Results 241 to 250 of about 387,985 (305)

Case Report: Interleukin-23 blockade achieves sustained remission in Niemann-Pick type C-associated Crohn's disease refractory to anti-tumor necrosis factor therapy. [PDF]

Front Immunol
Kakiuchi T, Shimada S, Zhang Y, Nomura M, Yoshiura M.   +4 more
europepmc   +1 more source

Comparison of the Effects and Safety of Planned Limited-Time Withdrawal Versus Continuous Maintenance of Interleukin Inhibitors in Patients with Psoriasis: A Systematic Review and Network Meta-Analysis. [PDF]

Dermatol Ther (Heidelb)
de Sena RR, de C Mesquita K, Barroso LF, Canabrava PBE, Zanghelini F, Gomes CM.   +5 more
europepmc   +1 more source

Interleukin (IL)-17A Inhibitor as a Treatment for Darier Disease in the Pediatric Population. [PDF]

Cureus
Barajas Mendez BD, Maldonado-Colin G, Achell Nava L, Rosas Garcia MR, Rivas Antonio A.   +4 more
europepmc   +1 more source

Mortality incidence in spondyloarthritis: real-world evidence using the TriNetX Global Collaborative Network. [PDF]

RMD Open
Llop M, Rodrigo-Parés A, Saus E, Moreno M, Arévalo M, Cabanillas M, Gratacós J, Calvet J.   +7 more
europepmc   +1 more source

Application of Trichoscopy and Novel Non-Invasive Imaging Techniques in the Diagnosis and Management of Patients with Scalp Psoriasis. [PDF]

Psoriasis (Auckl)
Kuchnicka A, Fałkowska U, Konopelski P, Anderson A, Rakowska A, Kurzeja M, Olszewska M, Rudnicka L.   +7 more
europepmc   +1 more source

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Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

Nature, 1990
Three interleukin-1 inhibitors have been purified to homogeneity from medium conditioned by human monocytes. Partial sequence analysis and digestion with N-glycanase indicate that these are glycosylation forms of a single protein. The protein binds to the interleukin-1 receptor but has no interleukin-1-like activity, even at very high concentrations ...
C H, Hannum, C J, Wilcox, W P, Arend, F G, Joslin, D J, Dripps, P L, Heimdal, L G, Armes, A, Sommer, S P, Eisenberg, R C, Thompson   +9 more
openaire   +4 more sources

CLINICAL UTILITY OF INTERLEUKIN-1 INHIBITORS IN PEDIATRIC SEPSIS

Shock, 2023
ABSTRACT The pathophysiology of pediatric sepsis is characterized by increased innate immune activation earlier in life. Interleukin-1 is a proinflammatory cytokine implicated in the pathophysiology of sepsis, and ferritin is a stable surrogate biomarker for elevated IL-1 levels.
Ravi, Manchikalapati, Jonathon, Schening, Andrew J, Farias, Keith A, Sacco   +3 more
openaire   +2 more sources

Human Urine-Derived Inhibitors of Interleukin 1

Clinical Infectious Diseases, 1987
Human urine has been found to contain several different substances that are capable of inhibiting the in vitro effects of interleukin 1 (IL-1). The urine of febrile individuals contains elevated levels of a 30-40 kilodalton (kdal) glycoprotein that is a potent inhibitor of IL-1-induced proliferation of murine thymocytes.
D L, Rosenstreich, S L, Yost, K M, Brown
openaire   +2 more sources