Results 51 to 60 of about 9,696,955 (392)

Taste and Smell Disorders in COVID-19 Patients: Role of Interleukin-6

ACS Chemical Neuroscience, 2020
The rapid recovery of smell and taste functions in COVID-19 patients could be attributed to a decrease in interleukin-6 levels rather than central nervous system ischemic injury or viral damage to neuronal cells.
A. Cazzolla, R. Lovero, L. Lo Muzio, N. F. Testa, A. Schirinzi, G. Palmieri, Pietro Pozzessere, V. Procacci, M. Di Comite, D. Ciavarella, M. Pepe, Caterina De Ruvo, V. Crincoli, Francesca Di Serio, L. Santacroce   +14 more
semanticscholar   +1 more source

Serum levels of interleukin-6 and interleukin-8 as diagnostic markers of acute pyelonephritis in children [PDF]

Korean Journal of Pediatrics, 2013
PurposeEarly diagnosis and treatment of acute pyelonephritis in children is of special importance in order to prevent serious complications. This study was conducted to determine the diagnostic value of serum interleukin (IL)-6 and IL-8 in children with ...
Abolfazl Mahyar, Parviz Ayazi, Mohammad Reza Maleki, Mohammad Mahdi Daneshi-Kohan, Hamid Reza Sarokhani, Hassan Jahani Hashemi, Mousa Talebi-Bakhshayesh   +6 more
doaj   +1 more source

Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]

, 1998
Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Cremer, Peter, Dehart, Isabelle, Fraunberger, Peter, Holler, Ernst, Nagel, Dorothea, Pfeiffer, Matthias, Seidel, Dietrich, Thein, Michael, Walli, Autar K.   +8 more
core   +1 more source

Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice [PDF]

, 2015
Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the
Berardinelli, Maria Grazia, Camilli, Carlotta, Catizone, Angela, De Benedetti, Fabrizio, Forcina, Laura, Musarò, Antonio, Nicoletti, Carmine, Pelosi, Laura, Rizzuto, Emanuele, Spelta, Elisa, Testa, Erika   +10 more
core   +2 more sources

Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes

Circulation Genomic and Precision Medicine, 2020
ownregulation of IL-6 (interleukin-6) signaling has been proposed as a strategy for lowering cardiovascular risk. Secondary analyses from CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) demonstrated that the therapeutic benefit of IL-1 β
Marios K. Georgakis, R. Malik, D. Gill, N. Franceschini, C. Sudlow, C. Sudlow, M. Dichgans, Sara Lindström, Lu Wang, Erin N. Smith, William Gordon, A. Vlieg, Mariza de Andrade, J. Brody, J. Pattee, Jeffery Haessler, B. Brumpton, D. Chasman, P. Suchon, Ming-Huei Chen, Constance Turman, M. Germain, K. Wiggins, James W. MacDonald, S. Braekkan, Sebastian M. Armasu, N. Pankratz, Rabecca D. Jackson, J. Nielsen, Franco Giulianini, M. Puurunen, Manal Ibrahim, S. Heckbert, S. Damrauer, P. Natarajan, D. Klarin, P. S. Vries, Maria Sabaterlleal, J. Huffman, T. Bammler, K. Frazer, Bryan M McCauley, K. Taylor, J. Pankow, Alex P. Reiner, M. Gabrielsen, J. Deleuze, Chris O'Donnell, Jihye Kim, B. McKnight, P. Kraft, John A. Hansen, F. Rosendaal, J. Heit, B. Psaty, Weihong Tang, C. Kooperberg, K. Hveem, P. Ridker, P. Morange, Andrew D. Johnson, C. Kabrhel, D. Trégouët, N. Smith, E. Benjamin, A. Dehghan, T. Ahluwalia, J. Meigs, R. Tracy, B. Alizadeh, Symen Ligthart, J. Bis, G. Eiriksdottir, M. Gross, A. Rainer, H. Snieder, James G. Wilson, J. Dupuis, B. Prins, Urmo Vaso, M. Stathopoulou, L. Franke, T. Lehtimäki, W. Koenig, Y. Jamshidi, S. Siest, A. Abbasi, A. Uitterlinden, M. Abdollahi, R. Schnabel, U. Schick, I. Nolte, A. Kraja, Y. Hsu, D. Tylee, A. Zwicker, R. Uher, G. Davey-Smith, A. Morrison, A. Hicks, C. Duijn, C. Ward‐Caviness, E. Boerwinkle, J. Rotter, Kenneth M. Rice, L. Lange, M. Perola, E. Geus, Andrew P. Morris, K. Makela, D. Stacey, J. Eriksson, T. Frayling, E. Slagboom   +113 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Association of Interleukin 6 Gene Variant and Interleukin 6 level in Children with Congenital Heart Diseases: Single Center Case – Control Study [PDF]

Pediatric Sciences Journal
Background: Etiology of most congenital heart diseases (CHDs) is multifactorial, they include genetic and environmental factors. Interleukin-6 (IL-6) gene variant rs1800795 was reported to be associated with CHD among Chinese children.
Hala Ashraf, Noha Bagdadi, Ahmed Said Behairy, Mahmoud Osman , Heba H. Zeid   +4 more
doaj   +1 more source

Criteria for the optimal use of interleukin-6 receptor blockers in patients with COVID-19

Терапевтический архив, 2021
Aim. To determine the criteria for the optimal use of IL-6 receptor blockers in patients with COVID-19 community-acquired pneumonia based on predictors of adverse outcomes. Materials and methods.
Tatyana S. Kruglova, Darya S. Fomina, Nataliya G. Poteshkina, Nadija F. Frolova, Irina P. Beloglazova, Zinaida Yu. Mutovina, Inna V. Samsonova, Elena A. Kovalevskaja, Alena I. Zagrebneva, Sofya A. Serdotetckova, Anton A. Chernov, Maryana A. Lysenko   +11 more
doaj   +1 more source

Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]

, 2013
Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien, Ducatelle, Richard, Erkens, Tim, Harris, Patricia, Hesta, Myriam, Janssens, Geert, Peelman, Luc   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source