Results 151 to 160 of about 628,146 (183)
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Recombinant interleukin-1 receptor antagonist protein prevents sensitization and intestinal anaphylaxis in Guinea pigs

Life Sciences, 1993
Recombinant interleukin-1 receptor antagonist protein (rlRAP, 0.5 mg/kg) administered intraperitoneally in guinea pigs one hour before primary and booster parenteral sensitization (1 ml) by cow milk, led to a reduced immunoglobulin E (IgE) production, as displayed by a passive cutaneous anaphylaxis test.
Theodorou, Vassilia   +2 more
openaire   +4 more sources

Characterization of an interleukin 1 receptor antagonist protein released from ultraviolet-irradiated epidermal sheet

Journal of Dermatological Science, 1997
An interleukin 1 (IL-1) inhibitor was detected in the culture supernatant of mouse epidermal sheet which had been irradiated with middle-wavelength ultraviolet (UVB) either in vitro or in vivo. Properties of the IL-1 inhibitor were consistent with those of IL-1 receptor antagonist (IL-1ra), i.e., approximate molecular size of 17 kDa by gel filtration ...
Hideyuki Ichikawa   +3 more
openaire   +3 more sources

Reduced muscle protein breakdown in septic rats following treatment with interleukin-1 receptor antagonist

International Journal of Biochemistry, 1994
1. The role of interleukin-1 (IL-1) in sepsis-induced muscle proteolysis was assessed by treating septic rats with recombinant IL-1 receptor antagonist (rIL-1ra). 2. In initial experiments, we tested the effectiveness of IL-1ra in preventing muscle proteolysis induced by administration of IL-1. 3.
Robert Thompson   +5 more
openaire   +3 more sources

SEPSIS INHIBITS SYNTHESIS OF MYOFIBRILLAR AND SARCOPLASMIC PROTEINS

Shock, 1996
The breakdown of myofibrillar and sarcoplasmic (nonmyofibrillar) proteins are regulated independently in sepsis, however, the factors regulating their synthesis are unknown. In this study, we assessed the effects of sepsis and interleukin-1 receptor antagonist on sarcoplasmic and myofibrillar protein synthesis in gastrocnemius. The rate of sarcoplasmic
Jeanette K. Beers   +4 more
openaire   +2 more sources

Combined Treatment of Acute EAE in Lewis Rats with TNF-Binding Protein and Interleukin-1 Receptor Antagonist

Experimental Neurology, 1998
Experimental autoimmune encephalomyelitis (EAE) is a term given to describe a collection of animal models representing the human disease multiple sclerosis (MS). Although not fully understood, the involvement of cytokines and the immune system in either EAE or human MS is well established.
S. Ogenstad   +7 more
openaire   +2 more sources

The effects of interleukin-1 receptor antagonist protein (IRAP) infusion following spinal cord transection in rats

Molecular and Chemical Neuropathology, 1996
A laminectomy was performed at the T5-T6 vertebral level in adult, male, Sprague-Dawley rats and the spinal cord transected with a scalpel. A group of sham animals was subjected to the same surgery without the transection step. A group of unhandled control rats was also included. A subgroup of transected animals received a subcutaneous osmotic minipump
Cecilia Ferrer   +5 more
openaire   +3 more sources

Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration

Knee Surgery, Sports Traumatology, Arthroscopy, 2015
Jennifer M. Cassano   +5 more
semanticscholar   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-vornhagen   +2 more
exaly  

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