Results 61 to 70 of about 62,770 (250)

Desmin: molecular interactions and putative functions of the muscle intermediate filament protein

Brazilian Journal of Medical and Biological Research, 2004
Desmin is the intermediate filament (IF) protein occurring exclusively in muscle and endothelial cells. There are other IF proteins in muscle such as nestin, peripherin, and vimentin, besides the ubiquitous lamins, but they are not unique to muscle ...
M.L. Costa, R. Escaleira, A. Cataldo, F. Oliveira, C.S. Mermelstein   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Вплив гіпертиреозу на процеси навчання та стан гліальних проміжних філаментів головного мозку щурів

Regulatory Mechanisms in Biosystems, 2014
Досліджено вплив гіпертиреозу на показники окисного стресу, стан гліальних проміжних філаментів і пам’ять. У мозку щурів із гіпертиреозом визначено достовірне зростання вмісту продуктів перекисного окиснення ліпідів і погіршення процесу запам’ятовування.
S. V. Kyrychenko, V. S. Nedzvetsky
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Intermediate Filaments in Caenorhabditis elegans

, 2004
Abstract More than 70 different genes in humans and 12 different genes in Caenorhabditis elegans encode the superfamily of intermediate filament (IF) proteins. In C. elegans , similar to humans, these proteins are expressed in a cell- and tissue-specific manner, can assemble into heteropolymers and into 5–10 nm wide filaments that account for the ...
Fridkin, A., Karabinos, A., Gruenbaum, Y.   +2 more
openaire   +4 more sources

Neuroendocrine Carcinoma of the Skin (Merkel Cell Carcinoma): Immunocytochemical Study of a Case

The International Journal of Biological Markers, 1988
The immunocytochemical phenotype was evaluated in a case of Merkel cell carcinoma of the skin. Intermediate filaments, i.e. neurofilament, glial fibrillary acid protein, cytokeratins, keratin and panfilament as well as S-100 protein, calcitonin and ...
S. Senatore, L. Zizzi, D. D'Astore, G. Saccani Jotti, M. Gabrielli   +4 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Vimentin is a key regulator of cell mechanosensing through opposite actions on actomyosin and microtubule networks

Communications Biology
The cytoskeleton is a complex network of interconnected biopolymers consisting of actin filaments, microtubules, and intermediate filaments. These biopolymers work in concert to transmit cell-generated forces to the extracellular matrix required for cell
Farid Alisafaei, Kalpana Mandal, Renita Saldanha, Maxx Swoger, Haiqian Yang, Xuechen Shi, Ming Guo, Heidi Hehnly, Carlos A. Castañeda, Paul A. Janmey, Alison E. Patteson, Vivek B. Shenoy   +11 more
doaj   +1 more source