Results 211 to 220 of about 148,492 (237)
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Potential agonist action of the interleukin-1 receptor antagonist protein: implications for treatment of women.

The Journal of Clinical Endocrinology & Metabolism, 1993
The interleukin-1 receptor antagonist protein (IRAP) caused a concentration-related increase in prostaglandin production by human decidual cells. The degree and time course of this stimulatory action were identical to those induced by interleukin 1 beta (IL-1 beta).
Mitchell, M.D.   +3 more
openaire   +3 more sources

Interleukin-1 beta induces interleukin-1 receptor antagonist and tumor necrosis factor binding protein in humans.

Cancer research, 1993
Sustained release or high levels of interleukin-1 (IL-1) and/or tumor necrosis factor (TNF), as observed after endotoxin challenge, can produce a variety of toxicities. Naturally occurring inhibitors to IL-1 and TNF, IL-1 receptor antagonist (IL-1ra) and soluble TNF receptor forms, have been detected.
M J, Bargetzi   +6 more
openaire   +1 more source

The effects of interleukin-1 receptor antagonist protein (IRAP) infusion following spinal cord transection in rats

Molecular and Chemical Neuropathology, 1996
A laminectomy was performed at the T5-T6 vertebral level in adult, male, Sprague-Dawley rats and the spinal cord transected with a scalpel. A group of sham animals was subjected to the same surgery without the transection step. A group of unhandled control rats was also included. A subgroup of transected animals received a subcutaneous osmotic minipump
J B, Gelderd   +5 more
openaire   +2 more sources

Beneficial Effect of Interleukin-1 Receptor Antagonist Protein on Spinal Cord Injury Recovery in the Rat

Inflammation, 2011
We assessed the effect of treatment with the interleukin-1 receptor antagonist protein (IRAP) on morphological and functional recovery in a rat model of SCI. All sections were processed for immunohistochemistry, hematoxylin-eosin, and Nissl staining. Rats were assessed for hind limb motor function using the Basso, Beattie, and Bresnahan (BBB) hind limb
Shaohui, Zong   +4 more
openaire   +2 more sources

[Using process of refolding the protein to obtain recombinant human interleukin-1 receptor antagonist].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2009
Recombinant human interleukin-1 receptor antagonist was expressed in E. coli as an insoluble inclusion body. The inclusion body was dissolved in the 8 M urea and then the solution was diluted untill the concentration of urea became 2 M. By ion exchange chromatography the protein in the solution of 2 M urea was refolded and purified.
Shugang, Li   +6 more
openaire   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen   +2 more
exaly  

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

New England Journal of Medicine, 2021
Anthony C Gordon   +2 more
exaly  

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