Results 31 to 40 of about 32,812,329 (299)

Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. [PDF]

Journal of Clinical Investigation, 1997
Interleukin 1 receptor antagonist (IL-1Ra) levels are elevated in the blood of patients with a variety of infectious, immune, or traumatic conditions. To examine whether IL1Ra is produced by liver cells with characteristics resembling an acute-phase protein, human primary hepatocytes isolated from liver biopsies and HepG2 hepatoma cells were stimulated
C, Gabay, M F, Smith, D, Eidlen, W P, Arend   +3 more
openaire   +2 more sources

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Pfeilschifter, Josef, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Koehl, Ulricke, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +40 more
core   +1 more source

Host genome polymorphisms and tuberculosis infection: What we have to say?

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Several epidemiology studies suggest that host genetic factors play important roles in susceptibility, protection and progression of tuberculosis infection.
Said Alfin Khalilullah, Harapan Harapan, Nabeeh A. Hasan, Wira Winardi, Ichsan Ichsan, Mulyadi Mulyadi   +5 more
doaj   +1 more source

Helicobacter pylori Seropositivity in Patients with Interleukin-1 Polymorphisms Is Significantly Associated with ST-Segment Elevation Myocardial Infarction. [PDF]

PLoS ONE, 2016
Helicobacter pylori infection and interleukin-1 polymorphisms are associated with an increased risk of gastric cancer. We examined the prevalence of Helicobacter pylori seropositivity and interleukin-1 polymorphisms between ST-segment elevation ...
Noriaki Tabata, Daisuke Sueta, Tomonori Akasaka, Yuichiro Arima, Kenji Sakamoto, Eiichiro Yamamoto, Yasuhiro Izumiya, Megumi Yamamuro, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Kazunori Morita, Kentaro Oniki, Junji Saruwatari, Kazuko Nakagawa, Seiji Hokimoto   +15 more
doaj   +1 more source

The experimental treatment of corneal graft rejection with the interleukin-1 receptor antagonist (IL-1ra) gene. [PDF]

PLoS ONE, 2013
PURPOSE: To investigate the protective effects of interleukin-1 receptor antagonist (IL-1ra) gene transfer in a rat model of corneal graft rejection.
Jin Yuan, Yi Liu, Weilan Huang, Shiyou Zhou, Shiqi Ling, Jiaqi Chen   +5 more
doaj   +1 more source

Identification of Suitable Drug Combinations for Treating COVID-19 Using a Novel Machine Learning Approach: The RAIN Method

Life, 2022
COVID-19 affects several human genes, each with its own p-value. The combination of drugs associated with these genes with small p-values may lead to an estimation of the combined p-value between COVID-19 and some drug combinations, thereby increasing ...
Aliakbar Kiaei, Nader Salari, Mahnaz Boush, Kamran Mansouri, Amin Hosseinian-Far, Hooman Ghasemi, Masoud Mohammadi   +6 more
doaj   +1 more source

The Clinical Significance of Interleukin-1 Receptor Antagonist +2018 Polymorphism in Rheumatoid Arthritis. [PDF]

PLoS ONE, 2016
Interleukin-1 receptor antagonist (IL-1Ra) acts as an inhibitor of IL-1; which is one of the culprit cytokines in rheumatoid arthritis (RA). Although +2018 polymorphism of IL-1Ra has been implicated in the pathogenesis of RA, its importance remains ...
Endom Ismail, Omimah Khaled Jaber Nofal, Rajalingham Sakthiswary, Syahrul Sazliyana Shaharir, Radhika Sridharan   +4 more
doaj   +1 more source

Induction of the interleukin 1 receptor antagonist protein by transforming growth factor‐β

European Journal of Immunology, 1991
AbstractTransforming growth factor‐β1 (TGF‐β1) mediates many immunosuppressive effects on immune cells and can inhibit the production of tumor necrosis factor and interleukin 1 (IL 1). However, TGF‐β1 can stimulate the production of IL6 and platelet‐derived growth factor, indicating that TGF‐β1 initiates complex effects on the production of cytokines ...
Turner, M, Chantry, D, Katsikis, P, Berger, A, Brennan, F, Feldmann, M   +5 more
openaire   +2 more sources

Soluble interleukin‐1 receptor accessory protein ameliorates collagen‐induced arthritis by a different mode of action from that of interleukin‐1 receptor antagonist [PDF]

Arthritis & Rheumatism, 2005
AbstractObjectiveTo discern the mode of interleukin‐1 (IL‐1) inhibition of soluble IL‐1 receptor accessory protein (sIL‐1RAcP) by comparison with IL‐1 receptor antagonist (IL‐1Ra) in arthritis.MethodsAdenoviral vectors encoding either sIL‐1RAcP or IL‐1Ra were administered systemically before onset of collagen‐induced arthritis in DBA/1 mice.
Smeets, R.L.L., Joosten, L.A.B., Arntz, O.J., Bennink, M.B., Takahashi, N., Carlsen, H., Martin, M.U., Berg, W.B. van den, Loo, F.A.J. van de   +8 more
openaire   +3 more sources

SUPERSEDED - Supplementary Figures: Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence

, 2019
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2626 ## Supplementary Figures from the manuscript "Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti ...
McCulloch, Laura
core   +1 more source