Results 171 to 180 of about 9,696,955 (392)

IL-6 Signaling in Immunopathology: From Basic Biology to Selective Therapeutic Intervention

open access: yesImmunoTargets and Therapy
Tim Schumertl, Juliane Lokau, Christoph Garbers Institute of Clinical Biochemistry, Hannover Medical School, Hannover, 30625, GermanyCorrespondence: Christoph Garbers, Institute of Clinical Biochemistry, Hannover Medical School, Carl-Neuberg-Strasse 1 ...
Schumertl T, Lokau J, Garbers C
doaj  

Prostaglandin‐Independent Stimulation of Interleukin‐6 Production by Fibrinogen Degradation Product D in Perfused Murine Liver [PDF]

open access: bronze, 1998
Miklós Csala   +8 more
openalex   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Interleukin-6: Molecular Pathophysiology

open access: yesJournal of Investigative Dermatology, 1990
The cytokine interleukin-6 (IL-6) has emerged as a major systemic alarm signal which appears to be produced by essentially every injured tissue. Recent evidence points to the skin, particularly the injured skin, as one of the major sites of IL-6 production.
openaire   +2 more sources

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro   +4 more
wiley   +1 more source

Supplementary Figure 6 from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases [PDF]

open access: gold, 2023
Ju-Yu Tseng   +9 more
openalex   +1 more source

Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]

open access: yes, 2011
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H.   +2 more
core  

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Interleukin-6 in systemic sclerosis and potential correlation with pulmonary involvement

open access: diamond, 2014
Mariam H.M. Yousif   +4 more
openalex   +1 more source

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