Results 1 to 10 of about 1,051,125 (350)
Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production [PDF]
Frontiers in ImmunologyCarbonic anhydrase (Car) enzymes are a family of metalloenzymes that are traditionally known for their ability to regulate pH and CO2 homeostasis. However, emerging studies now demonstrate that Car family members exhibit lineage-specific expression ...
Jianya Peng +23 more
doaj +2 more sources
Targeting interleukin 4 and interleukin 13: a novel therapeutic approach in bullous pemphigoid [PDF]
Annals of Medicine, 2023 Aim: Bullous pemphigoid (BP) is an organ-specific autoimmune bullous disease characterized by autoantibodies that target the cellular adhesion molecules BP180 and BP230.
Fangyuan Chen +4 more
doaj +2 more sources
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]
, 1990 BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
M D Sadick +5 more
openalex +4 more sources
Interleukin-4 and its receptor alpha in paediatric uncomplicated malaria patients from a Ghanaian case-control study [PDF]
BMC Research NotesObjectives This study investigated gene polymorphisms in the interleukin-4 (IL-4) and its receptor alpha (IL-4Rα) gene regions in human hosts with uncomplicated malaria.
Patrick Diaba-Nuhoho
doaj +2 more sources
Interleukin-4 receptor alpha gene variants and allergic disease [PDF]
Respiratory Research, 2000 The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to the risk of developing asthma in a given individual.
Hall Ian P
doaj +3 more sources
Evaluation of room temperature (30°C to 35°C) lyophilized vaccine with radio inactivated Mannheimia haemolytica whole cells isolated from infected sheep [PDF]
Veterinary World, 2022 Background and Aim: Vaccines are one of the important tools for fighting diseases and limiting their spread. The development of vaccines with high efficacy against diseases is essential.
Sahar Ahmed +4 more
doaj +1 more source
Bone & Joint Research, 2021 Aims: The use of 3D-printed titanium implant (DT) can effectively guide bone regeneration. DT triggers a continuous host immune reaction, including macrophage type 1 polarization, that resists osseointegration.
Da-Wang Zhao +11 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundThe efficacy of dupilumab as biological treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) depends on its ability to inhibit the pathophysiologic mechanisms involved in type 2 inflammation.ObjectiveTo assess in a ...
Corrado Pelaia +22 more
doaj +1 more source
Frontiers in Immunology, 2020 We previously demonstrated that IL4, IL13, CLCA1, and CCL26 mRNA were significantly upregulated in the lungs of pigs given a low dose of all trans-retinoic acid (ATRA) and infected with Ascaris suum.
Celine Chen +5 more
doaj +1 more source
Annals of Saudi Medicine, 2012 BACKGROUND AND OBJECTIVES: Acne vulgaris is a common skin disorder. The complete etiology of this disease remains to be identified; however, it seems that aberrant expression of cytokine genes might be a contributing factor.
Ahmad A. Al Robaee +3 more
doaj +1 more source