Results 321 to 330 of about 158,089 (347)
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Intracellular Interleukin-1 Receptor Antagonist in Osteoarthritis Chondrocytes

Clinical Orthopaedics and Related Research, 2003
The objective of the current study was to determine whether the balance of interleukin-1 and intracellular interleukin-1 receptor antagonist in chondrocytes in osteoarthritic human joints favors agonist action. Chondrocytes were isolated from cartilage specimens taken at the time of joint arthroplasty.
Junichi Hirahashi   +4 more
openaire   +2 more sources

The Treatment of Sepsis with Interleukin-1 Receptor Antagonist

1994
Compelling experimental evidence and considerable clinical experience indicate that the proinflammatory cytokines are central to the pathogenesis of septic shock [1, 2]. Interleukin-1 (IL-1) and tumor necrosis factor-α (TNF) play an essential protective role in the priming and initiation of the host innate and acquired immune response to localized ...
John Pribble, S. M. Opal, C. J. Fisher
openaire   +2 more sources

Interleukin-1 receptor antagonist: Discovery, structure and properties

Progress in Growth Factor Research, 1990
Interleukin-1 receptor antagonist (IL-1ra) is a recently-described member of the IL-1 family. This unique human protein has 30% amino acid sequence homology to IL-1 beta and binds to human types I and II IL-1 receptors without apparent cellular activation.
openaire   +3 more sources

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-vornhagen   +2 more
exaly  

Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)

2019
Deficiency of the interleukin-1 receptor antagonist IL-1Ra (DIRA) is a very rare and severe autoinflammatory disease associated with loss of function mutations in the IL1RN gene. Inflammation results from unopposed signaling by IL-1α and IL-1β. DIRA presents mostly in the neonatal period with systemic inflammation and characteristic skin pustulosis and
openaire   +2 more sources

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

A review of cancer immunotherapy toxicity

Ca-A Cancer Journal for Clinicians, 2020
Lucy Boyce Kennedy
exaly  

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel   +2 more
exaly  

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