Results 41 to 50 of about 154,827 (291)
Star Formation and Gas Phase History of the Cosmic Web
We present a new method of tracking and characterizing the environment in which galaxies and their associated circumgalactic medium evolve. We use a structure finding algorithm we developed to self-consistently parse and follow the evolution of poor ...
Coughlin, Jared +4 more
core +1 more source
We investigate the thermal condensation caused by a massive object that passes through the interstellar medium with high velocity, and propose a mechanism for creating a filamentary gaseous object, or interstellar contrail.
Kanta Kitajima, Shu-ichiro Inutsuka
doaj +1 more source
Mechanical properties of branched actin filaments
Cells moving on a two dimensional substrate generate motion by polymerizing actin filament networks inside a flat membrane protrusion. New filaments are generated by branching off existing ones, giving rise to branched network structures.
Benetatos, Panayotis +3 more
core +1 more source
Computational and theoretical modeling of intermediate filament networks: Structure, mechanics and disease [PDF]
Intermediate filaments, in addition to microtubules and actin microfilaments, are one of the three major components of the cytoskeleton in eukaryotic cells.
Buehler, Markus J, Qin, Zhao
core +1 more source
This review systematically summarizes the central roles and molecular mechanisms of the cytoskeletal system—including actin filaments, microtubules (MT), intermediate filaments, and the Septin family—in the regulation of autophagy.
Xingyu Cao, Haolin Zhang, Juan Wang
doaj +1 more source
Hundred Thousand Degree Gas in the Virgo Cluster of Galaxies [PDF]
The physical relationship between low-excitation gas filaments at ~10^4 K, seen in optical line emission, and diffuse X-ray emitting coronal gas at ~10^7 K in the centers of many galaxy clusters is not understood.
Abramson +14 more
core +2 more sources
Cooperativity and Frustration in Protein-Mediated Parallel Actin Bundles
We examine the mechanism of bundling of cytoskeletal actin filaments by two representative bundling proteins, fascin and espin. Small-angle X-ray studies show that increased binding from linkers drives a systematic \textit{overtwist} of actin filaments ...
B. Alberts +6 more
core +1 more source
Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]
Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S. +4 more
core +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

