Results 51 to 60 of about 728,843 (299)
CDX2 regulates interleukin‐33 gene expression in intestinal epithelial cells (LS174T)
FEBS Open Bio, 2021 Dysregulation of interleukin‐33 (IL‐33) has been implicated in the pathogenesis of several autoimmune and inflammatory diseases, but few studies have examined transcriptional regulation of the IL33 gene.
Sylvester Larsen +8 more
doaj +1 more source
Study of interleukin 33 in rheumatoid arthritis versus osteoarthritis patients
Egyptian Rheumatology and Rehabilitation, 2017 Aim of the work To compare the expression of serum interleukin 33 (IL33), a new member of the interleukin1 (IL-1) cytokine family, in rheumatoid arthritis (RA) versus osteoarthritis (OA) patients and to correlate it with clinical, laboratory and ...
Aliaa M. Abd El-Aziz Farag +3 more
doaj +1 more source
Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]
, 2012 Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
A Kitamura +99 more
core +3 more sources
The ST2/Interleukin-33 Axis in Hematologic Malignancies: The IL-33 Paradox [PDF]
International Journal of Molecular Sciences, 2019 Interleukin (IL)-33 is a chromatin-related nuclear interleukin that is a component of IL-1 family. IL-33 production augments the course of inflammation after cell damage or death. It is discharged into the extracellular space. IL-33 is regarded as an “alarmin” able to stimulate several effectors of the immune system, regulating numerous immune ...
Allegra A. +6 more
openaire +4 more sources
Therapeutic Strategies for Targeting IL-33/ST2 Signalling for the Treatment of Inflammatory Diseases
Cellular Physiology and Biochemistry, 2018 Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in innate and adaptive immune responses via interaction with its receptor, ST2.
Wei-Yu Chen +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Current review of genetically modified lactic acid bacteria for the prevention and treatment of colitis using murine models [PDF]
, 2015 Inflammatory Bowel Diseases (IBD) are disorders of the gastrointestinal tract characterized by recurrent inflammation that requires lifelong treatments.
Azevedo, Vasco +7 more
core +1 more source
Association between interleukin‑33 and ovarian cancer
Oncology Reports, 2018 Ovarian cancer is the leading cause of cancer‑ associated mortality in the female reproductive system. Interleukin (IL)‑33 and its receptor IL 1 receptor like 1 (also termed ST2) are expressed by many cell types including epithelial cells. The role of IL‑33 in the pathogenesis of neoplasia remains controversial. The authors previously demonstrated that
Xiaoqing, Liu +11 more
openaire +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Journal of Indian Society of Periodontology, 2017 Background: Senescence is a multifactorial process that in humans may be accompanied by inflammation and immune dysfunction in the oral cavity. Notably, periodontal disease, considered one of the most common inflammatory disorders in the oral cavity, has
Wellington Francisco Rodrigues +4 more
doaj +1 more source