Results 71 to 80 of about 22,989,400 (391)

Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome

open access: yesMediators of Inflammation, 2006
The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers ...
Daria Simcic   +5 more
doaj   +2 more sources

A modified assay for measuring thymocyte co-stimulatory activity

open access: yesMemorias do Instituto Oswaldo Cruz, 1993
The observation that murine thymocytes increase their proliferation to interleukin 1 (IL-1) in the presence of phytohemagglutinin (PHA) when pre-incubated with interleukin 2 (IL-2) allowed the introduction of a modified assay for the measurement of IL-1 ...
Sergio R. Dalmau   +2 more
doaj   +1 more source

Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population

open access: yesBMC Medical Genetics, 2020
Background Intervertebral disc degeneration (IVDD) is an age-related degenerative disease, presenting with low back pain or radicular pain. The inflammatory changes would occur in discs in the process of IVDD.
Sara Hanaei   +6 more
doaj   +1 more source

Interleukin-2 and regulatory T cells in graft-versus-host disease.

open access: yesNew England Journal of Medicine, 2011
BACKGROUND Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for Treg cell growth, survival, and activity.
J. Koreth   +17 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Co-stimulation of the fc receptor and interleukin-12 receptor on human natural killer cells leads to increased expression of cd25

open access: yesOncoImmunology, 2018
Natural killer (NK) cells serve a critical role in the immune response against microbes and developing tumors. We have demonstrated that NK cells produce stimulatory cytokines (e.g., IFN-γ) in response to potent stimulation via immobilized IgG (to engage
Megan C. Duggan   +9 more
doaj   +1 more source

The effect of carbohydrate ingestion on the Interleukin-6 response to a 90-minute run time trial [PDF]

open access: yes, 2009
Fatigue is a predictable outcome of prolonged physical activity; yet its biological cause remains uncertain. During exercise, a polypeptide messenger molecule interleukin- 6 (IL-6) is actively produced.
Ansley, Les   +3 more
core   +1 more source

Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy.

open access: yesBlood, 2014
Interleukin (IL)-2 promotes regulatory T-cell development and function, and treatment with IL-2 is being tested as therapy for some autoimmune diseases.
Frédéric Van Gool   +7 more
semanticscholar   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]

open access: yes, 1998
Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Cremer, Peter   +8 more
core   +1 more source

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