic diseases They belong to a class of medicines called biological disease-modifying anti-rheumatic drugs (bDMARDs).
Laura Țiburcă +6 more
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Faecalibacterium prausnitziiinhibits interleukin-17 to ameliorate colorectal colitis in rats [PDF]
, 2014 © 2014 Zhang et al. Results: The culture supernatant of F. prausnitzii increased plasma anti-Th17 cytokines (IL-10 and IL-12) and suppressed IL-17 levels in both plasma and colonic mucosa, with ameliorated colonic colitis lesions.
Chen, H +7 more
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Role of IL-33 in inflammation and disease [PDF]
, 2011 Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inflammatory stimulation.
Miller, Ashley M.
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Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]
, 2020 Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
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Interleukin-17: A Revisited Study [PDF]
International Journal of Immunopathology and Pharmacology, 2004 Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses.
HUANG SH +14 more
openaire +3 more sources
Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
Advanced Biomedical Research, 2014 Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani +4 more
doaj +1 more source
The effect of carbohydrate ingestion on the Interleukin-6 response to a 90-minute run time trial [PDF]
, 2009 Fatigue is a predictable outcome of prolonged physical activity; yet its biological cause remains uncertain. During exercise, a polypeptide messenger molecule interleukin- 6 (IL-6) is actively produced.
Ansley, Les +3 more
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Airway neutrophils and interleukin-17 [PDF]
European Respiratory Journal, 2000 It is well known that exacerbations of obstructive airways disease such as asthma and chronic obstructive pulmonary disease are associated with an increased number of neutrophils in the airways. However, the mechanisms behind this phenomenon are poorly understood.
A, Lindén, H, Hoshino, M, Laan
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]
, 1998 Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Cremer, Peter +8 more
core +1 more source