Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
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Rapid transport of neural intermediate filament protein [PDF]
Peripherin is a neural intermediate filament protein that is expressed in peripheral and enteric neurons, as well as in PC12 cells. A determination of the motile properties of peripherin has been undertaken in PC12 cells during different stages of neurite outgrowth.
Brian T, Helfand +3 more
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Reconstitution of cytolinker-mediated crosstalk between actin and vimentin
Cell shape and motility are determined by the cytoskeleton, an interpenetrating network of actin filaments, microtubules, and intermediate filaments. The biophysical properties of each filament type individually have been studied extensively by cell-free
Irene Istúriz Petitjean +6 more
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Identification of an interchromosomal compartment by polymerization of nuclear-targeted vimentin [PDF]
A number of structural and functional subnuclear compartments have been described, including regions exclusive of chromosomes previously hypothesized to form a reactive nuclear space.
Bridger, JM +3 more
core
Inspired by the complex influence of the globular crosslinking proteins on the formation of biofilament bundles in living organisms, we study and analyze a theoretical model for the structure and thermodynamics of bundles of helical filaments assembled ...
Grason, Gregory M., Heussinger, Claus
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Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander +3 more
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Intermediate filament proteins in adult human arteries [PDF]
The cytoskeleton of cells in blood vessel walls contains desmin, vimentin, and cytokeratins. The distribution of these proteins in human vessels is not fully known. We have mapped the distribution of intermediate filament proteins in human arterial walls.Monoclonal antibodies targeted at the intermediate filament proteins desmin, vimentin, and ...
B, Johansson +3 more
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Defective axonal transport in motor neuron disease [PDF]
Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor neuron diseases. Mutations in genes that control microtubule regulation and dynamics have been shown to cause motor neuron degeneration in mice and in a ...
Baas +77 more
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Septins as membrane influencers: direct play or in association with other cytoskeleton partners
The cytoskeleton comprises three polymerizing structures that have been studied for a long time, actin microfilaments, microtubules and intermediate filaments, plus more recently investigated dynamic assemblies like septins or the endocytic-sorting ...
Béatrice Benoit +3 more
doaj +1 more source
Multiple sites in αB-crystallin modulate its interactions with desmin filaments assembled in vitro. [PDF]
The β3- and β8-strands and C-terminal residues 155-165 of αB-crystallin were identified by pin arrays as interaction sites for various client proteins including the intermediate filament protein desmin.
Scott A Houck +3 more
doaj +1 more source

