Results 51 to 60 of about 429,593 (156)
Interleukin-33 in Malignancies: Friends or Foes?
Frontiers in Immunology, 2018 The human Interleukin-33 (IL-33), a member of the IL-1 family, is the cytokine as a cell endogenous alarmin, released by damaged or necrotic barrier cells (endothelial and epithelial cells).
Jia-Xin Shen +5 more
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2016 Background: Recent evidence suggests that the interleukin-33/interleukin-1 receptor-like 1 (IL-33/IL1RL1) axis plays a critical role in autoimmune and inflammatory disorders; however, its mechanistic role in these diseases has not been clearly defined ...
Maryam Ahmadi +4 more
doaj
Red Blood Cells Store and Release Interleukin-33 [PDF]
Journal of Investigative Medicine, 2015 Interleukin-33 (IL-33) is a member of the IL-1 cytokine superfamily that potently drives production of a variety of cytokines and contributes to the pathogenesis of inflammatory diseases. The IL-33 is a nuclear protein and is released from apoptotic or necrotic cells.
Jianxin, Wei +6 more
openaire +2 more sources
IL33 in rheumatoid arthritis: potential contribution to pathogenesis
Revista Brasileira de ReumatologiaA better understanding of the inflammatory mechanisms of rheumatoid arthritis and the development of biological therapy revolutionized its treatment, enabling an interference in the synovitis – structural damage – functional disability cycle. Interleukin
Rafaela Bicalho Viana Macedo +2 more
doaj +1 more source
Interleukin-33 and ST2 Signaling in Tumor Microenvironment [PDF]
Journal of Interferon & Cytokine Research, 2019 Interleukin-33 (IL-33) is one of the members of the IL-1 family of cytokines and a ligand of ST2 and IL-1 receptor accessory protein (IL-1RAcP) that is known to affect Th2 inflammatory response with partial effects on Th1 responses. This cytokine is released by epithelial and smooth muscle cells of the airway system during their injury by several ...
Jaewoo, Hong +2 more
openaire +2 more sources
Higher interleukin-33 levels in aggressive periodontitis cases
Journal of Indian Society of Periodontology, 2019 Context: Interleukin-33 (IL-33) is a novel alarmin that warns immune cells of tissue destruction in injury or infection. Aims: This study is aimed at analyzing and correlating the concentration of IL-33 in the gingival crevicular fluid (GCF) and plasma ...
Sujatha Pai Ballambettu +3 more
doaj +1 more source
Interleukin-33: Its Emerging Role in Allergic Diseases
Molecules, 2018 Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world.
Wen Ding +5 more
doaj +1 more source
Interleukin-33 in Systemic Sclerosis: Expression and Pathogenesis
Frontiers in Immunology, 2018 Interleukin-33 (IL-33), a member of the IL-1 superfamily, functions as a traditional cytokine and nuclear factor. It is proposed to have an “alarmin” role. IL-33 mediates biological effects by interacting with the ST2 receptor and IL-1 receptor accessory
Liya Li +5 more
doaj +1 more source
IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria
Biochemistry and Biophysics Reports, 2016 IL-25, IL-33 and TSLP, which are produced predominantly by epithelial cells, can induce production of Th2-type cytokines such as IL-4, IL-5 and/or IL-13 by various types of cells, suggesting their involvement in induction of Th2-type cytokine-associated ...
Akiko Shibui +14 more
doaj +1 more source
Serum levels of Interleukin-33 and its soluble receptor ST2 in asthmatic patients
Egyptian Journal of Chest Disease and Tuberculosis, 2014 Interleukin-33 is a member of IL-1 family of cytokines and binds to two receptors: ST2 (IL-1-R1) and IL-1 receptor accessory protein (IL-1RAP). There are two isoforms of ST2 proteins: ST2L, a transmembrane form, and a soluble ST2 (sST2), a secreted form,
Ensaf A. Azazi +3 more
doaj +1 more source