Results 61 to 70 of about 1,103,478 (297)

The Significance of Serum and Fecal Levels of Interleukin-6 and Interleukin-8 in Hospitalized Children with Acute Rotavirus and Norovirus Gastroenteritis

Pediatrics and Neonatology, 2014
Rotavirus and norovirus are the most common known causes of viral gastroenteritis in children. This study examined the association between serum interleukin 6 (IL-6) and interleukin 8 (IL-8) levels and disease severity in the acute phase of rotavirus and
Shan-Ming Chen, Ching-Pin Lin, Jeng-Dau Tsai, Yu-Hua Chao, Ji-Nan Sheu   +4 more
doaj   +1 more source

Interleukins IL-6, IL-8, IL-10, IL-12 and periimplant disease. An update [PDF]

, 2011
Introduction: A study is made of the usefulness of cytokines (such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10) and interleukin-12 (IL-12)) as markers of periimplant disease (mucositis and periimplantitis).
Alegre Domingo, Teresa, Ata-Ali Mahmud, Francisco Javier, Candel Martí, Eugenia, Flichy Fernández, Antonio, Peñarrocha Diago, María   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]

, 2002
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR, Mirsky, R, Patterson, PH, Tofaris, GK   +3 more
core   +2 more sources

Expression of interleukin 1-alpha, interleukin 6 and CD 10 in predicting recurrence of ameloblastoma

Discover Oncology
Purpose Ameloblastoma (AM) is a clinically significant odontogenic tumour known for its local invasive and high post-treatment recurrence risk. Despite advancements in surgical techniques, predicting recurrence remains challenging.
Nurhazwani Mohd Danil, Bogahawatte Samarakoon Mudiyanselage Samadarani Siriwardena, Yet Ching Goh, Wanninayake Mudiyanselage Tilakaratne   +3 more
doaj   +1 more source

Comparison of spleen characterization and plasma levels of interleukin 6 and 10 in obese and healthy individuals [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: Spleen is one of the organs that has great importance in Iranian traditional medicine due to its relationship with obesity. Therefore, in this study, we aim to investigate spleen characterization and plasma levels of interleukin 6 ...
Mahdis Tanzifi, Mohammad Yousofpour, Amirsaeed Hosseini, Jamshid Yazdani Chrati, Tahereh Amirian   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interleukin (IL-6) Immunotherapy [PDF]

Cold Spring Harbor Perspectives in Biology, 2017
Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses.
Toshio, Tanaka, Masashi, Narazaki, Tadamitsu, Kishimoto   +2 more
openaire   +2 more sources

Fetal and early neonatal interleukin-6 response [PDF]

, 2015
In 1998, a systemic fetal cytokine response, defined as a plasma interleukin-6 (IL-6) value above 11 pg/mL, was reported to be a major independent risk factor for the subsequent development of neonatal morbid events even after adjustments for gestational
B. Resch, C. Chiesa, F. Natale, N. Hofer, OSBORN, John Frederick, PACIFICO, Lucia   +5 more
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source