Results 31 to 40 of about 62,770 (250)
Epithelial Intermediate Filaments: Guardians against Microbial Infection?
Cells, 2016 Intermediate filaments are abundant cytoskeletal components of epithelial tissues. They have been implicated in overall stress protection. A hitherto poorly investigated area of research is the function of intermediate filaments as a barrier to microbial
Florian Geisler, Rudolf E. Leube
doaj +1 more source
Intermediate Filaments: Vimentin Moves in [PDF]
Current Biology, 2002 Vimentin intermediate filaments move bi-directionally along microtubules in the cell. Recent work has identified the microtubule motor cytoplasmic dynein as the missing inward-directed motor that drives this movement.
Clarke, Emma J., Allan, Viki
openaire +3 more sources
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2016 This article clarifies the questions on study of hypoxic influence on distribution of filament and soluble forms of GFAP in various structures of the brain (neocortex, cerebellum, hippocampus, striatum, middle brain, pons) and blood of the rats ...
T. I. Duka, V. I. Chоrna
doaj +1 more source
The Astrophysical Journal, 2023 We investigate the thermal condensation caused by a massive object that passes through the interstellar medium with high velocity, and propose a mechanism for creating a filamentary gaseous object, or interstellar contrail.
Kanta Kitajima, Shu-ichiro Inutsuka
doaj +1 more source
Frontiers in ImmunologyThis review systematically summarizes the central roles and molecular mechanisms of the cytoskeletal system—including actin filaments, microtubules (MT), intermediate filaments, and the Septin family—in the regulation of autophagy.
Xingyu Cao, Haolin Zhang, Juan Wang
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers
Cell Reports, 2015 The actin cytoskeleton and cytoplasmic intermediate filaments contribute to cell migration and morphogenesis, but the interplay between these two central cytoskeletal elements has remained elusive.
Yaming Jiu +8 more
doaj +1 more source
Reaction of Sera from Infertile Female Patients with Fractionated Phylogenetically Conserved Ovarian Antigens Measured by Elisa: A Pilot Study [PDF]
Journal of Biomedical & Clinical Research, 2017 The reaction of anti-sperm antibody-positive sera from infertile women with fractionated mouse ovarian antigens was measured by enzyme-linked immunosorbent assay (ELISA). Antigens were obtained by extraction for nuclear matrix and intermediate filaments (
Stefka Delimitreva +5 more
doaj +3 more sources