Results 11 to 20 of about 98,375,777 (262)
In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system [PDF]
, 2006 We have used the tetracycline (tet)-regulated system as described previously to evaluate the applicability of controlled gene expression in cancer gene therapy. As a model gene, we used the human interleukin-2 (IL-2) gene, which has been placed under the Wirth, Thomas, Schindowski, Katharina, Zöller, Margot, Pomer, Sigmund, Pitzer, Claudia +4 morecore +1 more sourceInterleukin-18 [PDF]
, 2003 Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.McInnes, I.B., Robertson, S.E., Gracie, J.A. +2 morecore +1 more sourceHuman Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro
Bioengineering, 2020 High-dose recombinant interleukin 2 (IL2) therapy has been shown to be successful in renal cell carcinoma and metastatic melanoma. However, systemic administration of high doses of IL2 can be toxic, causing capillary leakage syndrome and stimulating pro ...Daria S. Chulpanova, Valeriya V. Solovyeva, Victoria James, Svetlana S. Arkhipova, Marina O. Gomzikova, Ekaterina E. Garanina, Elvira R. Akhmetzyanova, Leysan G. Tazetdinova, Svetlana F. Khaiboullina, Albert A. Rizvanov +9 moredoaj +1 more sourceInterleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]
, 2012 BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.Thomas, GN, Willeit, P, Trip, MD, Willeit, J, Nelson, Christopher P, Samani, NJ, Danesh, J, Psaty, Bruce M., Assimes, Themistocles L., Stringham, Heather M, Kastelein, JJP, Adamovic, Svetlana, Franks, Paul W., Trip, Mieke D, Harris, Tamara B, Meade, TW, Thomas, Graham; id_orcid, Tivesten, A, de Bakker, PIW, Tybjærg-Hansen, Anne, Boehnke, M, de Bakker, Paul IW, Wilson, Anthony G, Trip, Mieke D., Witteman, Jacqueline C. M., Freitag, DF, Sarwar, Nadeem, Gao, P, Gallacher, John Edward, Ljunggren, Osten, Qi, Lu, Hall, Alistair S., Samani, Nilesh J., Karlsson, Magnus, Hofman, Bert, Goodall, AH, Watkins, H, Arbor, Ann, Davey Smith, George, Chambers, John C, Shaffer, Jonathan A, Butterworth, Adam S., Tracy, Russell P, O'Donnell, CJ, Gorman, Donal N., Psaty, Bruce M, Panagiotakos, DB, Wilde, Arthur AM, Best, LG, Di Angelantonio, Emanuele, Sundstrom, J, Butterworth, AS, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.), Cambien, Francois, Gregson, J, Gorman, Donal N, Best, Lyle G., Manson, JE, Rimm, Eric B, Wennberg, P, de Bakker, Paul I. W., Melzer, D, Qi, L, Gillum, Richard F, Kleber, ME, Gallacher, John, Kastelein, John JP, Chasman, DI, Cambien, F, Ridker, Paul M, Salomaa, Veikko, Hall, AS, Benjamin, Emelia J., Chasman, Daniel I, Salonen, JT, Kaptoge, S, Salonen, Jukka T., O'Donnell, Christopher J., Ingelsson, Erik, Benjamin, Emelia J, Freitag, Daniel F, Rader, Daniel J., Tracy, Russell P., Salonen, Jukka T, Saleheen, D, ?, ?, Salomaa, V, Clarke, Robert, Kleber, Marcus E., Chambers, JC, Witteman, Jacqueline C M, Braund, Peter S., Manson, JoAnn E., Boehnke, Michael, Ouwehand, Willem H, Rendon, A, Wilson, Anthony G., Harari, Olivier, Hopewell, Jemma C., Wilson, AG, Tracy, RP, Karlsson, M, Cantin, B, Reilly, Muredach P., Ohlsson, C, Melzer, David, IL6R Genetics Consortium Emerging Risk Factors Collaboration, Meade, Tom W, Benjamin, EJ, Stringham, Heather M., Freitag, Daniel F., Cantin, Bernard, Gregson, John, Chasman, Daniel I., Butterworth, Adam S, Reich, David, Braund, PS, Schunkert, H, Di Angelantonio, E, Ouwehand, WH, Harris, Tamara B., Thomas, G. Neil, Allin, Kristine H., Nelson, CP, Allin, Kristine Højgaard, Best, Lyle G, de Faire, Ulf, Davey-Smith, George, Kooner, Jaspal S, Gudnason, Vilmundur, Rimm, Eric B., Shaffer, Jonathan A., Sundstrom, Johan, Jansson, JO, Erdmann, Jeanette, Steri, M, Kauhanen, J, Holm, H, Samani, Nilesh J, Nordestgaard, BG, Mellstrom, Dan, Rader, Daniel J, Kaptoge, Stephen, Goodall, Alison H., Meade, Tom W., Clarke, R, Shaffer, JA, Ben-Shlomo, Yoav, Wilson, James F, Witteman, JCM, Ridker, PM, Davey-Smith, G, Tivesten, Asa, Koenig, W, Franks, Paul W.,, O'Donnell, Christopher J, Allin, Kristine H, van der Schoot, CE, Reilly, MP, Asselbergs, FW, Nelson, Christopher P., Hung, J, Danesh, John, Witteman, Jacqueline CM, Gudnason, V, Adamovic, S, Holm, Hilma, Kleber, Marcus E, Cushman, M, Ljunggren, Östen,, Erdmann, J, Koenig, Wolfgang, Rimm, EB, Hung, Joseph, Asselbergs, Folkert W., van der Schoot, C. Ellen, Wassertheil-Smoller, S, Kooner, Jaspal S., Panagiotakos, Demosthenes B, Franks, Paul, Willeit, Peter, Nordestgaard, Børge G, Kooner, JS, Chambers, John C., Tybjaerg-Hansen, Anne, Nordestgaard, Borge G., Tybjaerg-Hansen, A, Kauhanen, Jussi, Wilde, Arthur A. M., Gillum, RF, Watkins, Hugh, Mellstrom, D, Thomas, G Neil, Sarwar, N, de Faire, U, Wilde, AAM, Psaty, BM, Ben-Shlomo, Y, Panagiotakos, Demosthenes B., Ljunggren, O, Harris, TB, Sundström, Johan,, Reilly, Muredach P, Wilde, Arthur A M, Asselbergs, Folkert W, Woodward, Mark, Stringham, HM, Harari, O, Saleheen, Danish, Schunkert, Heribert, Hall, Alistair S, Cushman, Mary, Gorman, DN, Gillum, Richard F., Hopewell, Jemma C, Wilson, JF, IL6R Genetics Consortium, Rader, DJ, Wilson, James F., Kastelein, John J. P., Woodward, M, Hopewell, JC, Hofman, Albert, Rendon, Augusto, Wennberg, Patrik, Jansson, John-Olov, Wilhelmsen, L, Reich, D, Manson, JoAnn E, Onat, A, Amouyel, Philippe, Hamsten, A, Ingelsson, E, Franks, Paul W, Willeit, Johann, Onat, Altan, Wilhelmsen, Lars, Assimes, Themistocles L, Gallacher, J, Wassertheil-Smoller, Sylvia, van der Schoot, C Ellen, Assimes, TL, Goodall, Alison H, Franks, PW, Amouyel, P, Steri, Maristella, Ohlsson, Claes, Braund, Peter S, Allin, KH, Hamsten, Anders, Ridker, Paul M., Ouwehand, Willem H., Gao, Pei, Uitterlinden AG, Stark K, Asselbergs FW, Gregson J, Baumert J, Böhm BO, Kleber ME, Butterworth AS, de Jong JS, Yarnell JW, Danesh J. Collaborators Assimes TL, Wennberg P, Rimm EB, Preuss M, Qi L, Ripatti S, Stefanadis C, Smith AV, Ben Shlomo Y, Rasheed A, Ridker PM, Goodall AH, Karlsson, Magnus,, Kuusisto J, Tikkanen E, Rose LM, Perola M, Dupuis J, Armitage J, Mukamal KJ, Wilson JF, Nordestgaard BG, Hu FB, Jula A, Cheng KK, Reich D, Thorsteinsdóttir U, Thompson PL, Quertermous T, Nieminen MS, Illig T, Lind L, Gallacher J, Tivesten Å, Basu S, Mellström D, Stringham HM, Winkelmann BR, Silveira A, Tivesten, Åsa,, O'Donnell CJ, Whincup PH, Arveiler D, Morris RW, Guralnik JM, Sinisalo J, Maiwald S, Scharnagl H, Jansson JH, van der Schouw YT, Jansson JO, Tuomainen TP, Chasman DI, Freitag DF, Hengstenberg C, Tracy RP, Peden JF, Dehghan A, Fontes JD, Lam TH, Gigante B, Sivapalaratnam S, Hall AS, Harris TB, Lund University., Laakso M, Wilde AA, Nahrstaedt J, Deloukas P, Dagenais GR, Sarwar N, Qu L, Hofman A, Benjamin EJ, Loley C, Kastelein JJ, Rumley A, Heckbert SR, Koenig IR, Beilby JP, Clarke R, Bezzina CR, Amouyel P, Howard BV, Kaptoge S, de Bakker PI, Willenborg C, Shungin D, Schunkert H, Wassertheil Smoller S, Gillum RF, Barroso I, Mellström, Dan,, Gao P, Di Angelantonio E, Tuomilehto J, Cantin B, Shaffer JA, Jansson, John-Olov,, Ingelsson E, Männistö S, Knowles JW, Wilhelmsen L, Singleton AB, Koenig W, Chambers JC, Das D, Davidson KW, Psaty BM, Willeit J, Willeit P, Hlatky MA, Hankinson SE, Schreiber S, Wiggins KL, Panagiotakos DB, Dekker LR, Salonen JT, Manson JE, Thomas GN, Watkins H, Lokki ML, Pai J, Ljunggren Ö, McQuillan BM, Buring J., Adamovic, Svetlana,, Go AS, Gorman DN, Boehnke M, Bis JC, Witteman JC, Adamovic S, Sheikh N, Havulinna AS, Thorleifsson G, Reilly MP, Folsom AR, Sanna S, Fraser R, Meisinger C, Karlsson MK, Kauhanen J, Li M, van Duijn CM, Cambien F, Samani NJ, Davey Smith G, Assimes TL, de Faire U, Meade TW, van der Schoot CE, Verschuren WM, Ohlsson, Claes,, Motazacker M, Allin KH, Sabater Lleal M, Smith NL, Danesh J, Jackson A, Kurl S, Tanck M, Shea SJ, Yin X, Kooner JS, Collins R, Zhang W, Steri M, Thorand B, Saleheen D, CUCCA, Francesco, Gudnason V, Harari O, Melzer D, Onat A, Best LG, Tybjærg Hansen A, Nelson CP, Onland Moret NC, Franks PW, Rosengren A, Karlsson M, Erdmann J, Basart H, Wannamethee SG, Salomaa V, Ouwehand WH, Trip MD, Woodward M, Rendon A, Parish S, Balmforth AJ, Braund PS, Stefansson K, Abecasis GR, Ohlsson C, Sundström J, Hveem K, Hólm H, Ferrucci L, Syvänen AC, Hallmans G, Hopewell JC, Lowe G, Pitsavos C, Kiechl S, Farrall M, Thorgeirsson G, Hamsten A, Rader DJ, Boer JM, Franks, Paul,, Jiang CC, Chrysohoou C, Hung J, Bandinelli S, Schlessinger D, März W, Uda M, Cushman M, Wilson AG, Thompson JR, Qasim A, Sarwar, N;Butterworth, AS;Freitag, DF;Gregson, J;Willeit, P;Gorman, DN;Gao, P;Saleheen, D;Rendon, A;Nelson, CP;Braund, PS;Hall, AS;Chasman, DI;Tybjærg-Hansen, A;Chambers, JC;Benjamin, EJ;Franks, PW;Clarke, R;Wilde, AA;Trip, MD;Steri, M;Witteman, JC;Qi, L;van der Schoot, CE;de Faire, U;Erdmann, J;Stringham, HM;Koenig, W;Rader, DJ;Melzer, D;Reich, D;Psaty, BM;Kleber, ME;Panagiotakos, DB;Willeit, J;Wennberg, P;Woodward, M;Adamovic, S;Rimm, EB;Meade, TW;Gillum, RF;Shaffer, JA;Hofman, A;Onat, A;Sundström, J;Wassertheil-Smoller, S;Mellström, D;Gallacher, J;Cushman, M;Tracy, RP;Kauhanen, J;Karlsson, M;Salonen, JT;Wilhelmsen, L;Amouyel, P;Cantin, B;Best, LG;Ben-Shlomo, Y;Manson, JE;Davey-Smith, G;de Bakker, PI;O'Donnell, CJ;Wilson, JF;Wilson, AG;Assimes, TL;Jansson, JO;Ohlsson, C;Tivesten, Å;Ljunggren, Ö;Reilly, MP;Hamsten, A;Ingelsson, E;Cambien, F;Hung, J;Thomas, GN;Boehnke, M;Schunkert, H;Asselbergs, FW;Kastelein, JJ;Gudnason, V;Salomaa, V;Harris, TB;Kooner, JS;Allin, KH;Nordestgaard, BG;Hopewell, JC;Goodall, AH;R, Campbell H, Wild S, Kooner AS +489 morecore +1 more sourceOncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy
Molecular Therapy: Oncolytics, 2017 Adoptive cell therapy holds much promise in the treatment of cancer but results in solid tumors have been modest. The notable exception is tumor-infiltrating lymphocyte (TIL) therapy of melanoma, but this approach only works with high-dose ...Riikka Havunen, Mikko Siurala, Suvi Sorsa, Susanna Grönberg-Vähä-Koskela, Michael Behr, Siri Tähtinen, João Manuel Santos, Pauliina Karell, Juuso Rusanen, Dirk M. Nettelbeck, Anja Ehrhardt, Anna Kanerva, Akseli Hemminki +12 moredoaj +1 more sourcePriming by recombinant chicken interleukin-2 induces selective expression of IL-8 and IL-18 mRNA in chicken heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enterica serovar enteritidis [PDF]
, 2003 Heterophils, the principal avian polymorphonuclear leukocytes (PMNs) equivalent to the mammalian neutrophil, function as professional phagocytes against bacterial infections, mediate acute inflammation, and respond to cytokine stimulation to aid in ...Michael H Kogut, Pete Kaiser, Kogut, Michael H, Kaiser, Pete, Lisa Rothwell, Rothwell, Lisa +5 morecore +1 more source
